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Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018
Chelerythrine (CHE) is a type of benzophenanthridine alkaloid found in many herbs and is also the main alkaloid constituent of Toddalia asiatica (L.) Lam. It... 
metastasis | Chelerythrine | hepatocellular carcinoma
Journal Article
Pesticide Biochemistry and Physiology, ISSN 0048-3575, 01/2020
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 05/2015, Volume 570, pp. 58 - 65
The isoquinoline alkaloid chelerythrine is described as an inhibitor of SERCA. The ATPase inhibition presented two non-competitive components, K i1 = 1, 2 μM... 
Calcium | ATPase | Chelerythrine | Cytotoxicity | SERCA | PBMC
Journal Article
RSC Advances, ISSN 2046-2069, 2016, Volume 6, Issue 47, pp. 41173 - 41180
Three pairs of new enantiomeric natural alkaloids (+/-)-macleayins C-E (1-3), together with five pairs of known racemic alkaloids (4-8), were isolated from the... 
SANGUINARINE | CELLS | CHELERYTHRINE | TRITERPENOIDS | CHEMISTRY, MULTIDISCIPLINARY | CORYDALIS
Journal Article
Journal of Photochemistry & Photobiology, B: Biology, ISSN 1011-1344, 08/2016, Volume 161, pp. 335 - 344
The interaction of the putative anticancer alkaloid chelerythrine with tRNAphe was characterized by spectroscopy, calorimetry and molecular docking studies.... 
Thermodynamics | Docking studies | tRNAphe | Interaction | Benzophenanthridine alkaloid | Chelerythrine | tRNA
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2008, Volume 51, Issue 21, pp. 6699 - 6710
Despite their structural similarities, the natural products chelerythrine (5) and sanguinarine (6) target different binding sites on the pro-survival Bcl-X-L... 
CHELERYTHRINE | CHEMISTRY, MEDICINAL | ARYL COUPLING REACTION | SMALL-MOLECULE INHIBITORS | BIARYL | PROTEINS | CYCLIZATION | DISCOVERY | ALKALOIDS
Journal Article
TOXINS, ISSN 2072-6651, 07/2019, Volume 11, Issue 7, p. 406
Chelidonium majus (Papaveraceae) extracts exhibit antimicrobial activity due to the complex alkaloid composition. The aim of the research was to evaluate the... 
isoquinoline alkaloids | Chelidonium majus | CHELERYTHRINE | HIGHER-PLANTS | SANGUINARINE | AGENTS | TOXICOLOGY | antimicrobial activity | QUATERNARY | CYTOTOXICITY | BINDING
Journal Article
Journal of Photochemistry and Photobiology. B, Biology, ISSN 1011-1344, 09/2017, Volume 174, p. 173
Single stranded RNAs are biologically potent as they participate in various key cellular processes. The binding efficacy of two potent anticancer alkaloids,... 
Binding | Enthalpy | Chelerythrine | Entropy | Effects | Ribonucleic acid--RNA | Sanguinarine | Anticancer properties | Alkaloids | Staking | Affinity | Cancer | Conformation
Journal Article
Toxicology Letters, ISSN 0378-4274, 09/2019, Volume 311, pp. 91 - 97
•Major Chelidonium majus alkaloids are cytotoxic in rat hepatocytes in primary culture.•CAL differ widely in their cytotoxic potency, the cationic congeners... 
Alkaloids | Chelidonium majus | Rat hepatocytes | Sanguinarine | Hepatotoxicity | Papaveraceae | Glutathione | CHELERYTHRINE | MAJUS L | QUATERNARY | INHIBITION | GLUTATHIONE DISULFIDE | TOXICOLOGY | Phosphates | Animal experimentation | Liver diseases | Liver | Rankings | Glucose | Dextrose
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 04/2019, Volume 848, pp. 131 - 139
Exposure of G protein–coupled receptors (GPCRs) to agonists can desensitize receptor signaling and lead to drug tolerance, whereas inverse agonists can... 
phospholipase C | Aminotetralin | 5-HT2C receptor | Sensitization | Desensitization | β-arrestin | CHELERYTHRINE | PHOSPHORYLATION | beta-arrestin | PROTEIN-KINASE | MECHANISMS | DISCOVERY | RAPID DESENSITIZATION | LORCASERIN | RECOMBINANT | PHARMACOLOGY | INVERSE AGONIST | PHARMACOLOGY & PHARMACY
Journal Article
Pesticide Biochemistry and Physiology, ISSN 0048-3575, 05/2018, Volume 147, pp. 3 - 10
[Display omitted] •Three groups of 32 sanguinarine analogues were synthesized via facile methods and characterized.•Their fungicidal activities were evaluated... 
