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PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0180190
Journal Article
Science, ISSN 0036-8075, 10/2007, Volume 318, Issue 5848, pp. 208 - 209
Inkjet printing technology offers a way to create three-dimensional biological structures for studying cell interactions and artificial organs. 
Printing | Stem cells | Cell lines | Nozzles | Cell communication | Materials science | Perspectives | CHO cells | Inkjet printers | Animal cells | Computer printers | CONSTRUCTS | MULTIDISCIPLINARY SCIENCES | TISSUE | LIVING CELLS
Journal Article
Science, ISSN 0036-8075, 4/2011, Volume 332, Issue 6029, pp. 600 - 603
Journal Article
Journal Article
Immunology, ISSN 0019-2805, 10/2017, Volume 152, Issue 2, pp. 265 - 275
Summary Induction of tolerance is a key mechanism to maintain or to restore immunological homeostasis. Here we show that Foxp3+ regulatory T (Treg) cells use... 
regulatory T cells | Dickkopf‐1 | autoimmune colitis | Dickkopf-1 | THERAPY | RECEPTOR | WNT ANTAGONIST DICKKOPF-1 | IMMUNOLOGY | EXPRESSION | DKK1 | MASTER REGULATOR | Autoimmunity | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Cell Proliferation | Cricetulus | Colitis - genetics | Colitis - pathology | Colon - immunology | Adoptive Transfer | DNA-Binding Proteins - deficiency | T-Lymphocytes, Regulatory - immunology | Autoimmune Diseases - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Transfection | Time Factors | Forkhead Transcription Factors - metabolism | Cell Membrane - metabolism | Intercellular Signaling Peptides and Proteins - deficiency | Colitis - immunology | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | CHO Cells | Disease Models, Animal | Genetic Predisposition to Disease | Signal Transduction | Colon - pathology | Lymphocyte Activation | Mice, Inbred C57BL | Autoimmune Diseases - immunology | Intercellular Signaling Peptides and Proteins - genetics | Self Tolerance | DNA-Binding Proteins - genetics | Forkhead Transcription Factors - genetics | Colon - metabolism | Mice, Knockout | Phenotype | Animals | Colitis - metabolism | Cell Membrane - immunology | T-Lymphocytes, Regulatory - transplantation | Intercellular Signaling Peptides and Proteins - immunology | Mitogen-Activated Protein Kinases - metabolism | Analysis | Monoclonal antibodies | Protein biosynthesis | Colitis | T cells | Mitogens | Protein kinases | Cell proliferation | Wnt protein | Homeostasis | Effector cells | Lymphocytes T | In vitro testing | Kinases | Thymus | T-cell receptor | Immunology | Lymphocytes | Rodents | Foxp3 protein | Immunoregulation | MAP kinase | T cell receptors | Immunological tolerance | CD4 antigen | Inflammatory bowel disease | Protein synthesis | Protein kinase | Dkk1 protein | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40443
TH17 cells enter tissues to facilitate pathogenic autoimmune responses, including multiple sclerosis (MS). However, the adhesion molecules involved in the... 
MIGRATION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | IN-VITRO | ADHESION MOLECULE | MULTIPLE-SCLEROSIS | BIOLOGY | RECEPTOR | MEMORY CELLS | EXPRESSION | T-CELLS | LYMPHOCYTES | Cell Polarity | Cell Proliferation | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Choroid Plexus - metabolism | Th17 Cells - secretion | Choroid Plexus - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Extracellular Matrix - metabolism | Laminin - physiology | Interleukins - metabolism | Th17 Cells - metabolism | Female | CHO Cells | Cricetinae | Interleukin-1beta - physiology | Th17 Cells - physiology | Encephalomyelitis, Autoimmune, Experimental - pathology | Choroid Plexus - pathology | Interleukin-17 - secretion | Mice, Knockout | Interleukin-17 - metabolism | Animals | CD146 Antigen - metabolism | Protein Binding | Ligands | Mice | Cell Movement | Interleukins - secretion | Autoimmunity | Monoclonal antibodies | Multiple sclerosis | Laminin | B cells | T cells | Membranes | Laboratories | Salespeople | Central nervous system | Helper cells | Lymphocytes T | Metastasis | Gene deletion | Cell adhesion & migration | Cell adhesion molecules | Proteins | Clonal deletion | Lymphocytes | Animal tissues | Cell adhesion | Deletion | Inhibition | Binding | Antigens | Business travel | Immunological memory | Memory cells | Cytokines | Cloning | Melanoma | Inflammation | Basement membranes | Adhesion | Interleukin 17 | Infiltration | Cell migration | Cancer | Pharmaceuticals
Journal Article
Journal Article
mAbs, ISSN 1942-0862, 01/2015, Volume 7, Issue 3, pp. 584 - 604
To harness the potent tumor-killing capacity of T cells for the treatment of CD19(+) malignancies, we constructed AFM11, a humanized tetravalent bispecific... 
