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Nature Reviews Genetics, ISSN 1471-0056, 01/2012, Volume 13, Issue 1, pp. 59 - 69
Cis-regulatory sequences, such as enhancers and promoters, control development and physiology by regulating gene expression. Mutations that affect the function... 
MORPHOLOGICAL EVOLUTION | TRANSCRIPTION FACTOR-BINDING | DROSOPHILA-MELANOGASTER | INSECTICIDE RESISTANCE | DNA | GENETICS & HEREDITY | GENE-EXPRESSION | TRANSPOSABLE ELEMENTS | EVO-DEVO | ENHANCER | CARRYING HUMAN-CHROMOSOME-21 | Genetic aspects | Research | Gene mutations | Gene expression | Divergent evolution | Biological diversity
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2010, Volume 30, Issue 45, pp. 14943 - 14945
Journal Article
Cell, ISSN 0092-8674, 09/2008, Volume 134, Issue 5, pp. 877 - 886
Journal Article
TRENDS IN GENETICS, ISSN 0168-9525, 02/2005, Volume 21, Issue 2, pp. 93 - 102
Microarrays provide the opportunity to measure transcription from regions of the genome without bias towards the location of known genes. This technology thus... 
OLIGONUCLEOTIDE ARRAYS | GENE | NONCODING RNAS | ANTISENSE TRANSCRIPTS | HUMAN-CHROMOSOME-21 | SEQUENCE | GENETICS & HEREDITY | CHROMOSOME-22 | FUNCTIONAL ANNOTATION | IDENTIFICATION | YEAST GENOME
Journal Article
NATURE BIOTECHNOLOGY, ISSN 1087-0156, 11/2005, Volume 23, Issue 11, pp. 1383 - 1390
In contrast to the fairly reliable and complete annotation of the protein coding genes in the human genome, comparable information is lacking for noncoding... 
MESSENGER-RNAS | SEQUENCES | TRANSCRIPTOME | SELECTIVE CONSTRAINT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | COMPUTATIONAL IDENTIFICATION | ULTRACONSERVED ELEMENTS | ESCHERICHIA-COLI | MOUSE | GENES | HUMAN-CHROMOSOME-21
Journal Article
Trends in Genetics, ISSN 0168-9525, 2006, Volume 22, Issue 1, pp. 1 - 5
The mammalian transcriptome contains many non-protein-coding RNAs (ncRNAs), but most of these are of unclear significance and lack strong sequence... 
MESSENGER-RNAS | CAENORHABDITIS-ELEGANS | GENE | MOUSE | HUMAN-CHROMOSOME-21 | GENETICS & HEREDITY | TILING ARRAYS | HUMAN TRANSCRIPTOME | IDENTIFICATION | EXPRESSION | GENOME | Animals | Humans | Conserved Sequence | Mice | MicroRNAs - genetics | RNA, Untranslated - genetics | RNA, Small Nucleolar - genetics | Evolution, Molecular | Genetic research | Analysis
Journal Article
Nature Communications, ISSN 2041-1723, 07/2015, Volume 6, Issue 1, p. 7550
The frequency of chromosome segregation errors during meiosis I (MI) in oocytes increases with age. The two-hit model suggests that errors are caused by the... 
MATERNAL AGE | ANEUPLOIDY | PREDIVISION | MECHANISM | MULTIDISCIPLINARY SCIENCES | FEMALE MEIOSIS | NONDISJUNCTION | MICE | 1ST POLAR BODIES | CHROMOSOME-21 | CHROMATIDS | Chromosome Segregation | Crossing Over, Genetic | Age Factors | Humans | Kinetochores | Aneuploidy | Meiosis | Time-Lapse Imaging | Oocytes | Mice, Knockout | Animals | Chromatids | Female | Mice
Journal Article
EUROPEAN JOURNAL OF HAEMATOLOGY, ISSN 0902-4441, 05/2013, Volume 90, Issue 5, pp. 404 - 412
Background The prognosis of acute lymphoblastic leukemia is poorer in adults than in children. Studies have indicated that young adults benefit from pediatric... 
