Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 07/2012, Volume 67, Issue 7, pp. 1597 - 1606
OXA-48-type carbapenem-hydrolysing class D -lactamases are increasingly reported in enterobacterial species. To date, six OXA-48-like variants have been...
β-Lactamases | Carbapenems | Class D | Oxacillinases | NXL104 COMBINATIONS | INFECTIOUS DISEASES | ESCHERICHIA-COLI | MICROBIOLOGY | carbapenems | HYDROLYZING OXACILLINASE | FLIGHT MASS-SPECTROMETRY | DESORPTION IONIZATION-TIME | lactamases | OXA-48-PRODUCING ENTEROBACTERIACEAE | PHARMACOLOGY & PHARMACY | OXACILLINASE-MEDIATED RESISTANCE | oxacillinases | class D | D BETA-LACTAMASE | KLEBSIELLA-PNEUMONIAE | RAPID DETECTION | Carbapenems - metabolism | Enterobacteriaceae - enzymology | beta-Lactam Resistance | Prevalence | Global Health | Enterobacteriaceae Infections - microbiology | Humans | Bacterial Proteins - genetics | Enterobacteriaceae - genetics | Anti-Bacterial Agents - metabolism | Gene Transfer, Horizontal | Bacterial Proteins - secretion | beta-Lactamases - secretion | Hydrolysis | Enterobacteriaceae Infections - epidemiology | beta-Lactamases - genetics | Penicillins - metabolism | Plasmids | Enzymes | beta -Lactamase | Hospitals | Cephalosporins | Penicillin | Insertion sequences | Permeability | carbapenemase | Amino acid substitution
β-Lactamases | Carbapenems | Class D | Oxacillinases | NXL104 COMBINATIONS | INFECTIOUS DISEASES | ESCHERICHIA-COLI | MICROBIOLOGY | carbapenems | HYDROLYZING OXACILLINASE | FLIGHT MASS-SPECTROMETRY | DESORPTION IONIZATION-TIME | lactamases | OXA-48-PRODUCING ENTEROBACTERIACEAE | PHARMACOLOGY & PHARMACY | OXACILLINASE-MEDIATED RESISTANCE | oxacillinases | class D | D BETA-LACTAMASE | KLEBSIELLA-PNEUMONIAE | RAPID DETECTION | Carbapenems - metabolism | Enterobacteriaceae - enzymology | beta-Lactam Resistance | Prevalence | Global Health | Enterobacteriaceae Infections - microbiology | Humans | Bacterial Proteins - genetics | Enterobacteriaceae - genetics | Anti-Bacterial Agents - metabolism | Gene Transfer, Horizontal | Bacterial Proteins - secretion | beta-Lactamases - secretion | Hydrolysis | Enterobacteriaceae Infections - epidemiology | beta-Lactamases - genetics | Penicillins - metabolism | Plasmids | Enzymes | beta -Lactamase | Hospitals | Cephalosporins | Penicillin | Insertion sequences | Permeability | carbapenemase | Amino acid substitution
Journal Article
Clinical Microbiology Reviews, ISSN 0893-8512, 07/2007, Volume 20, Issue 3, pp. 440 - 458
Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit...
