The New England Journal of Medicine, ISSN 0028-4793, 10/2011, Volume 365, Issue 16, pp. 1492 - 1501
In this study from South Africa, earlier initiation of antiretroviral therapy in patients with newly diagnosed HIV infection and TB was associated with higher...
SOUTH-AFRICA | MEDICINE, GENERAL & INTERNAL | HIV | INITIATION | EFAVIRENZ | DRUGS | Drug Administration Schedule | Humans | AIDS-Related Opportunistic Infections - drug therapy | Kaplan-Meier Estimate | Tuberculosis - complications | Male | CD4 Lymphocyte Count | Viral Load | Disease-Free Survival | Anti-Retroviral Agents - administration & dosage | Tuberculosis - drug therapy | HIV Infections - complications | Adult | Female | HIV Infections - drug therapy | HIV Infections - mortality | Antitubercular Agents - therapeutic use | Antiviral agents | Usage | Care and treatment | Patient outcomes | Comorbid patients | Tuberculosis | Antitubercular agents | Dosage and administration | Drug therapy, Combination | Diagnosis | Drug therapy | Health aspects | HIV infection | Bacilli | Cell survival | Immune reconstitution | Lymphocytes T | Inflammation | Patients | Immunosuppressive agents | Antiretroviral therapy | CD4 antigen | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Sputum | Death
SOUTH-AFRICA | MEDICINE, GENERAL & INTERNAL | HIV | INITIATION | EFAVIRENZ | DRUGS | Drug Administration Schedule | Humans | AIDS-Related Opportunistic Infections - drug therapy | Kaplan-Meier Estimate | Tuberculosis - complications | Male | CD4 Lymphocyte Count | Viral Load | Disease-Free Survival | Anti-Retroviral Agents - administration & dosage | Tuberculosis - drug therapy | HIV Infections - complications | Adult | Female | HIV Infections - drug therapy | HIV Infections - mortality | Antitubercular Agents - therapeutic use | Antiviral agents | Usage | Care and treatment | Patient outcomes | Comorbid patients | Tuberculosis | Antitubercular agents | Dosage and administration | Drug therapy, Combination | Diagnosis | Drug therapy | Health aspects | HIV infection | Bacilli | Cell survival | Immune reconstitution | Lymphocytes T | Inflammation | Patients | Immunosuppressive agents | Antiretroviral therapy | CD4 antigen | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Sputum | Death
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2011, Volume 365, Issue 6, pp. 493 - 505
In this large, international study of HIV-1–serodiscordant couples, the receipt of antiretroviral therapy by the infected partner decreased transmission to the...
MORTALITY | MEDICINE, GENERAL & INTERNAL | TRANSMISSION | COUNTRIES | INITIATION | MALAWI | IMMUNODEFICIENCY-VIRUS TYPE-1 | RETHINKING | HIV-1-INFECTED PATIENTS | COHORT | UGANDA | HIV-1 | HIV Infections - prevention & control | Anti-Retroviral Agents - therapeutic use | HIV Seropositivity | Humans | Anti-Retroviral Agents - adverse effects | Kaplan-Meier Estimate | Proportional Hazards Models | Male | Spouses | Treatment Outcome | Disease Progression | Disease Transmission, Infectious - prevention & control | Young Adult | Adolescent | Adult | Female | HIV Infections - drug therapy | HIV Infections - transmission | Sexual Partners | Drug Therapy, Combination | Antiviral agents | Usage | Patient outcomes | Management | Drug therapy | Health aspects | HIV infection | Public health | Fees & charges | Antiretroviral drugs | Couples | Enrollments | Laboratories | Hypersensitivity | Sexual transmission | Infections | Grants | Antiretroviral therapy | CD4 antigen | Disease prevention | Studies | Infectious diseases | Disease transmission | Tuberculosis | Human immunodeficiency virus--HIV | Counseling | Population
