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JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 12/2002, Volume 110, Issue 11, pp. 1651 - 1658
Secretory diarrhea is the leading cause of infant death in developing countries and a major cause of morbidity in adults. The cystic fibrosis transmembrane... 
MEDICINE, RESEARCH & EXPERIMENTAL | CHLORIDE CURRENTS | CELLS | TRANSPORT | DIARRHEA | GENE | MOUSE MODEL | ENTEROTOXIN | CL CHANNEL | GLIBENCLAMIDE
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2018, Volume 115, Issue 21, pp. 5570 - 5575
In mammalian olfactory transduction, odorants activate a cAMP-mediated signaling pathway that leads to the opening of cyclic nucleotide-gated (CNG),... 
Cyclic nucleotide-gated channel | Olfactory receptor neurons | Ca2+-activated Cl channel | Olfactory transduction | Signal amplification
Journal Article
Journal of General Physiology, ISSN 0022-1295, 05/2013, Volume 141, Issue 5, pp. 585 - 600
Members of the TMEM16 (Anoctamin) family of membrane proteins have been shown to be essential constituents of the Ca2+-activated Cl- channel (CaCC) in many... 
PHYSIOLOGY | CHLORIDE CHANNELS | PROTEIN | CALCIUM | TRANSDUCTION | CURRENTS | CA2+-ACTIVATED CL-CHANNEL | EXPRESSION | CELL | MESSENGER | FAMILY
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 09/2015, Volume 40, Issue 9, pp. 535 - 543
For many years Cl transport by ion channels that are controlled by intracellular Ca or by cell volume remained enigmatic because their molecular identity was... 
CANCER-CELLS | ESSENTIAL COMPONENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | CALCIUM | CISPLATIN RESISTANCE | MEMBRANE-PROTEIN | REGULATED ANION CHANNEL | CA2+-ACTIVATED CL-CHANNEL | PLASMA-MEMBRANE | SENSORY NEURONS | ANOCTAMIN 6
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 08/2015, Volume 172, Issue 16, pp. 4158 - 4172
Background and PurposeT16A(inh)-A01, CaCCinh-A01 and MONNA are identified as selective inhibitors of the TMEM16A calcium-activated chloride channel (CaCC). The... 
CELLS | ANO1 | MESENTERIC SMALL ARTERIES | PROTEIN | PHARMACOLOGY & PHARMACY | PROLIFERATION | TMEM16A | CURRENTS | CA2+-ACTIVATED CL-CHANNEL | ARRIVE GUIDELINES | VASCULAR SMOOTH-MUSCLE
Journal Article
JOURNAL OF GENERAL PHYSIOLOGY, ISSN 0022-1295, 04/2019, Volume 151, Issue 4, pp. 518 - 531
Two TMEM16 family members, TMEM16A and TMEM16F, have different ion transport properties. Upon activation by intracellular Ca2+, TMEM16A-a Ca2+-activated Cl-... 
CIC-0 | PHYSIOLOGY | PROTEIN | CA2 | CALCIUM | PORE | INDEPENDENT ACTIVATION | CA2+-ACTIVATED CL-CHANNEL | EXPRESSION | Anions | Calcium (intracellular) | Lysine | Calcium channels (voltage-gated) | Amino acids | Ions | Cations | Phospholipids | Glutamine
Journal Article
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 05/2019, Volume 33, Issue 5, pp. 6632 - 6642
The Ca2+-activated Cl- channel, anoctamin 1 (Ano1, also known as transmembrane protein 16A) contributes to intestinal pacemaking, fluid secretion, cellular... 
gastrointestinal tract | CHLORIDE CHANNELS | MARKER | BIOCHEMISTRY & MOLECULAR BIOLOGY | calcium-activated chloride currents | PROLIFERATION | IDENTIFICATION | CANCER | ion channels | HEDGEHOG | INTERSTITIAL-CELLS | CELL BIOLOGY | INHIBITION | SNP | BIOLOGY | TMEM16A | CA2+-ACTIVATED CL-CHANNEL
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 1/2017, Volume 74, Issue 1, pp. 173 - 181
Activated receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like (MLKL) are essential components of the necroptotic pathway.... 
Life Sciences | Biomedicine, general | Biochemistry, general | TMEM16F | Anoctamin 6 | Life Sciences, general | Cell death | Necroptosis | Chloride channel | Cell Biology | Apoptosis | ANION CHANNEL | CHLORIDE CHANNELS | PROTEIN | ESSENTIAL COMPONENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | CL-CHANNEL | CELL BIOLOGY | NECROSIS | Index Medicus
Journal Article