TRANSFERABLE IMIPENEM-RESISTANCE | EDTA DISK METHOD | GRAM-NEGATIVE BACTERIA | CLASS-A CARBAPENEMASE | PNEUMONIAE CARRYING BLA(VIM-1) | ANTIMICROBIAL SURVEILLANCE PROGRAM | MICROBIOLOGY | REPUBLIC-OF-CHINA | NATURALLY-OCCURRING OXACILLINASE | RESISTANT PSEUDOMONAS-AERUGINOSA | STANDARD NUMBERING SCHEME | Bacteria - metabolism | Enterobacteriaceae - enzymology | Global Health | Enterobacter cloacae - enzymology | Bacteria - drug effects | Bacterial Proteins - genetics | Bacteria - genetics | Hydrolysis | Microbial Sensitivity Tests | Enterobacteriaceae Infections - epidemiology | Klebsiella Infections - epidemiology | beta-Lactamases - classification | beta-Lactamases - genetics | Molecular Epidemiology | beta-Lactamases - analysis | Disease Outbreaks | Plasmids | Pseudomonas aeruginosa - enzymology | Klebsiella pneumoniae - enzymology | Bacteria - enzymology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - classification | beta-Lactamases - metabolism | Reviews
TRANSFERABLE IMIPENEM-RESISTANCE | EDTA DISK METHOD | GRAM-NEGATIVE BACTERIA | CLASS-A CARBAPENEMASE | PNEUMONIAE CARRYING BLA(VIM-1) | ANTIMICROBIAL SURVEILLANCE PROGRAM | MICROBIOLOGY | REPUBLIC-OF-CHINA | NATURALLY-OCCURRING OXACILLINASE | RESISTANT PSEUDOMONAS-AERUGINOSA | STANDARD NUMBERING SCHEME | Bacteria - metabolism | Enterobacteriaceae - enzymology | Global Health | Enterobacter cloacae - enzymology | Bacteria - drug effects | Bacterial Proteins - genetics | Bacteria - genetics | Hydrolysis | Microbial Sensitivity Tests | Enterobacteriaceae Infections - epidemiology | Klebsiella Infections - epidemiology | beta-Lactamases - classification | beta-Lactamases - genetics | Molecular Epidemiology | beta-Lactamases - analysis | Disease Outbreaks | Plasmids | Pseudomonas aeruginosa - enzymology | Klebsiella pneumoniae - enzymology | Bacteria - enzymology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - classification | beta-Lactamases - metabolism | Reviews
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2010, Volume 132, Issue 38, pp. 13320 - 13331
Class D β-lactamases represent a growing and diverse class of penicillin-inactivating enzymes that are usually resistant to commercial β-lactamase inhibitors....
CLASS-A | BETA-LACTAMASE INHIBITORS | BLAR1 PROTEIN | ESCHERICHIA-COLI | ANTIBIOTIC-RESISTANCE | OUTER-MEMBRANE PERMEABILITY | STAPHYLOCOCCUS-AUREUS | DIFFRACTION DATA | MECHANISTIC DIVERSITY | IONIZATION MASS-SPECTROMETRY | CHEMISTRY, MULTIDISCIPLINARY | Bacterial Proteins - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Crystallography, X-Ray | Enzyme Inhibitors - chemical synthesis | Sulfones - pharmacology | Acinetobacter baumannii - enzymology | Penicillanic Acid - chemistry | Microbial Sensitivity Tests | Spectrometry, Mass, Electrospray Ionization | Sulfones - chemistry | Enzyme Inhibitors - chemistry | beta-Lactamases | Molecular Structure | beta-Lactamase Inhibitors | Acinetobacter baumannii - drug effects | Sulfones - chemical synthesis | Analysis | Penicillin | Physiological aspects | Substitution reactions | Chemical properties | Structure | Staphylococcus aureus | Sulfones | CARBONYLS | DESIGN | INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY | HYDROLYSIS | CRYSTAL STRUCTURE | national synchrotron light source | MASS SPECTROSCOPY | SULFONES | SENSORS | INACTIVATION | OXYGEN | STAPHYLOCOCCUS | ENZYMES | PSEUDOMONAS | HYPOTHESIS | CHEMISTRY | SYNTHESIS | AROMATICS | EFFICIENCY | IONIZATION | RESIDUES | PENICILLIN | OXA carbapenemase | penicillin | β-lactamase inhibitor
CLASS-A | BETA-LACTAMASE INHIBITORS | BLAR1 PROTEIN | ESCHERICHIA-COLI | ANTIBIOTIC-RESISTANCE | OUTER-MEMBRANE PERMEABILITY | STAPHYLOCOCCUS-AUREUS | DIFFRACTION DATA | MECHANISTIC DIVERSITY | IONIZATION MASS-SPECTROMETRY | CHEMISTRY, MULTIDISCIPLINARY | Bacterial Proteins - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Crystallography, X-Ray | Enzyme Inhibitors - chemical synthesis | Sulfones - pharmacology | Acinetobacter baumannii - enzymology | Penicillanic Acid - chemistry | Microbial Sensitivity Tests | Spectrometry, Mass, Electrospray Ionization | Sulfones - chemistry | Enzyme Inhibitors - chemistry | beta-Lactamases | Molecular Structure | beta-Lactamase Inhibitors | Acinetobacter baumannii - drug effects | Sulfones - chemical synthesis | Analysis | Penicillin | Physiological aspects | Substitution reactions | Chemical properties | Structure | Staphylococcus aureus | Sulfones | CARBONYLS | DESIGN | INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY | HYDROLYSIS | CRYSTAL STRUCTURE | national synchrotron light source | MASS SPECTROSCOPY | SULFONES | SENSORS | INACTIVATION | OXYGEN | STAPHYLOCOCCUS | ENZYMES | PSEUDOMONAS | HYPOTHESIS | CHEMISTRY | SYNTHESIS | AROMATICS | EFFICIENCY | IONIZATION | RESIDUES | PENICILLIN | OXA carbapenemase | penicillin | β-lactamase inhibitor
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2010, Volume 36, Issue 3, pp. S8 - S14
Summary The celestial rise in antibiotic resistance among Gram-negative bacteria has challenged both the scientific and pharmaceutical sectors. The hallmark of...