Rhizoctonia solani | Alkaloid | Sanguinarine | Fungicide | CHELERYTHRINE | PHYSIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIFUNGAL ACTIVITY | QUATERNARY | ENTOMOLOGY | ALKALOIDS
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1941 - 12
Thirty new title compounds along with five known analogues were prepared from commercially available 2-arylhydrazin-1-ium chlorides and alpha-ketoglutaric... 
VITRO ACARICIDAL ACTIVITY | CHELERYTHRINE | MULTIDISCIPLINARY SCIENCES | BIOLOGICAL EVALUATION | SANGUINARINE | CYTOTOXIC ACTIVITY | SALTS | DERIVATIVES | Fungi | Growth rate | Antifungal agents | Azoxystrobin | Ketoglutaric acid | Carbendazim | Biological activity | Thiabendazole
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 10/2016, Volume 24, Issue 19, pp. 4600 - 4610
Journal Article
RSC Advances, ISSN 2046-2069, 2016, Volume 6, Issue 56, pp. 50500 - 50505
A novel photoredox-mediated direct intermolecular C–H functionalization ofN-methyl 5,6-dihydrobenzophenanthridine is developed utilizing the visible... 
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 17988 - 9
Macleaya cordata produces a variety of benzylisoquinoline alkaloids (BIAs), such as sanguinarine, protopine, and berberine, which are potential anticancer... 
SYNTHASE | SANGUINARINE | LEVEL | CULTURES | MULTIDISCIPLINARY SCIENCES | Alkaloids | Berberine | Enzymes | Antitumor agents | Chelerythrine | Mass spectroscopy | Metabolic engineering | Liquid chromatography | Biosynthesis | Sanguinarine
Journal Article
Environmental Pollution, ISSN 0269-7491, 10/2019, Volume 253, pp. 497 - 506
Sanguinarine has strong inhibitory effects against the cyanobacterium Microcystis aeruginosa. However, previous studies were mainly limited to laboratory... 
Cyanobacterial bloom | Algicide | Sanguinarine | Microbial community structure | Pyrosequencing | CHELERYTHRINE | MICROCYSTIS-AERUGINOSA | FATTY-ACIDS | ENVIRONMENTAL SCIENCES | NUTRIENT RELEASE | PRECIPITATION | LAKE TAIHU | GROWTH | OPTIMIZATION | PHYTOPLANKTON | WATER | Microbiology | Bioremediation | Index Medicus
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 01/2013, Volume 64, pp. 37 - 44
PKM zeta is an autonomously active, atypical protein kinase C (aPKC) isoform that is both necessary and sufficient for maintaining long-term potentiation (LTP)... 
ZIP | PKN zeta | PROTEIN-KINASE-C | ACTIVATION | MECHANISM | SPECIFICITY | Staurosporine | PHOSPHORYLATION | Chelerythrine | aPKC | NEUROSCIENCES | MAINTENANCE | MEMORY | ENHANCEMENT | PHARMACOLOGY & PHARMACY | LONG-TERM POTENTIATION
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 01/2020, Volume 135, p. 110933
Chelerythrine (CHE), a benzophenanthridine alkaloid, is usually used as a nutritional and functional additive in variety of health foods. However, it should be... 
Bovine serum albumin | Toxicity | Binding mechanism | Spectroscopic approaches | Chelerythrine | Thermodynamics | Protein Conformation, alpha-Helical - drug effects | Animals | Cattle | Protein Binding | Spectrometry, Fluorescence | Serum Albumin, Bovine - metabolism | Binding Sites | Circular Dichroism | Benzophenanthridines - metabolism
Journal Article
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