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chrna5 (75) 75
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nicotinic receptors (8) 8
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15q25 (6) 6
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Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2015, Volume 16, Issue 15, pp. 6685 - 6690
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 11/2017, Volume 18, Issue 11, pp. 3073 - 3079
Background: The 15q24-25 loci contain genes (CHRNA5 and CHRNA3) encoding nicotinic acetylcholine receptor subunits. We here determined for the first time the... 
North Indian | Rs16969968 | CHRNA5 | SNP | Lung cancer | Smoking | rs16969968 | smoking | north Indian
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 2, pp. 2435 - 2444
CHRNA5/CHRNA3/CHRNB4 gene cluster is located on chromosome 15q25.1 and was reported to be associated with risk of lung cancer. So far, the effect of three... 
CHRNA5/CHRNA3/CHRNB4 | Single nucleotide polymorphism | Interaction | Non-small cell lung cancer | Smoking | non-small cell lung cancer | SURVIVAL | FUNCTIONAL POLYMORPHISM | NICOTINE | single nucleotide polymorphism | SUSCEPTIBILITY | LOCI | CELL BIOLOGY | REPLICATION | PATHWAY GENES | smoking | interaction | 15Q25 | BEHAVIORS | GENOME-WIDE ASSOCIATION
Journal Article
by Yang, XJ and Guo, XD and Huang, Z and Da, YF and Xing, WH and Li, F and Li, ML and Sun, K and Jia, HY and Zhu, Y
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, ISSN 1749-799X, 07/2019, Volume 14, Issue 1, pp. 243 - 243
BackgroundLumbar disc herniation, a type of chronic low back pain syndrome, is caused by the lumbar intervertebral disk degeneration. Genetic variation in the... 
CHRNA3 | CHRNA5 | LOW-BACK-PAIN | VARIANTS | Lumbar disc herniation | Susceptibility | Single-nucleotide polymorphism | SMOKING | POLYMORPHISM | DEGENERATION | LUNG-CANCER | DISEASE | INTERVERTEBRAL DISC | ORTHOPEDICS | ASSOCIATION | Medical research | Genes | Genetic research | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Backache | Risk factors | Index Medicus | CHRNA5/CHRNA3
Journal Article
The Journal of neuroscience : the official journal of the Society for Neuroscience, ISSN 0270-6474, 01/2019, Volume 39, Issue 5, pp. 783 - 785
Brynildsen focuses on the role of the rostral interpeduncular nucleus in aversion to nicotine clarifying the reports by Morton et al. genetic and environmental... 
VARIANTS | CHRNA5 | RISK | SINGLE NUCLEOTIDE POLYMORPHISM | SMOKING | RECEPTORS | ASSOCIATION | NEUROSCIENCES | Drug abuse | Drug addiction | Aversion | Information processing | Electrophysiology | Reinforcement | Optics | Acetylcholine receptors (nicotinic) | Genetics | Environmental factors | Nicotine | Journal Club
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 04/2012, Volume 62, Issue 5-6, pp. 1935 - 1943
Desensitization is a complex property of nicotinic acetylcholine receptors (nAChR). Several subtypes of nAChR have high sensitivity to nicotine and mediate... 
MOUSE-BRAIN | NERVOUS-SYSTEM | Desensitization | Chrna5 subunit | Dopamine | Chrna6 subunit | SUBTYPES | LOW-SENSITIVITY | NEUROSCIENCES | DEPENDENCE | PHARMACOLOGY | GABA | PHARMACOLOGY & PHARMACY | BINDING-SITES | EXPRESSION | RB-86(+) EFFLUX | Nicotine | ALPHA-4-BETA-2
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 08/2018, Volume 138, pp. 371 - 380
Preclinical studies suggest the involvement of various subtypes of nicotinic acetylcholine receptors in the pathophysiology of Parkinson's disease, a... 
Parkinson's disease | Chrna5 subunit | Dopamine | TRANSPORTER | PHOSPHORYLATION | Substantia nigra | DOPA-INDUCED DYSKINESIAS | RELEASE | Nicotinic receptors | Levodopa-induced dyskinesia | SUBSTANTIA-NIGRA | NEUROTOXICITY | NEUROSCIENCES | PHARMACOLOGY & PHARMACY | 6-HYDROXYDOPAMINE | STRIATUM | MODULATION | PARKINSONS-DISEASE
Journal Article
Schizophrenia Research, ISSN 0920-9964, 04/2019, Volume 206, pp. 407 - 412
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 03/2016, Volume 30, Issue 3, pp. 1109 - 1119
Prototoxins are a diverse family of membrane-tethered molecules expressed in the nervous system that modulate nicotinic cholinergic signaling, but their... 
LYNX1 | LYNX2 | CHRNA5 | PSCA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | Ly6/uPAR | DEPENDENCE | CELL BIOLOGY | HAIR-CELLS | ALTERNATE STOICHIOMETRIES | FUNCTIONAL EXPRESSION | PHARMACOLOGY | IN-VIVO | BIOLOGY | NEURONS | CHOLINERGIC-RECEPTORS | SUBUNIT
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2016, Volume 30, Issue 3, pp. 1109 - 1119
Prototoxins are a diverse family of membrane-tethered molecules expressed in the nervous system that modulate nicotinic cholinergic signaling, but their... 
LYNX1 | LYNX2 | CHRNA5 | PSCA | Ly6/uPAR | Receptors, Urokinase Plasminogen Activator - metabolism | Receptors, Nicotinic - metabolism | Animals | Acetylcholine - pharmacology | Oocytes - metabolism | Xenopus laevis - metabolism | Humans | Oocytes - drug effects | Protein Subunits - metabolism | Nicotine - pharmacology | Index Medicus | Research Communication | Ly6 | uPAR
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 11/2012, Volume 63, Issue 6, pp. 1002 - 1011
The human CHRNA5 D398N polymorphism (rs16969968) causes an aspartic acid to asparagine change in the nicotinic acetylcholine receptor (nAChR) alpha 5 subunit... 
MOUSE-BRAIN | CHRNA5 | Intracellular calcium | MESSENGER-RNA EXPRESSION | EUROPEAN-AMERICANS | LATERAL HABENULA | FUNCTIONAL-CHARACTERIZATION | NEUROSCIENCES | MICE LACKING | DOPAMINERGIC TERMINALS | Alpha5 subunit | rs16969968 | LUNG-CANCER | Nicotinic acetylcholine receptors | CHANNEL CONDUCTANCE | PHARMACOLOGY & PHARMACY | Polymorphism | SUBUNIT
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 2013, Volume 4, pp. 251 - 251
Journal Article
BIOLOGICAL PSYCHIATRY, ISSN 0006-3223, 01/2012, Volume 71, Issue 2, pp. 120 - 128
Background: Nicotinic signaling in prefrontal layer VI pyramidal neurons is important to the function of mature attention systems. The normal incorporation of... 
CHOLINERGIC-RECEPTOR | CHRNA5 | PSYCHIATRY | prefrontal cortex | DEFICIT-HYPERACTIVITY-DISORDER | BETA-2 SUBUNITS | AUTISM SPECTRUM DISORDERS | CORTICAL DEVELOPMENT | NEUROSCIENCES | neuronal morphology | REACTION-TIME-TASK | CEREBRAL-CORTEX | ACETYLCHOLINE-RECEPTORS | IN-VIVO | layer VI | RAT-BRAIN | alpha 5 subunit | nicotinic acetylcholine receptor
Journal Article
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