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Nature, ISSN 0028-0836, 12/2010, Volume 468, Issue 7324, pp. 696 - 700
Parkinson's disease is a pervasive, ageing-related neurodegenerative disease the cardinal motor symptoms of which reflect the loss of a small group of neurons,... 
PATHOGENESIS | CELLS | SUBSTANTIA-NIGRA NEURONS | MULTIDISCIPLINARY SCIENCES | DYSFUNCTION | MUTATIONS | MITOCHONDRIAL-DNA DELETIONS | CALCIUM-CHANNEL BLOCKERS | PARKINSONS-DISEASE | Oncogene Proteins - genetics | Oxidative Stress | Calcium - metabolism | Iridoid Glycosides - pharmacology | Male | Neurons - cytology | Cyclophilins - metabolism | Calcium Channels, L-Type - pharmacology | Brain - metabolism | Iridoids | Mitochondrial Proteins - metabolism | Gene Deletion | Superoxides - metabolism | Neurons - metabolism | Parkinson Disease - metabolism | Calcium Signaling | Dopamine - metabolism | Brain - cytology | Parkinson Disease - pathology | Purines - pharmacology | Mitochondrial Proteins - antagonists & inhibitors | Oncogene Proteins - metabolism | Mice, Transgenic | Mitochondria - metabolism | Calcium Channel Blockers - pharmacology | Ion Channels - antagonists & inhibitors | Peroxiredoxins | Protein Deglycase DJ-1 | Parkinson Disease - prevention & control | Animals | Biological Clocks - physiology | Ion Channels - metabolism | Dihydropyridines - pharmacology | Oncogene Proteins - deficiency | Mice | Calcium Channels, L-Type - metabolism | Uncoupling Protein 1 | Development and progression | Calcium channels | Parkinson's disease | Dopaminergic mechanisms | Health aspects | Green fluorescent protein | Proteins | Neurotransmitters | Neurons | Parkinsons disease
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2015, Volume 22, Issue 6, pp. 1009 - 1019
The oncogene encodes MYC, a transcription factor that binds the genome through sites termed E-boxes (5′-CACGTG-3′), which are identical to the binding sites of... 
GENE | COPY NUMBER | TRANSCRIPTION | ENDOCRINOLOGY & METABOLISM | N-MYC | C-MYC | REV-ERB-ALPHA | NEUROBLASTOMA | OVARIAN-CANCER | DIFFERENTIATION | EXPRESSION | CELL BIOLOGY | Humans | CLOCK Proteins - chemistry | Glutamine - metabolism | CLOCK Proteins - genetics | RNA, Messenger - metabolism | Nuclear Receptor Subfamily 1, Group D, Member 1 - antagonists & inhibitors | Repressor Proteins - antagonists & inhibitors | CLOCK Proteins - metabolism | Period Circadian Proteins - genetics | RNA Interference | Base Sequence | Binding Sites | Dimerization | Nuclear Receptor Subfamily 1, Group D, Member 1 - metabolism | Genes, Reporter | Repressor Proteins - metabolism | Promoter Regions, Genetic | ARNTL Transcription Factors - genetics | Nuclear Receptor Subfamily 1, Group D, Member 1 - genetics | ARNTL Transcription Factors - metabolism | Repressor Proteins - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Circadian Rhythm | Proto-Oncogene Proteins c-myc - metabolism | Period Circadian Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | ARNTL Transcription Factors - chemistry | Cell Line, Tumor | Glucose - metabolism | Proto-Oncogene Proteins c-myc - genetics | RNA, Small Interfering - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Glucose metabolism | Medical colleges | Genomics | Cancer cells | Physiological aspects | Glucose | Dextrose | Cancer | Resveratrol
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 503, Issue 7476, pp. 414 - 417
Journal Article
Current Biology, ISSN 0960-9822, 01/2017, Volume 27, Issue 1, pp. 120 - 127
Journal Article
Nature, ISSN 0028-0836, 05/2012, Volume 485, Issue 7396, pp. 123 - 127
Journal Article
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 04/2016, Volume 18, Issue 4, pp. 355 - 365
Aim To determine the impact of a functional human islet clock on insulin secretion and gene transcription. Methods Efficient circadian clock disruption was... 