MORTALITY | MEDICINE, GENERAL & INTERNAL | TRANSMISSION | COUNTRIES | INITIATION | MALAWI | IMMUNODEFICIENCY-VIRUS TYPE-1 | RETHINKING | HIV-1-INFECTED PATIENTS | COHORT | UGANDA | HIV-1 | HIV Infections - prevention & control | Anti-Retroviral Agents - therapeutic use | HIV Seropositivity | Humans | Anti-Retroviral Agents - adverse effects | Kaplan-Meier Estimate | Proportional Hazards Models | Male | Spouses | Treatment Outcome | Disease Progression | Disease Transmission, Infectious - prevention & control | Young Adult | Adolescent | Adult | Female | HIV Infections - drug therapy | HIV Infections - transmission | Sexual Partners | Drug Therapy, Combination | Antiviral agents | Usage | Patient outcomes | Management | Drug therapy | Health aspects | HIV infection | Public health | Fees & charges | Antiretroviral drugs | Couples | Enrollments | Laboratories | Hypersensitivity | Sexual transmission | Infections | Grants | Antiretroviral therapy | CD4 antigen | Disease prevention | Studies | Infectious diseases | Disease transmission | Tuberculosis | Human immunodeficiency virus--HIV | Counseling | Population
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2008, Volume 359, Issue 21, pp. 2233 - 2244
The timing of initiation of antiretroviral therapy in HIV-infected infants has been debated, in part because of the potential long-term toxicity of the...
SURVIVAL | TRIAL | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | ZIDOVUDINE | HIV-1-INFECTED CHILDREN | COHORT | REGIMENS | DISEASE PROGRESSION | HIV-1 | Lamivudine - administration & dosage | Follow-Up Studies | Humans | Infant | Male | Zidovudine - administration & dosage | Anti-HIV Agents - administration & dosage | Lamivudine - adverse effects | Ritonavir - adverse effects | Treatment Failure | Female | HIV Infections - mortality | Drug Therapy, Combination | Drug Administration Schedule | Ritonavir - administration & dosage | Zidovudine - adverse effects | Anti-HIV Agents - adverse effects | Lopinavir | Pyrimidinones - adverse effects | CD4 Lymphocyte Count | Infectious Disease Transmission, Vertical | Disease Progression | HIV Infections - drug therapy | Pyrimidinones - administration & dosage | Antiviral agents | Control | Patient outcomes | Dosage and administration | HIV infection in children | Infants | Diagnosis | Antiretroviral drugs | Hospitals | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Mortality | Infections | Drug therapy | Age | Children & youth | Index Medicus | Abridged Index Medicus
SURVIVAL | TRIAL | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | ZIDOVUDINE | HIV-1-INFECTED CHILDREN | COHORT | REGIMENS | DISEASE PROGRESSION | HIV-1 | Lamivudine - administration & dosage | Follow-Up Studies | Humans | Infant | Male | Zidovudine - administration & dosage | Anti-HIV Agents - administration & dosage | Lamivudine - adverse effects | Ritonavir - adverse effects | Treatment Failure | Female | HIV Infections - mortality | Drug Therapy, Combination | Drug Administration Schedule | Ritonavir - administration & dosage | Zidovudine - adverse effects | Anti-HIV Agents - adverse effects | Lopinavir | Pyrimidinones - adverse effects | CD4 Lymphocyte Count | Infectious Disease Transmission, Vertical | Disease Progression | HIV Infections - drug therapy | Pyrimidinones - administration & dosage | Antiviral agents | Control | Patient outcomes | Dosage and administration | HIV infection in children | Infants | Diagnosis | Antiretroviral drugs | Hospitals | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Mortality | Infections | Drug therapy | Age | Children & youth | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 18, pp. 1726 - 1737
In this randomized, controlled trial in Africa and India, combination antiretroviral therapy was more effective than standard therapy in preventing...
