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PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, p. e113300
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 10/2015, Volume 33, Issue 30, pp. 3409 - 3415
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Leukemia Research, ISSN 0145-2126, 09/2018, Volume 72, pp. 71 - 73
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Journal Article
Journal Article
Leukemia, ISSN 0887-6924, 04/2015, Volume 29, Issue 4, pp. 807 - 818
AZD1775 targets the cell cycle checkpoint kinase Wee1 and potentiates genotoxic agent cytotoxicity through p53-dependent or -independent mechanisms. Here, we... 
CYCLIN-DEPENDENT KINASES | GENOMIC INSTABILITY | HISTONE DEACETYLASE INHIBITOR | DNA-DAMAGING AGENTS | ONCOLOGY | MITOTIC CATASTROPHE | THERAPEUTIC TARGET | TUMOR-CELLS | HOMOLOGOUS RECOMBINATION | HEMATOLOGY | PRECLINICAL EVALUATION | CANCER-THERAPY | Protein Kinases - metabolism | CDC2 Protein Kinase | Phosphorylation | Protein Kinases - genetics | Cyclin-Dependent Kinases - metabolism | Apoptosis - drug effects | Protein-Tyrosine Kinases - metabolism | Humans | Tumor Suppressor Protein p53 - genetics | Cell Cycle Proteins - antagonists & inhibitors | fms-Like Tyrosine Kinase 3 - genetics | Protein-Tyrosine Kinases - genetics | Cell Cycle Proteins - genetics | Leukemia, Myeloid, Acute - drug therapy | Cyclin-Dependent Kinases - antagonists & inhibitors | DNA Fragmentation - drug effects | Cyclin-Dependent Kinases - genetics | Drug Therapy, Combination | Nuclear Proteins - genetics | Hydroxamic Acids - pharmacology | Signal Transduction | Leukemia, Myeloid, Acute - pathology | Cell Cycle Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Gene Expression Regulation, Leukemic | fms-Like Tyrosine Kinase 3 - metabolism | Drug Synergism | Leukemia, Myeloid, Acute - mortality | Xenograft Model Antitumor Assays | Animals | Cell Cycle Checkpoints - drug effects | Nuclear Proteins - antagonists & inhibitors | Survival Analysis | Myeloid Cells - metabolism | Checkpoint Kinase 1 | Histone Deacetylase Inhibitors - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Myeloid Cells - pathology | Primary Cell Culture | Leukemia, Myeloid, Acute - genetics | Protein-Tyrosine Kinases - antagonists & inhibitors | checkpoint | AML | HDAC inhibitor | Cdk1 | Chk1 | Wee1 inhibitor | cdc2
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 09/2008, Volume 7, Issue 9, pp. 2955 - 2966
Journal Article