RNA sequencing | human pancreatic islet | circadian bioluminescence | insulin secretion | circadian clock | Circadian clock | Circadian bioluminescence | Human pancreatic islet | Insulin secretion | PERIPHERAL CLOCKS | SYSTEM | TRANSCRIPTOME | BEHAVIOR | BETA-CELLS | METABOLISM | CHANNEL | GENES | ENDOCRINOLOGY & METABOLISM | OSCILLATIONS | EXPRESSION | Islets of Langerhans - drug effects | Sodium-Potassium-Exchanging ATPase - genetics | Cation Transport Proteins - antagonists & inhibitors | Sodium-Potassium-Exchanging ATPase - chemistry | Zinc Transporter 8 | Humans | CLOCK Proteins - genetics | Gene Expression Profiling | Potassium Channels, Inwardly Rectifying - chemistry | Qa-SNARE Proteins - chemistry | CLOCK Proteins - metabolism | Insulin-Secreting Cells - metabolism | Vesicle-Associated Membrane Protein 3 - chemistry | GTP-Binding Protein alpha Subunits, Gq-G11 - chemistry | RNA Interference | Cation Transport Proteins - metabolism | Islets of Langerhans - metabolism | Islets of Langerhans - cytology | Qa-SNARE Proteins - genetics | Cation Transport Proteins - genetics | Potassium Channels, Inwardly Rectifying - antagonists & inhibitors | Insulin-Secreting Cells - cytology | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Insulin Secretion | Vesicle-Associated Membrane Protein 3 - antagonists & inhibitors | Vesicle-Associated Membrane Protein 3 - genetics | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Circadian Clocks - drug effects | Colforsin - pharmacology | Vesicle-Associated Membrane Protein 3 - metabolism | CLOCK Proteins - antagonists & inhibitors | Cells, Cultured | GTP-Binding Protein alpha Subunits, Gq-G11 - antagonists & inhibitors | Potassium Channels, Inwardly Rectifying - genetics | Gene Expression Regulation - drug effects | Hyperglycemia - metabolism | Sodium-Potassium-Exchanging ATPase - metabolism | Insulin - metabolism | Insulin-Secreting Cells - drug effects | Qa-SNARE Proteins - metabolism | Genes, Reporter - drug effects | Qa-SNARE Proteins - antagonists & inhibitors | RNA, Small Interfering | Cation Transport Proteins - chemistry | Potassium Channels, Inwardly Rectifying - metabolism | Pancreatic beta cells | RNA | Analysis | Glucose | Insulin | Dextrose | Circadian rhythm | Pancreas | Rodents | Circadian rhythms | Transcription | Secretion | Islet cells | siRNA | Islets of Langerhans | Gene expression
Journal Article
Cell Metabolism, ISSN 1550-4131, 10/2015, Volume 22, Issue 4, pp. 709 - 720
Journal Article
Science, ISSN 0036-8075, 2/2004, Volume 303, Issue 5660, pp. 1003 - 1006
Many plants flower in response to seasonal fluctuations in day length. The CONSTANS (CO) gene of Arabidopsis promotes flowering in long days. Flowering is... 
Messenger RNA | Plant growth regulators | Luminescence | Antibodies | Photoreceptors | Flowering | Reports | Gene expression regulation | Photoperiod | Plants | Circadian rhythm | CIRCADIAN CLOCK | ROLES | PHYTOCHROME-A | MULTIDISCIPLINARY SCIENCES | LIGHT | GENES | PLANTS | TIME | FLORAL INDUCTION | EXPRESSION | ARABIDOPSIS PHOTORECEPTORS | Darkness | Arabidopsis - physiology | Photosynthetic Reaction Center Complex Proteins - metabolism | Arabidopsis - growth & development | Ubiquitin - metabolism | Multienzyme Complexes - metabolism | Proteasome Endopeptidase Complex | RNA, Messenger - metabolism | RNA, Plant - metabolism | Recombinant Fusion Proteins - metabolism | Arabidopsis Proteins - metabolism | DNA-Binding Proteins - metabolism | Photoreceptor Cells | Cell Nucleus - metabolism | Cysteine Endopeptidases - metabolism | Photosynthetic Reaction Center Complex Proteins - genetics | Light | Phytochrome - metabolism | Plants, Genetically Modified | Gene Expression Regulation, Plant | Transcription, Genetic | Phytochrome - genetics | Drosophila Proteins | Arabidopsis Proteins - genetics | Flavoproteins - metabolism | Flavoproteins - genetics | Phytochrome B | RNA, Messenger - genetics | Receptors, G-Protein-Coupled | Phytochrome A | RNA, Plant - genetics | Transcription Factors - genetics | Circadian Rhythm | DNA-Binding Proteins - genetics | Flowers - growth & development | Arabidopsis - genetics | Transcription Factors - metabolism | Cryptochromes | Mutation | Eye Proteins | Photoreceptor Cells, Invertebrate | Plants, Flowering of | Genetic aspects | Proteins | Flowers & plants | Genes
Journal Article