X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2435) 2435
Publication (540) 540
Book Chapter (112) 112
Patent (58) 58
Book Review (26) 26
Conference Proceeding (13) 13
Dissertation (12) 12
Data Set (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1357) 1357
humans (1327) 1327
animals (1316) 1316
immunology (1159) 1159
class-switch recombination (1156) 1156
class switch recombination (1081) 1081
mice (852) 852
somatic hypermutation (845) 845
b-lymphocytes - immunology (586) 586
biochemistry & molecular biology (439) 439
induced cytidine deaminase (426) 426
mutation (383) 383
article (380) 380
cytidine deaminase - metabolism (375) 375
cell biology (351) 351
b-cells (322) 322
cytidine deaminase - genetics (309) 309
immunoglobulins (306) 306
b-lymphocytes - metabolism (304) 304
dna repair (304) 304
b cells (301) 301
dna (297) 297
aid (296) 296
female (285) 285
research (265) 265
cytidine deaminase aid (260) 260
expression (239) 239
male (238) 238
molecular sequence data (229) 229
dna damage (227) 227
double-strand breaks (227) 227
single-stranded-dna (226) 226
immunoglobulin class switching (223) 223
vj recombination (221) 221
mice, knockout (216) 216
base sequence (215) 215
genetics & heredity (206) 206
mice, inbred c57bl (202) 202
activation (194) 194
multidisciplinary sciences (194) 194
genetic aspects (188) 188
proteins (187) 187
analysis (182) 182
activation-induced cytidine deaminase (173) 173
cells, cultured (171) 171
somatic hypermutation, immunoglobulin (170) 170
b-lymphocytes - cytology (168) 168
transcription (167) 167
genes (166) 166
cell line (163) 163
antibody diversification (161) 161
dna breaks, double-stranded (161) 161
genomic instability (161) 161
activation-induced deaminase (160) 160
immunoglobulin class switching - genetics (160) 160
cancer (158) 158
lymphocytes (155) 155
homologous recombination (153) 153
antibodies (152) 152
physiological aspects (152) 152
recombination, genetic (151) 151
medicine, research & experimental (148) 148
gene expression (147) 147
dna-binding proteins - genetics (146) 146
dna-binding proteins - metabolism (141) 141
oncology (139) 139
immunoglobulin genes (138) 138
immunoglobulin (137) 137
abridged index medicus (135) 135
t-cells (135) 135
immunoglobulin heavy chains - genetics (132) 132
flow cytometry (130) 130
lymphocytes b (130) 130
signal transduction (129) 129
hematology (127) 127
somatic hypermutation, immunoglobulin - genetics (127) 127
germinal center - immunology (125) 125
class switch (122) 122
nf-kappa-b (122) 122
transcription, genetic (122) 122
allergy (121) 121
cell differentiation (121) 121
immune system (120) 120
genes, immunoglobulin (119) 119
in-vivo (116) 116
adult (114) 114
amino acid sequence (113) 113
deoxyribonucleic acid--dna (113) 113
t-lymphocytes - immunology (112) 112
dna - metabolism (110) 110
hyper-igm syndrome (109) 109
enzymes (108) 108
dendritic cells (107) 107
mice, inbred balb c (107) 107
mice, transgenic (107) 107
antigens (106) 106
biology (106) 106
t cells (106) 106
differentiation (104) 104
recombination (104) 104
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2518) 2518
Chinese (59) 59
Japanese (14) 14
French (9) 9
German (6) 6
Dutch (1) 1
Portuguese (1) 1
Russian (1) 1
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Immunology, ISSN 1529-2908, 02/2012, Volume 13, Issue 2, pp. 170 - 180
Neutrophils use immunoglobulins to clear antigen, but their role in immunoglobulin production is unknown. Here we identified neutrophils around the marginal... 
ACTIVATION | CLASS SWITCH RECOMBINATION | SOMATIC HYPERMUTATION | COMMENSAL BACTERIA | MEMORY | INFLAMMATORY RESPONSES | RECEPTOR | DEGRADATION | IMMUNOLOGY | ANTIBODY-RESPONSES | APRIL | Spleen | Physiological aspects | Immunoglobulins | Research | Cytokines | Neutrophils
Journal Article
NATURE METHODS, ISSN 1548-7091, 12/2016, Volume 13, Issue 12, pp. 1029 - 1029
A large number of genetic variants have been associated with human diseases. However, the lack of a genetic diversification approach has impeded our ability to... 
CRISPR | SOMATIC HYPERMUTATION | ABL TYROSINE KINASE | STRUCTURAL BASIS | BCR-ABL | BIOCHEMICAL RESEARCH METHODS | URACIL-DNA GLYCOSYLASE | RESISTANCE | R-LOOPS | CLASS-SWITCH RECOMBINATION | MOLECULAR-MECHANISMS
Journal Article
European journal of immunology, ISSN 0014-2980, 2/2018, Volume 48, Issue 2, pp. 273 - 282
Activation-induced cytidine deminase (AID) is crucial for controlling the immunoglobulin (Ig) diversification processes of somatic hypermutation (SHM) and... 
YY1 | Somatic Hypermutation | AID | Class Switch Recombination
Journal Article
Cell Reports, ISSN 2211-1247, 08/2019, Volume 28, Issue 6, pp. 1387 - 1388
uncovered a critical role of 53BP1 in class switch recombination in B cells beyond its role in limiting end resection. 
CLASS SWITCH RECOMBINATION | RESECTION | DNA BREAKS | CELL BIOLOGY
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 07/2011, Volume 12, Issue 7, pp. 672 - U128
Mice deficient in sphingosine 1-phosphate receptor type 2 (S1P(2)) develop diffuse large B cell lymphoma. However, the role of S1P(2) in normal germinal center... 
MIGRATION | INHIBITION | PROTEIN-KINASE | ENDOTHELIAL-CELLS | SPHINGOSINE-1-PHOSPHATE | PTEN | CLASS-SWITCH RECOMBINATION | AKT | IMMUNOLOGY | LYMPHOCYTE EGRESS | TRANSLATIONAL CONTROL
Journal Article
11/2012
The processes of secondary antibody diversification are initiated by the mutagenic, B cell specific enzyme, Activation-Induced Deaminase (AID). AID deaminates... 
somatic hypermutation | 0982 | antibodies | class switch recombination | activation induced cytidine deaminase
Dissertation
Nature Reviews Immunology, ISSN 1474-1733, 03/2015, Volume 15, Issue 3, pp. 160 - 171
Journal Article
CURRENT OPINION IN IMMUNOLOGY, ISSN 0952-7915, 06/2013, Volume 25, Issue 3, pp. 366 - 372
Our bodies are continuously exposed to various types of infectious pathogens. Vaccinations are the most cost effective way to protect our bodies against a... 
B-CELLS | BCL6 | CLASS-SWITCH RECOMBINATION | DIFFERENTIATION | INDUCTION | IMMUNOLOGY | ICOS | TRANSCRIPTION FACTOR | EXPRESSION | IL-21 | CUTTING EDGE
Journal Article
Journal Article