Infectious Disease | Metallo-β-lactamases | Carbapenemases | Carbapenem resistance | UNITED-STATES | Metallo-beta-lactamases | CLASS 1 INTEGRONS | INFECTIOUS DISEASES | ESCHERICHIA-COLI | MICROBIOLOGY | SERRATIA-MARCESCENS | BACTERIAL PATHOGENS | METALLO-BETA-LACTAMASE | PSEUDOMONAS-AERUGINOSA | RESISTANT ACINETOBACTER-BAUMANNII | ANTIMICROBIAL SURVEILLANCE PROGRAM | PHARMACOLOGY & PHARMACY | KLEBSIELLA-PNEUMONIAE | Gram-Negative Bacteria - enzymology | Gram-Negative Bacterial Infections - microbiology | Drug Utilization - standards | beta-Lactam Resistance | Carbapenems - pharmacology | Prevalence | Humans | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - biosynthesis | beta-Lactamases - biosynthesis | Gram-Negative Bacteria - isolation & purification | Drug resistance in microorganisms | Beta lactamases
Infectious Disease | Metallo-β-lactamases | Carbapenemases | Carbapenem resistance | UNITED-STATES | Metallo-beta-lactamases | CLASS 1 INTEGRONS | INFECTIOUS DISEASES | ESCHERICHIA-COLI | MICROBIOLOGY | SERRATIA-MARCESCENS | BACTERIAL PATHOGENS | METALLO-BETA-LACTAMASE | PSEUDOMONAS-AERUGINOSA | RESISTANT ACINETOBACTER-BAUMANNII | ANTIMICROBIAL SURVEILLANCE PROGRAM | PHARMACOLOGY & PHARMACY | KLEBSIELLA-PNEUMONIAE | Gram-Negative Bacteria - enzymology | Gram-Negative Bacterial Infections - microbiology | Drug Utilization - standards | beta-Lactam Resistance | Carbapenems - pharmacology | Prevalence | Humans | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - biosynthesis | beta-Lactamases - biosynthesis | Gram-Negative Bacteria - isolation & purification | Drug resistance in microorganisms | Beta lactamases
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 03/2006, Volume 57, Issue 3, pp. 373 - 383
In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence...
