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Nature Structural and Molecular Biology, ISSN 1545-9993, 07/2013, Volume 20, Issue 7, pp. 827 - 835
The anaphase-promoting complex/cyclosome (APC/C) is a similar to 1.5-MDa multiprotein E3 ligase enzyme that regulates cell division by promoting timely... 
SPINDLE CHECKPOINT | ANAPHASE-PROMOTING COMPLEX | CYCLIN DEGRADATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | COACTIVATOR CDH1 | PROCESSIVITY FACTOR | CELL BIOLOGY | EMI1 | MITOTIC CHECKPOINT COMPLEX | D-BOX | UBIQUITIN CHAINS | BIOPHYSICS | APC/C INHIBITOR
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 11/2012, Volume 19, Issue 11, pp. 1116 - 1123
The anaphase-promoting complex/cyclosome (APC/C) bound to CDC20 (APC/C-CDC20) initiates anaphase by ubiquitylating B-type cyclins and securin. During... 
ANAPHASE-PROMOTING COMPLEX | PROTEIN | BUDDING YEAST | BIOCHEMISTRY & MOLECULAR BIOLOGY | BAC TRANSGENEOMICS | COACTIVATOR CDH1 | P31(COMET) | SPINDLE ASSEMBLY CHECKPOINT | MAD2 ACTIVATION | CELL BIOLOGY | UBIQUITINATION | BIOPHYSICS | BINDING
Journal Article
TRENDS IN CELL BIOLOGY, ISSN 0962-8924, 02/2019, Volume 29, Issue 2, pp. 117 - 134
The anaphase promoting corn plex/cyclosome (APC/C) E3 ligase controls mitosis and nonmitotic pathways through interactions with proteins that coordinate... 
CDC20 | ANAPHASE-PROMOTING COMPLEX | TPR SUBUNITS | SUBSTRATE-BINDING | LIGASE ACTIVITY | PROTEIN | MECHANISM | COACTIVATOR CDH1 | SPINDLE ASSEMBLY CHECKPOINT | CHAIN ELONGATION | CELL BIOLOGY
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2014, Volume 56, Issue 2, pp. 246 - 260
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2015, Volume 112, Issue 17, pp. 5272 - 5279
Journal Article
CELL DIVISION, ISSN 1747-1028, 12/2019, Volume 14, Issue 1, pp. 1 - 18
The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell... 
KEN-BOX | CHROMATID SEPARATION | DNA-DAMAGE | COACTIVATOR CDH1 | Substrate ordering | APC/C ACTIVATORS | Anaphase-promoting complex | CELL BIOLOGY | Ubiquitination | APC | Cell cycle | MITOTIC REGULATION | POLO-LIKE KINASE-1 | CELL-CYCLE | MOLECULAR-BASIS | DEPENDENT DEGRADATION | APC/C
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 04/2015, Volume 427, Issue 8, pp. 1748 - 1764
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2013, Volume 449, Issue 2, pp. 365 - 371
Mechanistic and structural studies of large multi-subunit assemblies are greatly facilitated by their reconstitution in heterologous recombinant systems. In... 
Anaphase-promoting complex/cyclosome (APC/C) | Recombinant expression | Ubiquitination | Single-particle electron microscopy | Three-dimensional structure | Cell cycle | MULTIPROTEIN EXPRESSION | cell cycle | BIOCHEMISTRY & MOLECULAR BIOLOGY | COACTIVATOR CDH1 | recombinant expression | DESTRUCTION BOX | single-particle electron microscopy | PROCESSIVITY FACTOR | 26S PROTEASOME | SUBSTRATE RECOGNITION | URACIL-EXCISION | MITOTIC CHECKPOINT COMPLEX | KEN BOX | ubiquitination | three-dimensional structure | PROTEIN COMPLEXES | anaphase-promoting complex/cyclosome (APC/C) | Anaphase-Promoting Complex-Cyclosome | Humans | Protein Multimerization | Substrate Specificity | Multiprotein Complexes - genetics | Ubiquitin-Protein Ligase Complexes - genetics | Protein Subunits - metabolism | Cell Cycle Proteins - chemistry | Multiprotein Complexes - metabolism | Protein Structure, Quaternary | Cell Cycle Proteins - genetics | Protein Subunits - genetics | Recombinant Proteins - metabolism | Cell Line | Recombinant Proteins - ultrastructure | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Microscopy, Electron | Ubiquitin-Protein Ligases - chemistry | Ubiquitin-Protein Ligase Complexes - chemistry | Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome | Multiprotein Complexes - chemistry | Animals | Ubiquitin-Protein Ligase Complexes - metabolism | Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome | Protein Subunits - chemistry | Ubiquitin-Protein Ligases - genetics
Journal Article
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 2017, Volume 313, Issue 1, pp. F30 - F46
Journal Article
Nature Cell Biology, ISSN 1465-7392, 06/2016, Volume 18, Issue 6, pp. 645 - 656
Journal Article
Molecular Cancer, ISSN 1476-4598, 03/2013, Volume 12, Issue 1, pp. 21 - 21
Journal Article
BMC Cancer, ISSN 1471-2407, 03/2015, Volume 15, Issue 1, p. 140