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Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3387 - 3391
Addictive diseases, including addiction to heroin, prescription opioids, or cocaine, pose massive personal and public health costs. Addictions are chronic... 
STEADY-STATE METHADONE | FREELY MOVING RATS | MEDICINE, RESEARCH & EXPERIMENTAL | IN-VIVO MICRODIALYSIS | CORTICOTROPIN-RELEASING-FACTOR | MU-OPIOID-RECEPTOR | CHRONIC BINGE COCAINE | HPA-AXIS ACTIVATION | SINGLE-NUCLEOTIDE POLYMORPHISM | METHADONE-MAINTENANCE TREATMENT | MESSENGER-RNA LEVELS | Opioid-Related Disorders - drug therapy | Humans | Methadone - therapeutic use | Stress, Physiological | Cocaine-Related Disorders - genetics | Cocaine-Related Disorders - physiopathology | Neuropeptides - physiology | Receptors, Dopamine - drug effects | Receptors, Opioid - physiology | Dopamine - physiology | Opioid-Related Disorders - genetics | Dopaminergic Neurons - physiology | Limbic System - physiopathology | Hypothalamo-Hypophyseal System - physiopathology | Receptors, Dopamine - physiology | Limbic System - drug effects | Genetic Predisposition to Disease | Pharmacogenetics | Pituitary-Adrenal System - physiopathology | Basal Ganglia - physiopathology | Receptors, Opioid, mu - drug effects | Rats | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Cocaine-Related Disorders - drug therapy | Mice | Opioid-Related Disorders - physiopathology | Receptors, Opioid, mu - genetics | Reward | Receptors, Dopamine - genetics | Receptors, Opioid - drug effects | Basal Ganglia - drug effects | Receptors, Opioid, mu - physiology | Stress, Psychological - physiopathology | Messenger RNA | Opioids | Physiological aspects | Cocaine | Research | Health aspects | Sensory adaptation | Science in Medicine
Journal Article
Addiction Biology, ISSN 1355-6215, 07/2015, Volume 20, Issue 4, pp. 756 - 772
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 01/2010, Volume 35, Issue 2, pp. 505 - 514
A growing body of evidence indicates that protracted use of methamphetamine (mAMPH) causes long-term impairments in cognitive function in humans. Aside from... 
Compulsivity | Inhibitory control | Reversal, attentional set shifting | Behavioral flexibility | Psychostimulants | psychostimulants | PSYCHIATRY | inhibitory control | CHRONIC AMPHETAMINE | compulsivity | NEUROTOXICITY | NEUROSCIENCES | PREFRONTAL CORTEX | behavioral flexibility | reversal | SENSITIZING REGIMEN | DRUG-ADDICTION | NEURAL SYSTEMS | attentional set shifting | OBJECT RECOGNITION | PHARMACOLOGY & PHARMACY | RECOGNITION MEMORY | DEFICITS | ORBITOFRONTAL CORTEX | Dopamine Plasma Membrane Transport Proteins - metabolism | Reversal Learning - drug effects | Cocaine - metabolism | Methamphetamine - adverse effects | Body Temperature - drug effects | Rats, Long-Evans | Male | Corpus Striatum - metabolism | Learning Disorders - pathology | Radiopharmaceuticals - metabolism | Central Nervous System Stimulants - adverse effects | Protein Binding - drug effects | Attention - drug effects | Discrimination (Psychology) - drug effects | Dopamine - metabolism | Disease Models, Animal | Rats | Cocaine - analogs & derivatives | Neuropsychological Tests | Learning Disorders - chemically induced | Animals | Recognition (Psychology) - drug effects | Analysis of Variance | Photic Stimulation - methods | Radionuclide Imaging | Corpus Striatum - drug effects | Learning Disorders - metabolism | Corpus Striatum - diagnostic imaging | reversal, attentional set shifting | Original
Journal Article
Brain Research, ISSN 0006-8993, 2003, Volume 964, Issue 2, pp. 187 - 199
Tolerance to the stimulatory effects of cocaine on the hypothalamic–pituitary–adrenal (HPA) axis develops after chronic ‘binge’ cocaine exposure in the rat.... 
