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Journal Article
Brain structure & function, ISSN 1863-2653, 01/2019, Volume 224, Issue 3, pp. 1279 - 1290
BACE1 is a β-secretase involved in the cleavage of amyloid precursor protein and the pathogenesis of Alzheimer's disease (AD). The entorhinal cortex and the... 
b-Site APP cleaving enzyme 1 | Excitability | Oscillations | Amyloid precursor protein | Learning | Electrophysiological recording | Cortex (entorhinal) | Dentate gyrus | Plasticity (synaptic) | Clonal deletion | β-Amyloid | Paired-pulse inhibition | Alzheimer's disease | Secretase
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 06/2015, Volume 589, Issue 13, pp. 1418 - 1422
Journal Article
Alzheimer's Research and Therapy, ISSN 1758-9193, 12/2014, Volume 6, Issue 9, p. 89
beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the beta-secretase enzyme required for the production of the neurotoxic beta-amyloid (A beta)... 
CLOSE HOMOLOG | CLEAVING ENZYME-1 | BETA-SECRETASE ACTIVITY | OLFACTORY SENSORY NEURONS | INCREASED EXPRESSION | ASPARTYL PROTEASE | MEMORY DEFICITS | A-BETA | AMYLOID PRECURSOR PROTEIN | KNOCKOUT MICE | NEUROSCIENCES | CLINICAL NEUROLOGY | Advertising executives | Enzymes | Hydrolases | Drug targeting | Pharmaceutical industry | Alzheimer's disease | Amino acids
Journal Article
Journal Article
Journal Article
Journal of Neurotrauma, ISSN 0897-7151, 09/2012, Volume 29, Issue 13, pp. 2342 - 2351
Traumatic brain injury (TBI) leads to both acute injury and long-term neurodegeneration, and is a major risk factor for developing Alzheimer's disease (AD).... 
Original Articles | β-APP-cleaving enzyme-1 | traumatic brain injury | lithium | beta amyloid | learning and memory | PHOSPHORYLATION | ALZHEIMERS-DISEASE | NEUROTROPHIC FACTOR | GLYCOGEN-SYNTHASE KINASE-3 | INCREASES | CEREBROSPINAL-FLUID | NEUROSCIENCES | CLINICAL NEUROLOGY | INHIBITION | MOUSE MODEL | beta-APP-cleaving enzyme-1 | PRECURSOR PROTEIN | EXPRESSION | CRITICAL CARE MEDICINE | Neuroprotective Agents - therapeutic use | Amyloid Precursor Protein Secretases - genetics | Memory Disorders - physiopathology | Aspartic Acid Endopeptidases - biosynthesis | Brain Injuries - drug therapy | Nerve Degeneration - physiopathology | Memory Disorders - metabolism | Cognition Disorders - metabolism | Male | Aspartic Acid Endopeptidases - genetics | Brain Injuries - metabolism | Brain Injuries - physiopathology | Nerve Degeneration - metabolism | Amyloid beta-Peptides - metabolism | Disease Models, Animal | Cognition Disorders - physiopathology | Maze Learning - physiology | Aspartic Acid Endopeptidases - antagonists & inhibitors | Mice, Inbred C57BL | Treatment Outcome | Cognition Disorders - drug therapy | Maze Learning - drug effects | Gene Expression Regulation - drug effects | Amyloid beta-Peptides - antagonists & inhibitors | Animals | Memory Disorders - drug therapy | Lithium Compounds - therapeutic use | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Nerve Degeneration - drug therapy | Amyloid Precursor Protein Secretases - biosynthesis | Animal experimentation | Brain | Usage | Control | Amyloid beta-protein | Physiological aspects | Lithium | Research | Gene expression | Drug therapy | Health aspects | Injuries | Learning | Peptides | Neurodegeneration | Rodents | Animal memory | Brain damage | Original
Journal Article
by Jiang, CL and Zou, X and Zhu, RQ and Shi, YM and Wu, ZH and Zhao, F and Chen, L
JOURNAL OF NEUROSURGERY, ISSN 0022-3085, 07/2019, Volume 131, Issue 1, pp. 54 - 63
OBJECTIVE Intraventricular hemorrhage (IVH) is found in approximately 40% of intracerebral hemorrhages and is associated with increased mortality and poor... 
SURGERY | beta-site amyloid precursor protein cleaving enzyme-1 | c-Jun N-terminal kinase | ferritin | ACTIVATION | JNK | ALZHEIMERS-DISEASE | N-TERMINAL KINASE | HIPPOCAMPAL | IRON | T-MAZE | amyloid beta | vascular disorders | RAT MODEL | CLINICAL NEUROLOGY | BACE1 | intraventricular hemorrhage | neuroinflammation | MICROGLIA | INNATE IMMUNITY
Journal Article
Journal Article
Journal Article