X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
ciap1 (191) 191
index medicus (121) 121
humans (114) 114
apoptosis (100) 100
activation (68) 68
inhibitor of apoptosis proteins - metabolism (66) 66
animals (58) 58
biochemistry & molecular biology (58) 58
cell biology (56) 56
cancer (54) 54
nf-kappa-b (49) 49
proteins (47) 47
cell line, tumor (45) 45
xiap (45) 45
oncology (44) 44
ubiquitination (44) 44
mice (43) 43
signal transduction (39) 39
apoptosis - drug effects (38) 38
alpha-dependent apoptosis (37) 37
inhibitor of apoptosis proteins - genetics (36) 36
inhibitor (32) 32
cell death (28) 28
ciap2 (28) 28
female (27) 27
inhibitor of apoptosis proteins - antagonists & inhibitors (27) 27
death (26) 26
ubiquitin (25) 25
iap (24) 24
nf-kappa b - metabolism (24) 24
expression (23) 23
male (23) 23
tnf-alpha (22) 22
degradation (21) 21
complex (19) 19
iaps (19) 19
cell-death (18) 18
kappa-b activation (18) 18
structural basis (18) 18
binding (17) 17
iap proteins (17) 17
protein binding (17) 17
survivin (17) 17
antineoplastic agents - pharmacology (16) 16
article (16) 16
gene expression (16) 16
mitochondrial proteins - metabolism (16) 16
necrosis (16) 16
tumor necrosis factor-alpha - metabolism (16) 16
diablo protein (15) 15
tumor necrosis factor-alpha - pharmacology (15) 15
ubiquitin-protein ligases (15) 15
baculoviral iap repeat-containing 3 protein (14) 14
intracellular signaling peptides and proteins - metabolism (14) 14
kinases (14) 14
original (14) 14
rna interference (14) 14
smac/diablo (14) 14
target (14) 14
tnf (14) 14
tumor necrosis factor (14) 14
tumors (14) 14
ubiquitin-protein ligases - metabolism (14) 14
x-linked inhibitor (14) 14
apoptosis - physiology (13) 13
biological phenomena, cell phenomena, and immunity (13) 13
immunology (13) 13
nf-kappa b (13) 13
receptor-interacting protein serine-threonine kinases - metabolism (13) 13
research (13) 13
resistance (13) 13
rip1 (13) 13
antagonists induce (12) 12
caspase-8 (12) 12
cells (12) 12
gene (12) 12
iap protein (12) 12
inflammation (12) 12
nf-κb (12) 12
nuclear pore complex proteins - metabolism (12) 12
rna-binding proteins - metabolism (12) 12
smac (12) 12
smac mimetic (12) 12
traf2 (12) 12
adult (11) 11
blotting, western (11) 11
c-iap1 (11) 11
cancer-cells (11) 11
caspase 8 - metabolism (11) 11
cell line (11) 11
family (11) 11
hek293 cells (11) 11
original article (11) 11
receptor (11) 11
smac mimetics (11) 11
ubiquitin - metabolism (11) 11
xenograft model antitumor assays (11) 11
apoptosis - genetics (10) 10
biology (10) 10
biophysics (10) 10
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell Reports, ISSN 2211-1247, 05/2019, Volume 27, Issue 9, pp. 2679 - 2689.e3
Cellular inhibitor of apoptosis proteins cIAP1 and cIAP2 ubiquitinate nuclear factor κB (NF-κB)-inducing kinase (NIK) to suppress non-canonical NF-κB signaling... 
cIAP2 | NIK | cIAP1 | apoptosis | caspase-8
Journal Article
Journal of Biomolecular Structure and Dynamics, ISSN 0739-1102, 2019, pp. 1 - 10
Inhibitor of apoptosis proteins (IAPs) are important regulators of apoptosis, and protein targets for the development of anti-cancer drugs. Cellular inhibitor... 
MD simulation | dimerization | cIAP1 | conformational change
Journal Article
SCIENCE SIGNALING, ISSN 1945-0877, 08/2019, Volume 12, Issue 596
IL-17 produced by T(H)17 cells plays a central role in numerous protective and pathologic immune responses. In this issue of Science Signaling, Rizk et al.... 