Non-Hodgkin lymphoma | ALL | CD3 | T cells | Bispecific antibodies | NHL, non-Hodgkin lymphoma | CHO, Chinese hamster ovary | ACTIVATION | MWCO, molecular weight cut-off | FC-RECEPTORS | MONOCLONAL-ANTIBODY | PROLIFERATION | BBB, blood-brain barrier | WBA, whole body autoradiography | KD, dissociation constant | ECL, electrochemiluminescence | FACS, fluorescence-activated cell sorting | LYMPHOMA | CCS, cell culture supernatant | SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis | ANALYSIS TOOL | i.v., intravenous | ORR, overall response rate | PI, propidium iodide | TNF, tumor necrosis factor | VH, variable heavy | Vss, volume of distribution at steady state | PBS, phosphate buffered saline | FcRn, neonatal Fc receptor | Fab, fragment antigen-binding | ctrl., control | t(1/2), terminal elimination half-life | BITE ANTIBODY BLINATUMOMAB | IgG, immunoglobulin G | B-ALL, B-precursor acute lymphoblastic leukemia | NK, natural killer | E:T, effector:target | CLL, chronic lymphocytic leukemia | IL, interleukin | MALIGNANCIES | s.c., subcutaneous | His, histidine | FR, framework region | EC50, half maximal effective concentration | FCS, fetal calf serum | MEDICINE, RESEARCH & EXPERIMENTAL | CONSTRUCT | kd, dissociation rate constant | w/o, without | Fc, fragment crystallizable | LMF, low molecular weight forms | VL, variable light | HMF, high molecular weight forms | FcgR, Fc gamma receptor | F, fluorescence | SABC, standardized antibody binding capacity | SE-HPLC, size exclusion high-pressure liquid chromatography | CD, cluster of differentiation | CL, clearance | ACUTE LYMPHOBLASTIC-LEUKEMIA | SD, standard deviation | SEC, size exclusion chromatography | PBMC, peripheral blood mononuclear cell | scFv, single-chain variable fragment | IFN, interferon | MSD, MesoScale Discovery | BiTE, bispecific T cell engager | PHA, phytohemagglutinin | Fv, variable fragment | CAR, chimeric antigen receptor | HSA, human serum albumin | AUCtot, total area under the curve | PES, polyethersulfone | CNS, central nervous system | TandAb, tandem diabody | CDR, complementarity determining region | ka, association rate constant | DMSO, dimethyl sulfoxide | SPR, surface plasmon resonance | NOD/scid, nonobese diabetic/severe combined immunodeficiency | Cmax, maximal concentration | Cricetulus | Humans | Male | Neoplasms, Experimental - pathology | Antibodies, Neoplasm - pharmacology | Neoplasms, Experimental - immunology | HEK293 Cells | Antigens, CD19 - immunology | CHO Cells | Antibodies, Neoplasm - immunology | Cricetinae | Single-Chain Antibodies - pharmacology | Antibodies, Bispecific - pharmacology | Jurkat Cells | Mice, SCID | Antibodies, Bispecific - immunology | Xenograft Model Antitumor Assays | Animals | CD3 Complex - immunology | Antibodies, Bispecific - chemistry | Mice, Inbred NOD | Antibodies, Neoplasm - chemistry | Mice | Neoplasms, Experimental - drug therapy | Single-Chain Antibodies - chemistry | Single-Chain Antibodies - immunology
Journal Article
Nature Immunology, ISSN 1529-2908, 04/2019, Volume 20, Issue 4, pp. 458 - 470
Journal Article
Journal Article