Pseudomonas aeruginosa | Acinetobacter baumannii | Carbapenem resistance | Class D β-lactamases | INFECTIOUS DISEASES | class D beta-lactamases | BIOCHEMICAL-CHARACTERIZATION | MICROBIOLOGY | NATURALLY-OCCURRING OXACILLINASE | HYDROLYZING OXACILLINASE | carbapenem resistance | OUTER-MEMBRANE PROTEIN | PSEUDOMONAS-AERUGINOSA | IMIPENEM RESISTANCE | RESISTANT ACINETOBACTER-BAUMANNII | PENICILLIN-BINDING PROTEINS | PHARMACOLOGY & PHARMACY | D BETA-LACTAMASE | KLEBSIELLA-PNEUMONIAE | beta-Lactamases - classification | Drug Resistance, Bacterial | Anti-Bacterial Agents - metabolism | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - classification | beta-Lactamases - metabolism | Acinetobacter baumannii - enzymology
Pseudomonas aeruginosa | Acinetobacter baumannii | Carbapenem resistance | Class D β-lactamases | INFECTIOUS DISEASES | class D beta-lactamases | BIOCHEMICAL-CHARACTERIZATION | MICROBIOLOGY | NATURALLY-OCCURRING OXACILLINASE | HYDROLYZING OXACILLINASE | carbapenem resistance | OUTER-MEMBRANE PROTEIN | PSEUDOMONAS-AERUGINOSA | IMIPENEM RESISTANCE | RESISTANT ACINETOBACTER-BAUMANNII | PENICILLIN-BINDING PROTEINS | PHARMACOLOGY & PHARMACY | D BETA-LACTAMASE | KLEBSIELLA-PNEUMONIAE | beta-Lactamases - classification | Drug Resistance, Bacterial | Anti-Bacterial Agents - metabolism | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - classification | beta-Lactamases - metabolism | Acinetobacter baumannii - enzymology
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 9/2007, Volume 60, Issue 3, pp. 470 - 482
Carbapenems, such as imipenem and meropenem, are most often used to treat infections caused by enterobacteria that produce extended-spectrum β-lactamases, and...
Class A β-lactamases | Pseudomonas aeruginosa | Carbapenem resistance | Enterobacteriaceae | SPECTRUM-BETA-LACTAMASE | INFECTIOUS DISEASES | PSEUDOMONAS-AERUGINOSA STRAIN | BROAD SUBSTRATE-SPECIFICITY | RESISTANT KLEBSIELLA-PNEUMONIAE | MICROBIOLOGY | HYDROLYZING ENZYME KPC-2 | SERRATIA-MARCESCENS S6 | class a beta-lactamases | carbapenem resistance | OUTER-MEMBRANE PROTEIN | COLI CLINICAL ISOLATE | PENICILLIN-BINDING PROTEINS | ANTIMICROBIAL SURVEILLANCE PROGRAM | PHARMACOLOGY & PHARMACY | Bacterial Proteins - antagonists & inhibitors | Humans | Bacterial Proteins - genetics | Drug Resistance, Bacterial | Structure-Activity Relationship | Anti-Bacterial Agents - therapeutic use | Animals | Carbapenems - pharmacology | Serratia marcescens - genetics | beta-Lactamases - genetics | Carbapenems - therapeutic use | Klebsiella pneumoniae - enzymology | Klebsiella pneumoniae - genetics | Serratia marcescens - enzymology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamase Inhibitors | beta-Lactamases - metabolism | Enzymes | Bacteria | Genetics | Infections | Antibiotics | Drug resistance
Class A β-lactamases | Pseudomonas aeruginosa | Carbapenem resistance | Enterobacteriaceae | SPECTRUM-BETA-LACTAMASE | INFECTIOUS DISEASES | PSEUDOMONAS-AERUGINOSA STRAIN | BROAD SUBSTRATE-SPECIFICITY | RESISTANT KLEBSIELLA-PNEUMONIAE | MICROBIOLOGY | HYDROLYZING ENZYME KPC-2 | SERRATIA-MARCESCENS S6 | class a beta-lactamases | carbapenem resistance | OUTER-MEMBRANE PROTEIN | COLI CLINICAL ISOLATE | PENICILLIN-BINDING PROTEINS | ANTIMICROBIAL SURVEILLANCE PROGRAM | PHARMACOLOGY & PHARMACY | Bacterial Proteins - antagonists & inhibitors | Humans | Bacterial Proteins - genetics | Drug Resistance, Bacterial | Structure-Activity Relationship | Anti-Bacterial Agents - therapeutic use | Animals | Carbapenems - pharmacology | Serratia marcescens - genetics | beta-Lactamases - genetics | Carbapenems - therapeutic use | Klebsiella pneumoniae - enzymology | Klebsiella pneumoniae - genetics | Serratia marcescens - enzymology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamase Inhibitors | beta-Lactamases - metabolism | Enzymes | Bacteria | Genetics | Infections | Antibiotics | Drug resistance
Journal Article
EMERGING INFECTIOUS DISEASES, ISSN 1080-6040, 03/2012, Volume 18, Issue 3, pp. 523 - 525