PRETERM DELIVERY | CHILD-MORTALITY | MEDICINE, GENERAL & INTERNAL | TENOFOVIR DISOPROXIL FUMARATE | INFECTED WOMEN | PROGESTERONE LEVELS | ADVERSE BIRTH OUTCOMES | LOPINAVIR/RITONAVIR | LOPINAVIR EXPOSURE | PROTEASE | PREGNANCY | HIV Infections - prevention & control | Infant Mortality | Humans | African Americans | Perinatal Care | Infant | Young Adult | Adult | Female | HIV Infections - transmission | Drug Therapy, Combination | Infant, Newborn | Infant, Low Birth Weight | Anti-Retroviral Agents - therapeutic use | Tenofovir - therapeutic use | Zidovudine - adverse effects | Anti-Retroviral Agents - adverse effects | CD4 Lymphocyte Count | Gestational Age | Pregnancy | Infant, Premature | Zidovudine - therapeutic use | HIV Infections - ethnology | Nevirapine - administration & dosage | Infectious Disease Transmission, Vertical - prevention & control | Pregnancy Outcome | Prevention | Highly active antiretroviral therapy | Complications and side effects | Care and treatment | Nevirapine | Pregnant women | HIV patients | Dosage and administration | Research | HIV (Viruses) | Zidovudine | Health aspects | Emtricitabine | Neonates | Antiretroviral drugs | Breastfeeding & lactation | Ritonavir | Lopinavir | Lamivudine | Infants | Gestation | Antiretroviral therapy | Postpartum | CD4 antigen | Disease prevention | Tenofovir | Cost-benefit analysis | Disease transmission | Maternal & child health | Human immunodeficiency virus--HIV | Birth weight | Drug therapy
PRETERM DELIVERY | CHILD-MORTALITY | MEDICINE, GENERAL & INTERNAL | TENOFOVIR DISOPROXIL FUMARATE | INFECTED WOMEN | PROGESTERONE LEVELS | ADVERSE BIRTH OUTCOMES | LOPINAVIR/RITONAVIR | LOPINAVIR EXPOSURE | PROTEASE | PREGNANCY | HIV Infections - prevention & control | Infant Mortality | Humans | African Americans | Perinatal Care | Infant | Young Adult | Adult | Female | HIV Infections - transmission | Drug Therapy, Combination | Infant, Newborn | Infant, Low Birth Weight | Anti-Retroviral Agents - therapeutic use | Tenofovir - therapeutic use | Zidovudine - adverse effects | Anti-Retroviral Agents - adverse effects | CD4 Lymphocyte Count | Gestational Age | Pregnancy | Infant, Premature | Zidovudine - therapeutic use | HIV Infections - ethnology | Nevirapine - administration & dosage | Infectious Disease Transmission, Vertical - prevention & control | Pregnancy Outcome | Prevention | Highly active antiretroviral therapy | Complications and side effects | Care and treatment | Nevirapine | Pregnant women | HIV patients | Dosage and administration | Research | HIV (Viruses) | Zidovudine | Health aspects | Emtricitabine | Neonates | Antiretroviral drugs | Breastfeeding & lactation | Ritonavir | Lopinavir | Lamivudine | Infants | Gestation | Antiretroviral therapy | Postpartum | CD4 antigen | Disease prevention | Tenofovir | Cost-benefit analysis | Disease transmission | Maternal & child health | Human immunodeficiency virus--HIV | Birth weight | Drug therapy
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 6/2011, Volume 52, Issue 11, pp. 1374 - 1383
Background. The optimal time to initiate antiretroviral therapy (ART) in human immunodeficiency virus (HIV)—associated tuberculous meningitis is unknown....
