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BBA - Bioenergetics, ISSN 0005-2728, 1998, Volume 1364, Issue 2, pp. 222 - 235
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 06/2019, Volume 1867, Issue 6, pp. 604 - 615
In mammalian cells, human 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR), a rate-limiting endoplasmic reticulum (ER) bonded enzyme, plays a central... 
HepG2 cells | HMGCR | LDL-R | SRE | CRE | cholesterol accumulation | LUPIN PROTEIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RISK | COENZYME Q | CATALYTIC PORTION | SEE | BIOPHYSICS | STATIN THERAPY | SEED | NUTRITION | DYSLIPIDEMIA | EXPRESSION | Enzymes | Peptides | RNA | Low density lipoproteins | Physiological aspects | Homeostasis | Genetic transcription | Cells | Cholesterol
Journal Article
AGING-US, ISSN 1945-4589, 05/2019, Volume 11, Issue 9, pp. 2565 - 2565
Coenzyme Q(10) (CoQ(10)) is an endogenous lipophilic quinone, ubiquitous in biological membranes and endowed with antioxidant and bioenergetic properties, both... 
mitochondria | skin | Coenzyme Q | UBIQUINONE | DEFICIENCY | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | senescence | ANTIOXIDANT | ENDOTHELIAL-CELLS | BETA-GALACTOSIDASE | aging | STRESS | SIMVASTATIN | oxidative stress | AGE
Journal Article
2004, Methods in Enzymology, ISBN 0121827860, Volume 382, xxxviii, 572
Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers more clinical aspects of... 
Book
Pharmacological Research, ISSN 1043-6618, 09/2011, Volume 64, Issue 3, pp. 180 - 186
Statins, long known to be beneficial in conditions where dyslipidemia occurs by lowering serum cholesterol levels, also have been proposed for use in... 
Alzheimer disease | Pleiotropic functions | Statins | Statins as Janus molecules | OXIDATIVE STRESS | COA REDUCTASE INHIBITORS | CLINICAL-TRIAL COHORT | DRUG-INTERACTIONS | NITRIC-OXIDE SYNTHASE | MILD COGNITIVE IMPAIRMENT | CELL-DEATH | COENZYME Q | AMYLOID-BETA | PHARMACOLOGY & PHARMACY | AUTOIMMUNE-DISEASE | Fatty Acids, Monounsaturated - pharmacology | Lovastatin - pharmacology | Heptanoic Acids - therapeutic use | Humans | Heptanoic Acids - adverse effects | Neurodegenerative Diseases - drug therapy | Quinolines - pharmacology | Fluorobenzenes - pharmacology | Fatty Acids, Monounsaturated - therapeutic use | Fatty Acids, Monounsaturated - adverse effects | Pyrroles - adverse effects | Indoles - pharmacology | Pyrroles - therapeutic use | Heptanoic Acids - pharmacology | Lovastatin - therapeutic use | Lovastatin - adverse effects | Alzheimer Disease - drug therapy | Rosuvastatin Calcium | Pyrimidines - pharmacology | Cholesterol - metabolism | Sulfonamides - pharmacology | Atorvastatin Calcium | Pyrroles - pharmacology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Indoles - adverse effects | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Pyrimidines - adverse effects | Sulfonamides - adverse effects | Indoles - therapeutic use | Fluorobenzenes - adverse effects | Quinolines - therapeutic use | Fluorobenzenes - therapeutic use | Quinolines - adverse effects | Alzheimer's disease | Neuroprotection | Neurotoxicity | Neurodegenerative diseases | statins | Dyslipidemia | Clinical trials | Age | Cholesterol | Index Medicus
Journal Article