ANTAGONISTS INDUCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CIAP1 | CELL BIOLOGY
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 08/2018, Volume 61, Issue 16, pp. 7314 - 7329
Inhibitor of apoptosis proteins (IAPs) are promising anticancer targets, given their roles in the evasion of apoptosis. Several peptidomimetic IAP antagonists,... 
POTENT | CHEMISTRY, MEDICINAL | SMALL-MOLECULE ANTAGONIST | SMAC MIMETICS | IAP PROTEINS | DISCOVERY | CIAP1
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2009, Volume 284, Issue 51, pp. 35906 - 35915
Tumor necrosis factor (TNF) receptor-associated factor-2 (TRAF2) binds to cIAP1 and cIAP2 (cIAP1/2) and recruits them to the cytoplasmic domain of several... 
MULTIPLE-MYELOMA | UBIQUITINATION | SURVIVAL | PROTEIN | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-DEPENDENT APOPTOSIS | DEGRADATION | RECEPTOR-ASSOCIATED FACTOR-2 | CIAP1 | SIGNALING COMPLEX | Mechanisms of Signal Transduction
Journal Article
M S-MEDECINE SCIENCES, ISSN 0767-0974, 05/2019, Volume 35, Issue 5, pp. 405 - 405
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2018, Volume 506, Issue 3, pp. 423 - 428
The two major isoforms of the profilin (Pfn) family of proteins in mammals are Pfn1 and Pfn2. Pfn1 is a universal actin cytoskeletal regulator, while Pfn2 is... 
cIAP1 | Ubiquitination | CHIP | Pfn1 | ROS | Pfn2 | Ubiquitin | Actin | Ligases | Heat shock proteins | Muscle proteins | Protein binding | Apoptosis
Journal Article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 11/2018, Volume 506, Issue 3, pp. 423 - 428
The two major isoforms of the profilin (Pfn) family of proteins in mammals are Pfn1 and Pfn2. Pfn1 is a universal actin cytoskeletal regulator, while Pfn2 is... 
SURVIVAL | Ubiquitination | CHIP | BIOPHYSICS | C-TERMINUS | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ROS | cIAP1 | Pfn1 | Pfn2 | MOTILITY
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2009, Volume 36, Issue 2, pp. 302 - 314
Lysine-63 (K63)-linked polyubiquitination has emerged as a mechanism regulating diverse cellular functions, including activation of the protein kinase IKK in... 
PROTEINS | MOLIMMUNO | SIGNALING | APOPTOSIS | PROTEIN | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CONJUGATING ENZYME | REQUIRES | POLYUBIQUITIN CHAINS | NF-KAPPA-B | NEMO | CIAP1 | DROSOPHILA | CELL BIOLOGY
Journal Article
FASEB Journal, ISSN 0892-6638, 08/2009, Volume 23, Issue 8, pp. 2759 - 2771
Identifying the molecular mechanisms activated in compensatory hypertrophy and absent during decompensation will provide molecular targets for prevention of... 
NF-κB | cIAP1 | Pressure overload | Research Communications | pressure overload
Journal Article
Journal Article
European Respiratory Journal, ISSN 0903-1936, 05/2010, Volume 35, Issue 5, pp. 1155 - 1163
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 03/2010, Volume 17, Issue 3, pp. 482 - 487
On TNF binding, receptor-interacting protein kinase 1 (RIPK1) is recruited to the cytoplasmic domain of TNFR1, at which it becomes ubiquitylated and serves as... 
NF-κB | CHX | RIPK1 | TNF | CIAP1 | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | cIAP1 | DEATH | TRAF2 | GAMMA-DEFICIENT MICE | FACTOR RECEPTOR | SIGNALING COMPLEX | CELL BIOLOGY | TUMOR-NECROSIS-FACTOR | NF-kappa B | ALPHA-DEPENDENT APOPTOSIS | TNF-ALPHA | NEMO
Journal Article
Immunity, ISSN 1074-7613, 02/2012, Volume 36, Issue 2, pp. 215 - 227
Journal Article
Anticancer Research, ISSN 0250-7005, 11/2017, Volume 37, Issue 11, pp. 6097 - 6106
Journal Article