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Annals of Medicine, ISSN 0785-3890, 2006, Volume 38, Issue 2, pp. 116 - 125
Airway mucus hypersecretion is now recognized as a key pathophysiological feature in many patients with asthma, chronic obstructive pulmonary disease (COPD)... 
protease | protease inhibitor | mucin | chronic bronchitis | epidermal growth factor | MUC gene | Asthma | chronic obstructive pulmonary disease | COPD | Epidermal growth factor | Mucin | Protease | Chronic obstructive pulmonary disease | Chronic bronchitis | Protease inhibitor | CHRONIC-BRONCHITIS | INTRALUMINAL MUCUS | MUCIN GENE-EXPRESSION | asthma | MUCOCILIARY CLEARANCE | PERIPHERAL AIRWAYS | MEDICINE, GENERAL & INTERNAL | OBSTRUCTIVE PULMONARY-DISEASE | RETINOIC ACID | STATUS-ASTHMATICUS | GOBLET CELL HYPERPLASIA | RESPIRATORY MUCINS | Asthma - metabolism | Anti-Asthmatic Agents - therapeutic use | Myristoylated Alanine-Rich C Kinase Substrate | Humans | Respiratory System Agents - therapeutic use | Goblet Cells - drug effects | Receptors, Purinergic P2Y2 | Bronchitis, Chronic - metabolism | Drug Design | Mucins - metabolism | Anti-Inflammatory Agents - therapeutic use | Mucus - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Protease Inhibitors - therapeutic use | Lung - pathology | Goblet Cells - secretion | Mucin 5AC | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Purinergic P2 Receptor Antagonists | Purinergic P2 Receptor Agonists | Mucins - antagonists & inhibitors | Asthma - drug therapy | Bronchitis, Chronic - drug therapy | Neurotransmitter Agents - therapeutic use | Membrane Proteins - antagonists & inhibitors | Lung - drug effects | Mucus - chemistry | Goblet Cells - pathology | Lung - secretion | Pulmonary Disease, Chronic Obstructive - drug therapy
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 03/2018, Volume 58, Issue 3, pp. 299 - 309
Journal Article
European Respiratory Journal, ISSN 0903-1936, 10/2014, Volume 44, Issue 4, pp. 1002 - 1010
Journal Article
by Dijkstra, Akkelies E and Smolonska, Joanna and van den Berge, Maarten and Wijmenga, Ciska and Zanen, Pieter and Luinge, Marjan A and Platteel, Mathieu and Lammers, Jan-Willem and Dahlback, Magnus and Tosh, Kerrie and Hiemstra, Pieter S and Sterk, Peter J and Spira, Avi and Vestbo, Jorgen and Nordestgaard, Borge G and Benn, Marianne and Nielsen, Sune F and Dahl, Morten and Verschuren, W. Monique and Picavet, H. Susan J and Smit, Henriette A and Owsijewitsch, Michael and Kauczor, Hans U and de Koning, Harry J and Nizankowska-Mogilnicka, Eva and Mejza, Filip and Nastalek, Pawel and van Diemen, Cleo C and Cho, Michael H and Silverman, Edwin K and Crapo, James D and Beaty, Terri H and Lomas, David A and Bakke, Per and Gulsvik, Amund and Bossé, Yohan and Obeidat, M. A and Loth, Daan W and Lahousse, Lies and Rivadeneira, Fernando and Uitterlinden, Ane G and Hofman, Ane and Stricker, Bruno H and Brusselle, Guy G and van Duijn, Cornelia M and Brouwer, Uilke and Koppelman, Gerard H and Vonk, Judith M and Nawijn, Martijn C and Groen, Harry J. M and Timens, Wim and Boezen, H. Marike and Postma, Dirkje S and Alizadeh, B. Z and de Boer, R. A and Boezen, H. M and Bruinenberg, M and Franke, L and van der Harst, P and Hillege, H. L and van der Klauw, M. M and Navis, G and Ormel, J and Postma, D. S and Rosmalen, J. G. M and Slaets, J. P and Snieder, H and Stolk, R. P and Wolffenbuttel, B. H. R and Wijmenga, C and LifeLines Cohort Study and LifeLines Cohort study and the LifeLines Cohort study
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 4, p. e91621
Journal Article
Current Opinion in Pharmacology, ISSN 1471-4892, 2004, Volume 4, Issue 3, pp. 241 - 250
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, p. e0143526
Mucus hypersecretion is an important pathological feature of chronic airway diseases, such as asthma and pulmonary diseases. MUC5AC is a major component of the... 
LUNG | UNFOLDED PROTEIN RESPONSE | MECHANISM | ER STRESS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | HUMAN HEALTH | DISEASE | ASTHMA | MUC5AC GENE-EXPRESSION | COPD | Cell Line | Unfolded Protein Response - drug effects | Immunization | Respiratory Mucosa - drug effects | Endoplasmic Reticulum Stress - drug effects | Endoribonucleases - metabolism | Ovalbumin - immunology | Humans | Hyperplasia | TNF Receptor-Associated Factor 2 - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Mucus - secretion | Goblet Cells - metabolism | Respiratory Mucosa - pathology | Transforming Growth Factor beta - pharmacology | Animals | Signal Transduction - drug effects | Respiratory Mucosa - immunology | Kaempferols - pharmacology | Mice | Goblet Cells - pathology | Respiratory Mucosa - metabolism | Protein-Serine-Threonine Kinases - metabolism | Care and treatment | Rats as laboratory animals | Epithelial cells | Physiological aspects | Smooth muscle | Mucus | Research | Diagnosis | Endoplasmic reticulum | Risk factors | Asthma | Disease | Pathogenesis | Tunicamycin | mRNA | Activation | Chaperones | Kinases | Mucous membrane | Proteins | Signal transduction | Rodents | Animal tissues | Respiratory tract diseases | Chronic obstructive pulmonary disease | Inhibition | Growth factors | Food | Chronic illnesses | Stresses | Ovalbumin | Cytokines | Nutrition | Splicing | Secretion | Kaempferol | Lung diseases | Oral administration | JNK protein | Inflammation | Hsp70 protein | Pharmacology | Gene expression | Chemical compounds | Stress | Allergies | Diseases | TRAF2 protein | Mucins | In vivo methods and tests | Apoptosis | Respiratory tract
Journal Article