BLA(OXA-23) | RESISTANCE | INFECTIOUS DISEASES | BAUMANNII | IMMUNOLOGY | Cattle Diseases - microbiology | Acinetobacter - classification | Acinetobacter - genetics | beta-Lactamases - biosynthesis | Molecular Typing | Microbial Sensitivity Tests | Animals | DNA Gyrase - genetics | Cattle | Acinetobacter Infections - veterinary | Acinetobacter - isolation & purification | Bacterial Proteins - biosynthesis | France | Acinetobacter Infections - microbiology | Drug resistance in microorganisms | Acinetobacter | Research | Carbapenems | Letter | carbapenem-hydrolyzing class D β-lactamases | OXA-23 | bacteria | Letters to the Editor | cattle | carbapenemase
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 02/2013, Volume 68, Issue 2, pp. 478 - 480
Antimicrobial resistance | Class 1 integrons | Carbapenems | Plasmids | INFECTIOUS DISEASES | antimicrobial resistance | INFANTIS | class 1 integrons | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | carbapenems | plasmids | Microbial Sensitivity Tests | beta-Lactam Resistance | beta-Lactams - pharmacology | Animals | beta-Lactamases - genetics | Salmonella Infections, Animal - microbiology | Salmonella enterica - enzymology | Salmonella enterica - genetics | Salmonella enterica - isolation & purification | Anti-Bacterial Agents - pharmacology | Livestock | beta-Lactamases - secretion
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2013, Volume 42, Issue 6, pp. 531 - 536
Abstract OXA-48 β-lactamase is one of the several emerging carbapenemases. Pre-2007 reports were almost exclusively from Turkey, but subsequently its...
Infectious Disease | Sequence type | Class D β-lactamase | Renal | Infection control | INFECTIOUS DISEASES | ESCHERICHIA-COLI | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | EMERGENCE | BETA-LACTAMASE | GENES | PHARMACOLOGY & PHARMACY | Class D beta-lactamase | RESISTANT KLEBSIELLA | SPREAD | RAPID DETECTION | PCR | Klebsiella pneumoniae - isolation & purification | Humans | Risk Factors | Genotype | Klebsiella pneumoniae - classification | Klebsiella Infections - microbiology | Multilocus Sequence Typing | Electrophoresis, Gel, Pulsed-Field | beta-Lactamases - secretion | Klebsiella Infections - epidemiology | Hospitals | Disease Outbreaks | Cross Infection - microbiology | Klebsiella pneumoniae - enzymology | Klebsiella pneumoniae - genetics | London - epidemiology | Cross Infection - epidemiology | Pneumonia | Oxalic acid | Bacterial pneumonia | Health care reform | Drug resistance | Health aspects
Infectious Disease | Sequence type | Class D β-lactamase | Renal | Infection control | INFECTIOUS DISEASES | ESCHERICHIA-COLI | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | EMERGENCE | BETA-LACTAMASE | GENES | PHARMACOLOGY & PHARMACY | Class D beta-lactamase | RESISTANT KLEBSIELLA | SPREAD | RAPID DETECTION | PCR | Klebsiella pneumoniae - isolation & purification | Humans | Risk Factors | Genotype | Klebsiella pneumoniae - classification | Klebsiella Infections - microbiology | Multilocus Sequence Typing | Electrophoresis, Gel, Pulsed-Field | beta-Lactamases - secretion | Klebsiella Infections - epidemiology | Hospitals | Disease Outbreaks | Cross Infection - microbiology | Klebsiella pneumoniae - enzymology | Klebsiella pneumoniae - genetics | London - epidemiology | Cross Infection - epidemiology | Pneumonia | Oxalic acid | Bacterial pneumonia | Health care reform | Drug resistance | Health aspects
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 07/2012, Volume 67, Issue 7, pp. 1793 - 1795
Livestock | Antimicrobial resistance | Class 1 integrons | Carbapenems | Plasmids | INFECTIOUS DISEASES | antimicrobial resistance | livestock | PLASMID | class 1 integrons | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | carbapenems | plasmids | Integrons | beta-Lactam Resistance | Escherichia coli - enzymology | Escherichia coli Infections - microbiology | Molecular Sequence Data | DNA, Bacterial - chemistry | Sequence Analysis, DNA | beta-Lactams - pharmacology | Animals | DNA, Bacterial - genetics | beta-Lactamases - genetics | Escherichia coli - isolation & purification | Swine | Swine Diseases - microbiology | Escherichia coli Infections - veterinary | Gene Order | Longitudinal Studies
Journal Article
Clinical Microbiology and Infection, ISSN 1198-743X, 09/2011, Volume 17, Issue 9, pp. 1438 - 1441
We evaluated the ability of the combination disk test (CDT) and the Modified Hodge Test (MHT) to discriminate between various carbapenemase-producing isolates...
