X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
cilengitide (213) 213
index medicus (113) 113
humans (112) 112
oncology (97) 97
angiogenesis (87) 87
integrins (82) 82
cancer (55) 55
glioblastoma (55) 55
animals (54) 54
integrin (50) 50
cell line, tumor (46) 46
expression (41) 41
pharmacology & pharmacy (36) 36
male (35) 35
apoptosis (32) 32
female (31) 31
brain neoplasms - drug therapy (30) 30
alpha-v-beta-3 (27) 27
alphabeta (27) 27
chemotherapy (26) 26
glioma (26) 26
metastasis (26) 26
peptides (26) 26
tumors (26) 26
cell biology (25) 25
mice (25) 25
temozolomide (24) 24
middle aged (23) 23
newly-diagnosed glioblastoma (23) 23
phase-i (23) 23
research (23) 23
cells (22) 22
snake venoms - therapeutic use (22) 22
aged (21) 21
growth (21) 21
malignant glioma (21) 21
adult (20) 20
snake venoms - pharmacology (20) 20
adhesion (19) 19
care and treatment (19) 19
clinical neurology (19) 19
integrin alphavbeta3 - metabolism (19) 19
radiotherapy (19) 19
antineoplastic agents - therapeutic use (18) 18
article (18) 18
chemistry, multidisciplinary (18) 18
glioblastoma - drug therapy (18) 18
glioma - drug therapy (18) 18
integrins - antagonists & inhibitors (18) 18
biochemistry & molecular biology (17) 17
clinical trials (17) 17
gliomas (17) 17
in-vivo (17) 17
ligands (17) 17
medicine & public health (17) 17
melanoma (17) 17
phase-ii (17) 17
cilengitide emd-121974 (16) 16
snake venoms - administration & dosage (16) 16
alphabeta integrin (15) 15
analysis (15) 15
aspartic acid peptide (15) 15
brain neoplasms - metabolism (15) 15
drug therapy (15) 15
health aspects (15) 15
open-label (15) 15
randomized phase-ii (15) 15
treatment outcome (15) 15
angiogenesis inhibitors - therapeutic use (14) 14
glioblastoma multiforme (14) 14
glioblastoma-multiforme (14) 14
integrin alphabeta (14) 14
integrins - metabolism (14) 14
medicine, research & experimental (14) 14
advanced solid tumors (13) 13
antagonists (13) 13
antineoplastic agents (13) 13
antineoplastic agents - pharmacology (13) 13
brain neoplasms - pathology (13) 13
endothelial growth-factor (13) 13
radiology, nuclear medicine & medical imaging (13) 13
tumor-growth (13) 13
antimitotic agents (12) 12
apoptosis - drug effects (12) 12
bevacizumab (12) 12
breast-cancer (12) 12
chemistry, medicinal (12) 12
integrin alphavbeta3 - antagonists & inhibitors (12) 12
migration (12) 12
monoclonal-antibody (12) 12
nanoparticles (12) 12
xenograft model antitumor assays (12) 12
aged, 80 and over (11) 11
angiogenesis inhibitors - pharmacology (11) 11
brain tumors (11) 11
carcinoma (11) 11
cell adhesion - drug effects (11) 11
development and progression (11) 11
gene expression (11) 11
glioblastoma - metabolism (11) 11
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


BLOOD, ISSN 0006-4971, 01/2015, Volume 125, Issue 5, pp. 841 - 851
The interaction of lymphoid tumor cells with components of the extracellular matrix via integrin alpha v beta 3 allows tumor survival and growth. This integrin... 
LYMPHOMA-CELLS | SUBTYPES | VEGF | GROWTH | PROLIFERATION | HEMATOLOGY | EXPRESSION | CANCER | CILENGITIDE
Journal Article
International Journal of Radiation Oncology Biology Physics, ISSN 0360-3016, 08/2006, Volume 65, Issue 5, pp. 1536 - 1543
Purpose: Integrins α β and α β are important in tumor growth and angiogenesis and have been recently explored as targets for cancer therapy. Radiotherapy also... 
Cilengitide | Integrin | Lung cancer | Endothelial cells | Radiation
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 01/2017, Volume 60, Issue 1, pp. 248 - 262
On the basis of a previously discovered anti-alpha(v)beta(3) integrin peptidomimetic (c(AmpRGD)) and the clinically approved antiangiogenic kinase inhibitor... 
VEGFR2 | RGD-PEPTIDE | CHEMISTRY, MEDICINAL | THERAPY | DRUG DISCOVERY | GROWTH | BIOLOGICAL EVALUATION | OPEN-LABEL | INHIBITORS | CANCER | CILENGITIDE
Journal Article
CURRENT OPINION IN CELL BIOLOGY, ISSN 0955-0674, 10/2016, Volume 42, pp. 121 - 127
Angiogenesis, the formation of new blood vessels from preexisting ones, is thought to enhance tumour growth and these blood vessels can act as conduits of... 
STANDARD TREATMENT | ANGIOGENESIS | ALPHA(V)BETA | RANDOMIZED PHASE-II | NEWLY-DIAGNOSED GLIOBLASTOMA | GROWTH | OPEN-LABEL | CANCER | EXPRESSION | CILENGITIDE | CELL BIOLOGY
Journal Article
by Noh, KW and Sohn, I and Song, JY and Shin, HT and Kim, YJ and Jung, K and Sung, M and Kim, M and An, S and Han, J and Lee, SH and Lee, MS and Choi, YL
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 09/2018, Volume 24, Issue 17, pp. 4162 - 4174
Purpose: Anaplastic lymphoma kinase (ALK)-positive cancers are sensitive to small-molecule ALK kinase inhibitors, but most cases experience failure following... 
