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Journal Article
by Wang, M and Gan, DK and Huang, X and Xu, GZ
BMC OPHTHALMOLOGY, ISSN 1471-2415, 07/2016, Volume 16
Background: About 37 genes have been reported to be involved in autosomal recessive retinitis pigmentosa, a hereditary retinal disease. However, causative... 
Autosomal recessive retinitis pigmentosa | ALPHA-SUBUNIT | Targeted exome sequencing | GENES | CNGA1 | OPHTHALMOLOGY | DOMINANT | PERIPHERIN/RDS | PREVALENCE | CGMP-GATED CHANNEL | IDENTIFICATION
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 08/2011, Volume 15, Issue 8, pp. 1778 - 1787
In vertebrate rods, dark and light conditions produce changes in guanosine 3′,5′‐cyclic monophosphate (cGMP) and calcium (Ca 2+ ) levels, which are regulated... 
a mouse line carrying a missense mutation in | PDE, cGMP‐phosphodiesterase | gene therapy | H620Q | Pde6b | cGMP, guanosine 3′,5′‐cyclic monophosphate | CNGA1, cGMP‐gated cation channels | GNAT1, guanine nucleotide‐binding protein G(t) subunit alpha‐1 | (GUCY2e), (GUCY2f) guanylate cyclases 2e and 2f | ROS, rod outer segments | ERG, electroretinogram | shRNA, short hairpin RNA | lentivirus | Pde6b(H620Q), a mouse line carrying a missense mutation in Pde6b | CALCIUM-CHANNEL BLOCKER | EQUIVALENT-LIGHT HYPOTHESIS | MEDICINE, RESEARCH & EXPERIMENTAL | PDE, cGMP-phosphodiesterase | CNGA1, cGMP-gated cation channels | INHERITED RETINAL DEGENERATION | D-CIS-DILTIAZEM | MEDIATED GENE-TRANSFER | CELL BIOLOGY | RD MOUSE | IN-VIVO | GAMMA-SUBUNIT | LEBERS CONGENITAL AMAUROSIS | BETA-SUBUNIT | GNAT1, guanine nucleotide-binding protein G(t) subunit alpha-1 | cGMP, guanosine 3 ',5 '-cyclic monophosphate | Retina - metabolism | Calcium - metabolism | Humans | Molecular Sequence Data | Immunoblotting | Male | Cyclic Nucleotide Phosphodiesterases, Type 6 - genetics | Sodium - metabolism | RNA Interference | Base Sequence | Light | Female | Retinitis Pigmentosa - physiopathology | Cyclic Nucleotide-Gated Cation Channels - metabolism | Disease Models, Animal | Electroretinography | Retina - radiation effects | Cyclic Nucleotide Phosphodiesterases, Type 6 - metabolism | Cell Survival | Mice, Inbred C57BL | Retina - physiopathology | Cyclic Nucleotide-Gated Cation Channels - genetics | Receptors, Cell Surface - metabolism | Retinitis Pigmentosa - genetics | Retinitis Pigmentosa - metabolism | Guanylate Cyclase - metabolism | Mice, Knockout | Animals | Cyclic GMP - metabolism | Guanylate Cyclase - genetics | Mice | Photoreceptor Cells, Vertebrate - metabolism | Photoreceptor Cells, Vertebrate - pathology | Receptors, Cell Surface - genetics | Survival analysis | T cell receptors | Calcium | Sodium | Rodents | Index Medicus | Pde6bH620Q, a mouse line carrying a missense mutation in Pde6b | cGMP, guanosine 3′,5′-cyclic monophosphate
Journal Article
Channels, ISSN 1933-6950, 11/2014, Volume 8, Issue 6, pp. 528 - 535
A diffusion barrier segregates the plasma membrane of the rod photoreceptor outer segment into 2 domains; one which is optimized for the conductance of ions in... 
rhodopsin | morphogenesis | retina | cyclic nucleotide gated channel | photoreceptor | CNGA1 | CNGB1 | Morphogenesis | Rhodopsin | Photoreceptor | Cyclic nucleotide gated channel | Retina | GARP, glutamic acid-rich protein | PDE6, phosphodiesterase 6 | CNGA1, cyclic nucleotide gated channel α-1 | CNGB1, cyclic nucleotide gated channel β-1 | OS, outer segment | GC, guanylate cyclase | GPCR, G protein-coupled receptor | IS, inner segment | Dend2, Dendra2 | Rho, rhodopsin | GCAP, guanylate cyclase activating protein | guanylate cyclase activating protein | CYCLASE-ACTIVATING PROTEIN | outer segment | Dendra2 | TRANSPORT | CONE PHOTORECEPTORS | Dend2 | phosphodiesterase 6 | Rho | REGULATES TRAFFICKING | S-MODULIN | SUBUNIT | G protein-coupled receptor | PDE6 | RETINAL DEGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GCAP | glutamic acid-rich protein | cyclic nucleotide gated channel-1 | guanylate cyclase | GARP | GPCR | NUCLEOTIDE-GATED CHANNELS | inner segment | Xenopus | Amino Acid Sequence | Rod Cell Outer Segment - metabolism | Humans | Molecular Sequence Data | Protein Sorting Signals | Protein Subunits - metabolism | Protein Transport | Cyclic Nucleotide-Gated Cation Channels - chemistry | Animals | Cattle | Cyclic CMP - metabolism | Protein Binding | Binding Sites | Calcium Signaling | Cyclic Nucleotide-Gated Cation Channels - metabolism | Index Medicus
Journal Article
Journal Article
The Journal of Physiology, ISSN 0022-3751, 02/2015, Volume 593, Issue 4, pp. 857 - 870
Journal Article
Nature Communications, ISSN 2041-1723, 2012, Volume 3, Issue 1, pp. 973 - 973
Journal Article
Journal Article
Journal of General Physiology, ISSN 0022-1295, 08/2010, Volume 136, Issue 2, pp. 179 - 187
Journal Article