Pseudomonas aeruginosa | 3-Aminophenylboronic acid | carbapenemase | dipicolinic acid | cloxacillin | 3‐Aminophenylboronic acid | Dipicolinic acid | Carbapenemase | Cloxacillin | INFECTIOUS DISEASES | CLASS-A CARBAPENEMASE | RESISTANCE | MICROBIOLOGY | KLEBSIELLA-PNEUMONIAE | ENTEROBACTERIACEAE | Disk Diffusion Antimicrobial Tests - methods | Picolinic Acids - pharmacology | Humans | beta-Lactamases - drug effects | Pseudomonas aeruginosa - drug effects | Thienamycins - pharmacology | Cloxacillin - pharmacology | Pseudomonas Infections - microbiology | Bacterial Proteins - drug effects | Pseudomonas aeruginosa - enzymology | Sensitivity and Specificity | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamases - metabolism | Pseudomonas aeruginosa - classification | Boronic Acids - pharmacology | Enzymes | Meropenem | Metallo- beta -lactamase
Pseudomonas aeruginosa | 3-Aminophenylboronic acid | carbapenemase | dipicolinic acid | cloxacillin | 3‐Aminophenylboronic acid | Dipicolinic acid | Carbapenemase | Cloxacillin | INFECTIOUS DISEASES | CLASS-A CARBAPENEMASE | RESISTANCE | MICROBIOLOGY | KLEBSIELLA-PNEUMONIAE | ENTEROBACTERIACEAE | Disk Diffusion Antimicrobial Tests - methods | Picolinic Acids - pharmacology | Humans | beta-Lactamases - drug effects | Pseudomonas aeruginosa - drug effects | Thienamycins - pharmacology | Cloxacillin - pharmacology | Pseudomonas Infections - microbiology | Bacterial Proteins - drug effects | Pseudomonas aeruginosa - enzymology | Sensitivity and Specificity | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamases - metabolism | Pseudomonas aeruginosa - classification | Boronic Acids - pharmacology | Enzymes | Meropenem | Metallo- beta -lactamase
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 05/2019, Volume 63, Issue 5
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 09/2015, Volume 59, Issue 9, pp. 5324 - 5330
Ceftazidime-avibactam is active against most Enterobacteriaceae isolates with KPC carbapenemases. We investigated whether this activity could be compromised by...
CLASS-A | INFECTIONS | MECHANISM | EFFICACY | ESCHERICHIA-COLI | EXPANSION | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | TEM-BETA-LACTAMASE | INHIBITOR | EXPRESSION | KLEBSIELLA-PNEUMONIAE | Azabicyclo Compounds - pharmacology | Microbial Sensitivity Tests | Enterobacteriaceae - enzymology | beta-Lactamases - genetics | Ceftazidime - pharmacology | Bacterial Proteins - genetics | Enterobacteriaceae - drug effects | Enterobacteriaceae - genetics | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamases - metabolism | Drug Resistance, Multiple, Bacterial - genetics | Mechanisms of Resistance
CLASS-A | INFECTIONS | MECHANISM | EFFICACY | ESCHERICHIA-COLI | EXPANSION | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | TEM-BETA-LACTAMASE | INHIBITOR | EXPRESSION | KLEBSIELLA-PNEUMONIAE | Azabicyclo Compounds - pharmacology | Microbial Sensitivity Tests | Enterobacteriaceae - enzymology | beta-Lactamases - genetics | Ceftazidime - pharmacology | Bacterial Proteins - genetics | Enterobacteriaceae - drug effects | Enterobacteriaceae - genetics | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamases - metabolism | Drug Resistance, Multiple, Bacterial - genetics | Mechanisms of Resistance
Journal Article
Annals of Laboratory Medicine, ISSN 2234-3806, 2015, Volume 35, Issue 2, pp. 212 - 219
Background: We evaluated the combined use of the modified Hodge test (MHT) and carbapenemase inhibition test (CIT) using phenylboronic acid (PBA) and EDTA to...