YOUNG-ADULTS | adolescents | STANDARD-RISK | adults | PROGNOSTIC INFORMATION | TRIAL | acute lymphoblastic leukemia | children | INTRACHROMOSOMAL AMPLIFICATION | pediatric protocol | minimal residual disease | CHROMOSOME-21 | STEM-CELL TRANSPLANTATION | HEMATOLOGY | MRD
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 01/2018, Volume 36, Issue 1, pp. 34 - 43
Purpose Minimal residual disease (MRD) and genetic abnormalities are important risk factors for outcome in acute lymphoblastic leukemia. Current risk... 
RELAPSE | THERAPY | PROGNOSTIC-FACTORS | ONCOLOGY | INTRACHROMOSOMAL AMPLIFICATION | STANDARD-RISK | UKALL 2003 | RANDOMIZED CONTROLLED-TRIAL | CHROMOSOME-21 | INTENSIFICATION | CHILDRENS ONCOLOGY GROUP | ORIGINAL REPORTS
Journal Article
PLOS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12
Down's syndrome (DS) is a developmental disorder associated with intellectual disability (ID). We have previously shown that people with DS engage in very low... 
OBESITY | METABOLISM | GENE | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | CHROMOSOME-21 TRISOMY | PRECURSOR PROTEIN | DYSFUNCTION | EXPRESSION | EXERCISE | BRAINS
Journal Article
by P. Carninci and T. Kasukawa and S. Katayama and J. Gough and M. C. Frith and N. Maeda and R. Oyama and T. Ravasi and B. Lenhard and C. Wells and R. Kodzius and K. Shimokawa and V. B. Bajic and S. E. Brenner and S. Batalov and A. R. R. Forrest and M. Zavolan and M. J. Davis and L. G. Wilming and V. Aidinis and J. E. Allen and A. Ambesi-Impiombato and R. Apweiler and R. N. Aturaliya and T. L. Bailey and M. Bansal and L. Baxter and K. W. Beisel and T. Bersano and H. Bono and A. M. Chalk and K. P. Chiu and V. Choudhary and A. Christoffels and D. R. Clutterbuck and M. L. Crowe and E. Dalla and B. P. Dalrymple and B. de Bono and G. Della Gatta and D. di Bernardo and T. Down and P. Engstrom and M. Fagiolini and G. Faulkner and C. F. Fletcher and T. Fukushima and M. Furuno and S. Futaki and M. Gariboldi and P. Georgii-Hemming and T. R. Gingeras and T. Gojobori and R. E. Green and S. Gustincich and M. Harbers and Y. Hayashi and T. K. Hensch and N. Hirokawa and D. Hill and L. Huminiecki and M. Iacono and K. Ikeo and A. Iwama and T. Ishikawa and M. Jakt and A. Kanapin and M. Katoh and Y. Kawasawa and J. Kelso and H. Kitamura and H. Kitano and G. Kollias and S. P. T. Krishnan and A. Kruger and S. K. Kummerfeld and I. V. Kurochkin and L. F. Lareau and D. Lazarevic and L. Lipovich and J. Liu and S. Liuni and S. McWilliam and M. Madan Babu and M. Madera and L. Marchionni and H. Matsuda and S. Matsuzawa and H. Miki and F. Mignone and S. Miyake and K. Morris and S. Mottagui-Tabar and N. Mulder and N. Nakano and H. Nakauchi and P. Ng and R. Nilsson and S. Nishiguchi and S. Nishikawa and ... and RIKEN Genome Explorat Res Grp S and FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and The FANTOM Consortium and Institutionen för fysik, kemi och biologi and Biologiska Beräkningar and Linköpings universitet and Tekniska högskolan
Science, ISSN 0036-8075, 9/2005, Volume 309, Issue 5740, pp. 1559 - 1563
Journal Article
Science, ISSN 0036-8075, 4/2007, Volume 316, Issue 5824, pp. 608 - 611
Journal Article
Genome Biology, ISSN 1474-7596, 11/2009, Volume 10, Issue 11, pp. R124 - R124
Journal Article