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2005, Current topics in microbiology and immunology, ISBN 3540252797, Volume 294., vi, 189
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of... 
Lymphocytic leukemia | Hematology | Cancer Research | Biomedicine
Book
2004, Hematology/oncology clinics of North America, Volume 18, no. 4., xv p., p. [783]-949
Book
The New England Journal of Medicine, ISSN 0028-4793, 01/2016, Volume 374, Issue 4, pp. 311 - 322
An oral inhibitor of BCL2 produces substantial responses in the majority of patients with refractory chronic lymphocytic leukemia. The agent is so effective... 
DOSE-ESCALATION | APOPTOSIS | MEDICINE, GENERAL & INTERNAL | CLL | INTERNATIONAL WORKSHOP | CYCLOPHOSPHAMIDE | RITUXIMAB | IBRUTINIB | INHIBITOR | PHASE-I | FLUDARABINE | Recurrence | Humans | Middle Aged | Male | Bridged Bicyclo Compounds, Heterocyclic - administration & dosage | Antineoplastic Agents - administration & dosage | Remission Induction | Sulfonamides - pharmacokinetics | Dose-Response Relationship, Drug | Disease-Free Survival | Bridged Bicyclo Compounds, Heterocyclic - adverse effects | Tumor Lysis Syndrome - etiology | Antineoplastic Agents - adverse effects | Aged, 80 and over | Sulfonamides - adverse effects | Adult | Female | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Aged | Antineoplastic Agents - pharmacokinetics | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Sulfonamides - administration & dosage | Bridged Bicyclo Compounds, Heterocyclic - pharmacokinetics | Antimitotic agents | Treatment outcome | Care and treatment | Usage | Safety and security measures | Lymphocytic leukemia | Analysis | Clinical trials | Dosage and administration | Antineoplastic agents | Pharmacokinetics | Risk factors | Flow cytometry | Chronic lymphatic leukemia | Cell survival | Leukemia | Minimal residual disease | Diarrhea | Chromosome deletion | Nausea | Lymphatic leukemia | Lymphoma | Patients | Proteins | Chemotherapy | Fludarabine | Clonal deletion | Lysis | Respiratory tract diseases | Lymphomas | Chromosome 17 | Neutropenia | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2015, Volume 373, Issue 25, pp. 2425 - 2437
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2014, Volume 370, Issue 11, pp. 997 - 1007
Journal Article
04/2019, ISBN 9783030113919, 171
eBook
The New England Journal of Medicine, ISSN 0028-4793, 07/2013, Volume 369, Issue 1, pp. 32 - 42
Ibrutinib inhibits Bruton's tyrosine kinase, a component of normal B-cell activation pathways. Ibrutinib produced responses in 71% of patients with refractory... 
MEDICINE, GENERAL & INTERNAL | BRUTONS TYROSINE KINASE | ACTIVATION | RITUXIMAB | B-CELL MALIGNANCIES | PCI-32765 | SURVIVAL SIGNALS | KAPPA-B | INHIBITOR | ANTIGEN RECEPTOR | FLUDARABINE | Recurrence | Pyrazoles - therapeutic use | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Pyrazoles - pharmacokinetics | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Treatment Outcome | Pyrimidines - pharmacology | Remission Induction | Disease-Free Survival | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Pyrimidines - pharmacokinetics | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Protein-Tyrosine Kinases - antagonists & inhibitors | Antimitotic agents | Chronic lymphocytic leukemia | Care and treatment | Product development | Antineoplastic agents | Tyrosine | Cell proliferation | Pharmacodynamics | Chronic lymphatic leukemia | Cell survival | Risk groups | Leukemia | Diarrhea | Fatigue | Lymphatic leukemia | Kinases | Lymphoma | Bruton's tyrosine kinase | Patients | Risk factors | Cell adhesion & migration | Clonal deletion | Lymphocytes B | Respiratory tract diseases | Lymphomas | Pharmacokinetics | Lymphocytosis | Protein-tyrosine kinase | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
2013, Advances in experimental medicine and biology, ISBN 9781461480518, Volume 792
Web Resource
2013, Advances in Experimental Medicine and Biology, ISBN 9781461480518, Volume 792.
Web Resource
The New England Journal of Medicine, ISSN 0028-4793, 12/2011, Volume 365, Issue 26, pp. 2497 - 2506
Journal Article