Phenylboronic acid | Pseudomonas spp | Carbapenemase inhibition test | EDTA | Modified hodge test | Enterobacteriaceae | CLASS-A CARBAPENEMASE | DIPICOLINIC ACID | SPP | Modified Hodge test | BORONIC ACID COMPOUNDS | ACINETOBACTER | MEDICAL LABORATORY TECHNOLOGY | KLEBSIELLA-PNEUMONIAE CARBAPENEMASES | STRAIN | KPC | Bacterial Proteins - antagonists & inhibitors | Disk Diffusion Antimicrobial Tests - methods | Enterobacteriaceae - enzymology | Enterobacteriaceae Infections - diagnosis | Humans | Pseudomonas Infections - diagnosis | Boronic Acids - chemistry | beta-Lactamases - chemistry | Edetic Acid - chemistry | Pseudomonas - drug effects | Pseudomonas - enzymology | Sensitivity and Specificity | Edetic Acid - pharmacology | Enterobacteriaceae - drug effects | Bacterial Proteins - metabolism | beta-Lactamases - metabolism | Boronic Acids - pharmacology | Original | 병리학
Phenylboronic acid | Pseudomonas spp | Carbapenemase inhibition test | EDTA | Modified hodge test | Enterobacteriaceae | CLASS-A CARBAPENEMASE | DIPICOLINIC ACID | SPP | Modified Hodge test | BORONIC ACID COMPOUNDS | ACINETOBACTER | MEDICAL LABORATORY TECHNOLOGY | KLEBSIELLA-PNEUMONIAE CARBAPENEMASES | STRAIN | KPC | Bacterial Proteins - antagonists & inhibitors | Disk Diffusion Antimicrobial Tests - methods | Enterobacteriaceae - enzymology | Enterobacteriaceae Infections - diagnosis | Humans | Pseudomonas Infections - diagnosis | Boronic Acids - chemistry | beta-Lactamases - chemistry | Edetic Acid - chemistry | Pseudomonas - drug effects | Pseudomonas - enzymology | Sensitivity and Specificity | Edetic Acid - pharmacology | Enterobacteriaceae - drug effects | Bacterial Proteins - metabolism | beta-Lactamases - metabolism | Boronic Acids - pharmacology | Original | 병리학
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2010, Volume 37, Issue 3, pp. 244 - 247
Abstract Antibiotic combinations including tigecycline have not been studied against Klebsiella pneumoniae carbapenemase (KPC)-producing pathogens. Tigecycline...