CELL LUNG-CANCER | DISRUPTION | GENE | ONCOLOGY | RESISTANCE | PHASE-II | TALIN | KRAS | CHEMOTHERAPY | EGFR | CILENGITIDE
Journal Article
MOLECULAR CANCER RESEARCH, ISSN 1541-7786, 02/2019, Volume 17, Issue 2, pp. 398 - 408
The alpha(v)beta(3) integrin is involved in various physiologic and pathologic processes such as wound healing, angiogenesis, tumor growth, and metastasis. The... 
ADHESION | IN-VITRO | METASTASIS | INHIBITION | EFFICACY | ONCOLOGY | INDUCED APOPTOSIS | RADIOTHERAPY | EXPRESSION | MODULATION | CILENGITIDE | CELL BIOLOGY
Journal Article
BLOOD, ISSN 0006-4971, 04/2013, Volume 121, Issue 17, pp. 3307 - 3318
Acute graft-versus-host disease (GvHD) is a complex process involving endothelial damage and neovascularization. Better understanding of the pathophysiology of... 
RHEUMATOID-ARTHRITIS | INHIBITION | HEMATOPOIETIC-CELL TRANSPLANTATION | ANGIOGENESIS | GROWTH | MICROVASCULAR ENDOTHELIAL-CELLS | HYPOXIA | HEMATOLOGY | EXPRESSION | T-CELLS | CILENGITIDE
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2017, Volume 32, Issue 6, pp. 726 - 727
The link between GBM molecular subtype and response to treatment remains undefined. In this issue of , Cosset and colleagues define a subpopulation of patients... 
MALIGNANT GLIOMA | CELLS | ONCOLOGY | INTEGRIN | CILENGITIDE | CELL BIOLOGY | Addiction | Integrins
Journal Article
Journal Article
Journal Article
Drug Discovery Today, ISSN 1359-6446, 02/2017, Volume 22, Issue 2, pp. 454 - 462
Natural endogenously occurring peptides exhibit desirable medicinal properties, but are often limited in application by rapid proteolysis and inadequate... 
DESIGN | PROTEIN | AMINO-ACIDS | STABILITY | CROSS-LINKING | VASOPRESSIN | PHARMACOLOGY & PHARMACY | FUTURE | PEPTIDE | CILENGITIDE | STRATEGIES | Permeability | Lead compounds | Peptides | Therapeutics | Homeopathy | Materia medica and therapeutics | Medical colleges | Proteolysis | Isomerization
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 03/2015, Volume 136, Issue 6, pp. E545 - E558
During melanoma progression, tumour cells show increased adhesiveness to the vascular wall, invade the extracellular matrix (ECM) and frequently form... 
VEGFR2 | DESIGN | ANGIOGENESIS | vasculogenic mimicry | neuropilin 1 | melanoma | CANCER | TUMORS | BETA | ADHESION | integrins | cilengitide | PROMOTES INVASIVENESS | ONCOLOGY | GROWTH-FACTOR RECEPTOR-1
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 12/2018, Volume 16, Issue 1, pp. 352 - 13
To date the TGF-β1 activation mediated by integrin ανβ5 during fibrosis is well-known. This process has been shown also in the heart, where cardiac fibroblasts... 
Hypertension | Cilengitide | TGF-β1 | Integrin ανβ5 | Myofibroblast | Immunohistochemistry | Heart | Collagen (type I) | Collagens | Clinical trials | Smooth muscle | Activation | Tissues | Biomedical materials | Actin | Smad2 protein | Rodents | Fibroblasts | Extracellular matrix | Blood pressure | Inhibition | Cardiac muscle | Therapeutic applications | Muscles | Rats | Pharmacology | Collagen | Fibrosis | Differentiation
Journal Article
Analytical Chemistry, ISSN 0003-2700, 07/2015, Volume 87, Issue 13, pp. 6718 - 6723
We herein introduce a kind of fluorescent silicon nanoparticles (SiNPs) bioprobes, that is, peptides-conjugated SiNPs, which simultaneously feature small sizes... 
CLEARANCE | CHEMISTRY, ANALYTICAL | PHOTOLUMINESCENCE | THERAPY | NANOCRYSTALS | ULTRABRIGHT | TOXICITY | SCALE | LIVE CELLS | QUANTUM DOTS | CILENGITIDE | Nanoparticles | Peptides - chemistry | Neoplasms - pathology | Silicon - chemistry | Spectrophotometry, Ultraviolet | Humans | Usage | Peptides | Analysis | Optical properties | Cancer cells | Fluorescence | Probes (Electronic instruments) | Silicon | Research
Journal Article
European Journal of Cancer, ISSN 0959-8049, 05/2003, Volume 39, Issue 7, pp. 917 - 926
A single-agent dose escalating phase I and pharmacokinetic study with Cilengitide, an inhibitor of the integrins αvβ3 and αvβ5, was performed to determine its... 
Pharmacology | Cilengitide (EMD 121974) | Phase I clinical trial | Angiogenesis inhibitor | Integrins
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.