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Journal of Investigative Dermatology, ISSN 0022-202X, 12/2018, Volume 138, Issue 12, pp. 2501 - 2504.e1
Chimeric antigen receptor (CAR) and chimeric autoantibody receptor T-cell therapy hold great promise in the treatment of cancer and autoimmune disease,... 
CHIMERIC ANTIGEN RECEPTOR | DERMATOLOGY
Journal Article
BLOOD, ISSN 0006-4971, 05/2019, Volume 133, Issue 21, pp. 2246 - 2247
In this issue of Blood, Sanchez-Martinez and colleagues present a novel approach to the treatment of T-acute lymphoblastic leukemia (T-ALL) using chimeric... 
ADULTS | HEMATOLOGY | CHIMERIC ANTIGEN RECEPTOR
Journal Article
Biotechnology Advances, ISSN 0734-9750, 2019
T cells engineered to express a chimeric antigen receptor (CAR) have re-shaped the way hematological malignancies are treated. Despite the overwhelming early... 
Chimeric antigen receptor | Biotechnology | Immunotherapy
Journal Article
Cancer Discovery, ISSN 2159-8274, 12/2017, Volume 7, Issue 12, pp. 1404 - 1419
Lymphodepletion chemotherapy followed by infusion of CD19-targeted chimeric antigen receptor-modified T (CAR-T) cells can be complicated by neurologic adverse... 
SUSTAINED REMISSIONS | MANAGEMENT | B-CELL | ONCOLOGY | THROMBOSIS | MALIGNANCIES | SERUM | CHIMERIC ANTIGEN RECEPTOR | LEUKEMIA | PERICYTES | TOCILIZUMAB | chimeric antigen receptor | neurotoxicity | cytokine release syndrome | CAR | CD19
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 07/2019, Volume 25, Issue 18, pp. 5595 - 5607
CD19 chimeric antigen receptor (CAR)-T therapy has shown impactful results in treatment of B-cell malignancies. However, immune recognition of the murine scFv... 
CHIMERIC ANTIGEN RECEPTOR | MODIFIED T-CELLS | ONCOLOGY | CD19
Journal Article
European urology, ISSN 0302-2838, 08/2019
Progress achieved in the treatment of prostate cancer (PCa) with surgical, radiation, and hormonal therapies has drastically reduced mortality from this... 
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 02/2017, Volume 23, Issue 2, pp. 242 - 249
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative therapy for hematological malignancies. However, graft-versus-host... 
MEDICINE, RESEARCH & EXPERIMENTAL | PERSISTENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GVHD | INFUSION | CHIMERIC ANTIGEN RECEPTOR | TRANSPLANTATION | CELL BIOLOGY | CD19-TARGETED T-CELLS | REMISSIONS | HEMATOLOGICAL MALIGNANCIES | EXHAUSTION | LYMPHOCYTES
Journal Article
The Oncologist, ISSN 1083-7159, 08/2018, Volume 23, Issue 8, pp. 943 - 947
On August 30, 2017, the U.S. Food and Drug Administration approved Actemra (tocilizumab, Genentech, Inc., South San Francisco, CA) for the treatment of severe... 
Cytokine release syndrome | Chimeric antigen receptor | Interleukin‐6 | Tocilizumab | T cell | Immunotherapy | Interleukin-6 | MANAGEMENT | ONCOLOGY | REMISSIONS | LEUKEMIA | FDA | Regulatory Issues
Journal Article
Cellular immunology, ISSN 0008-8749, 08/2019, p. 103964
A cure for multiple myeloma (MM), a malignancy of plasma cells, remains elusive. Nearly all myeloma patients will eventually relapse and develop resistance to... 
Journal Article
Clinical Lymphoma, Myeloma and Leukemia, ISSN 2152-2650, 09/2018, Volume 18, pp. S134 - S136
Journal Article
Revue d'Oncologie Hematologie Pediatrique, ISSN 2213-4670, 12/2016, Volume 4, Issue 4, pp. 202 - 209
The treatment of relapsed or refractory leukemia remains a major challenge in pediatric and adult patients. A better understanding of the immune system in... 
Chimeric antigen receptor | CAR
Journal Article
Nature Reviews Clinical Oncology, ISSN 1759-4774, 05/2016, Volume 13, Issue 5, pp. 273 - 290
In the past decade, advances in the use of monoclonal antibodies (mAbs) and adoptive cellular therapy to treat cancer by modulating the immune response have... 
METASTATIC MELANOMA | CTLA-4 BLOCKADE | ONCOLOGY | CYTOKINE RELEASE SYNDROME | LONG-TERM SURVIVAL | ACUTE LYMPHOBLASTIC-LEUKEMIA | CHIMERIC ANTIGEN RECEPTOR | MODIFIED T-CELLS | ACUTE MYELOID-LEUKEMIA | CHRONIC VIRAL-INFECTION | ANTITUMOR-ACTIVITY | Usage | Cell receptors | Care and treatment | Immunotherapy | Innovations | Monoclonal antibodies | Properties | Methods | Cancer
Journal Article
Science Translational Medicine, ISSN 1946-6234, 03/2015, Volume 7, Issue 280, pp. 280ps7 - 280ps7
Adoptive T cell transfer for cancer, chronic infection, and autoimmunity is an emerging field that shows promise in recent trials. Using the principles of... 
MEDICINE, RESEARCH & EXPERIMENTAL | HIV | SAFETY | IMMUNE-RESPONSES | CHIMERIC-ANTIGEN-RECEPTOR | IMMUNOTHERAPY TARGETS | LENTIVIRAL GENE-TRANSFER | MODIFIED T-CELLS | OVARIAN-CANCER | ANTITUMOR-ACTIVITY | TRANSPLANTATION | CELL BIOLOGY | T-Lymphocytes - immunology | Genetic Engineering | Adoptive Transfer - adverse effects | Humans
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 01/2016, Volume 16, Issue 1, pp. 7 - 19
Journal Article