Infectious Disease | Class A carbapenemase | Synergistic | Colistin | Bacteriostatic | Bactericidal | Meropenem | Time–kill | Tigecycline | KPC | Time-kill | INFECTIOUS DISEASES | MICROBIOLOGY | THREAT | PHARMACOLOGY & PHARMACY | SPREAD | IN-VITRO ACTIVITY | Enterobacter cloacae - drug effects | Enterobacteriaceae - enzymology | Escherichia coli - enzymology | Klebsiella pneumoniae - drug effects | Serratia marcescens - drug effects | Enterobacter cloacae - enzymology | Minocycline - pharmacology | Enterobacteriaceae Infections - microbiology | Escherichia coli - drug effects | Humans | Minocycline - analogs & derivatives | Drug Resistance, Bacterial | Thienamycins - pharmacology | Microbial Sensitivity Tests | Colistin - pharmacology | Enterobacteriaceae - drug effects | Klebsiella pneumoniae - enzymology | Serratia marcescens - enzymology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamases - metabolism | Drug Combinations
Infectious Disease | Class A carbapenemase | Synergistic | Colistin | Bacteriostatic | Bactericidal | Meropenem | Time–kill | Tigecycline | KPC | Time-kill | INFECTIOUS DISEASES | MICROBIOLOGY | THREAT | PHARMACOLOGY & PHARMACY | SPREAD | IN-VITRO ACTIVITY | Enterobacter cloacae - drug effects | Enterobacteriaceae - enzymology | Escherichia coli - enzymology | Klebsiella pneumoniae - drug effects | Serratia marcescens - drug effects | Enterobacter cloacae - enzymology | Minocycline - pharmacology | Enterobacteriaceae Infections - microbiology | Escherichia coli - drug effects | Humans | Minocycline - analogs & derivatives | Drug Resistance, Bacterial | Thienamycins - pharmacology | Microbial Sensitivity Tests | Colistin - pharmacology | Enterobacteriaceae - drug effects | Klebsiella pneumoniae - enzymology | Serratia marcescens - enzymology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamases - metabolism | Drug Combinations
Journal Article
EMERGING INFECTIOUS DISEASES, ISSN 1080-6040, 01/2011, Volume 17, Issue 1, pp. 143 - 144
Class D OXA β-lactamases are characterized as penicillinases that can hydrolyze oxacillin and cloxacillin and are poorly inhibited by clavulanic acid and EDTA....
INFECTIOUS DISEASES | BETA-LACTAMASE | TURKEY | PLASMID | IMMUNOLOGY | SPREAD | KLEBSIELLA-PNEUMONIAE | Senegal - epidemiology | Enterobacteriaceae - enzymology | Communicable Diseases, Emerging - microbiology | Community-Acquired Infections - epidemiology | Enterobacteriaceae Infections - microbiology | Humans | Bacterial Proteins - genetics | Enterobacteriaceae - genetics | Communicable Diseases, Emerging - epidemiology | Microbial Sensitivity Tests | Enterobacteriaceae Infections - epidemiology | beta-Lactamases - genetics | Cross Infection - microbiology | Enterobacteriaceae - drug effects | Plasmids - genetics | Anti-Bacterial Agents - pharmacology | Drug Resistance, Multiple, Bacterial - genetics | Community-Acquired Infections - microbiology | Cross Infection - epidemiology | Enterobacteriaceae - classification | Usage | Enterobacter | Beta lactamases | Genetic aspects | Research | Antibacterial agents | Health aspects | Enterobacteriaceae | Life Sciences | Microbiology and Parasitology | Human health and pathology | Infectious diseases | Bacteriology | Class D OXA-48 Carbapenemase in Multidrug-Resistant Enterobacteria, Senegal | bacteria | enterobacteria | Senegal | Africa | letter | Letters to the Editor | Nosocomial infections | drug resistance | carbapenemase | OXA-48
INFECTIOUS DISEASES | BETA-LACTAMASE | TURKEY | PLASMID | IMMUNOLOGY | SPREAD | KLEBSIELLA-PNEUMONIAE | Senegal - epidemiology | Enterobacteriaceae - enzymology | Communicable Diseases, Emerging - microbiology | Community-Acquired Infections - epidemiology | Enterobacteriaceae Infections - microbiology | Humans | Bacterial Proteins - genetics | Enterobacteriaceae - genetics | Communicable Diseases, Emerging - epidemiology | Microbial Sensitivity Tests | Enterobacteriaceae Infections - epidemiology | beta-Lactamases - genetics | Cross Infection - microbiology | Enterobacteriaceae - drug effects | Plasmids - genetics | Anti-Bacterial Agents - pharmacology | Drug Resistance, Multiple, Bacterial - genetics | Community-Acquired Infections - microbiology | Cross Infection - epidemiology | Enterobacteriaceae - classification | Usage | Enterobacter | Beta lactamases | Genetic aspects | Research | Antibacterial agents | Health aspects | Enterobacteriaceae | Life Sciences | Microbiology and Parasitology | Human health and pathology | Infectious diseases | Bacteriology | Class D OXA-48 Carbapenemase in Multidrug-Resistant Enterobacteria, Senegal | bacteria | enterobacteria | Senegal | Africa | letter | Letters to the Editor | Nosocomial infections | drug resistance | carbapenemase | OXA-48
Journal Article