POMC | Chronic ‘binge’ cocaine | Corticosterone | Hypothalamic–pituitary–adrenal axis | ACTH | Anterior pituitary | CRH-R1 | Cocaine withdrawal | Hypothalamic-pituitary-adrenal axis | Chronic 'binge' cocaine | hypothalamic-pituitary-adrenal axis | ACTH-SECRETION | BETA-ENDORPHIN LEVELS | anterior pituitary | ANTERIOR-PITUITARY | PRIMARY-CELL CULTURES | chronic 'binge' cocaine | NEUROSCIENCES | NEUROENDOCRINE RESPONSES | PLASMA-CORTICOSTERONE | cocaine withdrawal | RNA LEVELS | MESSENGER-RIBONUCLEIC-ACID | EXTRACELLULAR LEVELS | GENE-EXPRESSION | corticosterone | Amygdala - drug effects | Receptors, Corticotropin-Releasing Hormone - metabolism | Frontal Lobe - metabolism | Pituitary Gland - metabolism | Enkephalins - metabolism | Rats, Inbred F344 | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Receptors, Corticotropin-Releasing Hormone - drug effects | RNA, Messenger - metabolism | Substance Withdrawal Syndrome - metabolism | Time Factors | Radioimmunoassay | Adrenal Glands - drug effects | Adrenocorticotropic Hormone - metabolism | Hypothalamo-Hypophyseal System - drug effects | Dopamine Uptake Inhibitors - pharmacology | Pituitary-Adrenal System - drug effects | Pituitary-Adrenal System - metabolism | Amygdala - metabolism | Rats | Corticotropin-Releasing Hormone - drug effects | Corticotropin-Releasing Hormone - metabolism | Hypothalamo-Hypophyseal System - metabolism | Dopamine Uptake Inhibitors - administration & dosage | Protein Precursors - metabolism | Pro-Opiomelanocortin - metabolism | Cocaine - administration & dosage | Cocaine - pharmacology | Blotting, Northern | Animals | Adrenal Glands - metabolism | Frontal Lobe - drug effects | Corticosterone - metabolism | Pro-Opiomelanocortin - drug effects | Pituitary Gland - drug effects
Journal Article
Addiction Biology, ISSN 1355-6215, 03/2012, Volume 17, Issue 2, pp. 365 - 377
Journal Article
Physiology & Behavior, ISSN 0031-9384, 2012, Volume 107, Issue 2, pp. 231 - 242
Abstract Positive reinforcement (e.g., appetitive, rewarding properties) has often been hypothesized to maintain excessive intake of palatable foods. Recently,... 
Psychiatry | Obesity | Surinabant or rimonabant | Binge eating | Sucrose or sugar or fat or food addiction | Corticotropin-releasing factor or corticotropin-releasing hormone or CRF or CRH | Endocannabinoid or cannabinoid type 1 receptor | Palatable food intake | Withdrawal anxiety | ANXIETY | FOOD-ANTICIPATORY ACTIVITY | COCAINE | CHRONIC STRESS | PALATABLE FOOD | CANNABINOID RECEPTOR | DEPRIVATION | BEHAVIORAL SCIENCES | PSYCHOLOGY, BIOLOGICAL | INDUCED INCREASES | CONDITIONED FLAVOR PREFERENCES | DARK SIDE | Pyrazoles - therapeutic use | Bulimia - physiopathology | Rats, Wistar | Bulimia - psychology | Motor Activity - drug effects | Bulimia - drug therapy | Dose-Response Relationship, Drug | Piperidines - pharmacology | Cannabinoid Receptor Antagonists - pharmacology | Female | Disease Models, Animal | Pyrazoles - pharmacology | Dietary Fats - adverse effects | Anxiety - psychology | Rats | Bulimia - chemically induced | Pyrimidines - pharmacology | Bulimia - blood | Maze Learning - drug effects | Cannabinoid Receptor Antagonists - therapeutic use | Receptors, Corticotropin-Releasing Hormone - physiology | Animals | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Piperidines - therapeutic use | Pyrimidines - therapeutic use | Dietary Sucrose - adverse effects | Anxiety - chemically induced | Corticosterone - metabolism
Journal Article