Statistical median | HIV/AIDS | Antiretrovirals | Art therapy | Meningeal tuberculosis | HIV | Mortality | Random allocation | AIDS | Arts | HIV 1 | MORTALITY | SURVIVAL | THAILAND | INFECTIOUS DISEASES | HIV-INFECTION | ERA | ADOLESCENTS | CLINICAL-TRIALS | ADULTS | RISK | MICROBIOLOGY | IMMUNOLOGY | Lamivudine - administration & dosage | Humans | Antiretroviral Therapy, Highly Active - adverse effects | Male | Zidovudine - administration & dosage | Anti-HIV Agents - administration & dosage | Time Factors | Adult | Anti-Inflammatory Agents - administration & dosage | Female | HIV Infections - mortality | Antiretroviral Therapy, Highly Active - methods | Tuberculosis, Meningeal - mortality | Placebos - administration & dosage | Dexamethasone - administration & dosage | Tuberculosis, Meningeal - drug therapy | Benzoxazines - administration & dosage | Double-Blind Method | Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage | Anti-HIV Agents - adverse effects | Treatment Outcome | Tuberculosis, Meningeal - complications | HIV Infections - complications | Antitubercular Agents - administration & dosage | HIV Infections - drug therapy | Antiviral agents | Care and treatment | Patient outcomes | Dosage and administration | Drug therapy | Health aspects | HIV infection | Comorbid patients | Tuberculous meningitis
Statistical median | HIV/AIDS | Antiretrovirals | Art therapy | Meningeal tuberculosis | HIV | Mortality | Random allocation | AIDS | Arts | HIV 1 | MORTALITY | SURVIVAL | THAILAND | INFECTIOUS DISEASES | HIV-INFECTION | ERA | ADOLESCENTS | CLINICAL-TRIALS | ADULTS | RISK | MICROBIOLOGY | IMMUNOLOGY | Lamivudine - administration & dosage | Humans | Antiretroviral Therapy, Highly Active - adverse effects | Male | Zidovudine - administration & dosage | Anti-HIV Agents - administration & dosage | Time Factors | Adult | Anti-Inflammatory Agents - administration & dosage | Female | HIV Infections - mortality | Antiretroviral Therapy, Highly Active - methods | Tuberculosis, Meningeal - mortality | Placebos - administration & dosage | Dexamethasone - administration & dosage | Tuberculosis, Meningeal - drug therapy | Benzoxazines - administration & dosage | Double-Blind Method | Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage | Anti-HIV Agents - adverse effects | Treatment Outcome | Tuberculosis, Meningeal - complications | HIV Infections - complications | Antitubercular Agents - administration & dosage | HIV Infections - drug therapy | Antiviral agents | Care and treatment | Patient outcomes | Dosage and administration | Drug therapy | Health aspects | HIV infection | Comorbid patients | Tuberculous meningitis
Journal Article
Current Opinion in HIV and AIDS, ISSN 1746-630X, 07/2013, Volume 8, Issue 4, pp. 341 - 349
PURPOSE OF REVIEWTo review recent data about advances in ART. RECENT FINDINGSIn the last 2 years, clinical trials have demonstrated the safety and efficacy of...
darunavir/ritonavir | lopinavir/ritonavir | generic antiretrovirals | maraviroc | nevirapine | atazanavir | elvitegravir | raltegravir | nucleoside-sparing | dolutegravir | cobicistat | rilpivirine | INFECTIOUS DISEASES | COMBINATION THERAPY | CO-FORMULATED ELVITEGRAVIR | INITIAL TREATMENT | IMMUNOLOGY | RITONAVIR-BOOSTED ATAZANAVIR | EFAVIRENZ | DOUBLE-BLIND | HIV-1 INFECTION | INTEGRASE INHIBITOR | TREATMENT-NAIVE PATIENTS | HIV - enzymology | HIV Infections - drug therapy | Anti-Retroviral Agents - therapeutic use | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | HIV Integrase Inhibitors - therapeutic use | Index Medicus | AIDS/HIV
darunavir/ritonavir | lopinavir/ritonavir | generic antiretrovirals | maraviroc | nevirapine | atazanavir | elvitegravir | raltegravir | nucleoside-sparing | dolutegravir | cobicistat | rilpivirine | INFECTIOUS DISEASES | COMBINATION THERAPY | CO-FORMULATED ELVITEGRAVIR | INITIAL TREATMENT | IMMUNOLOGY | RITONAVIR-BOOSTED ATAZANAVIR | EFAVIRENZ | DOUBLE-BLIND | HIV-1 INFECTION | INTEGRASE INHIBITOR | TREATMENT-NAIVE PATIENTS | HIV - enzymology | HIV Infections - drug therapy | Anti-Retroviral Agents - therapeutic use | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | HIV Integrase Inhibitors - therapeutic use | Index Medicus | AIDS/HIV
Journal Article
JAMA, ISSN 0098-7484, 07/2004, Volume 292, Issue 2, pp. 224 - 236
CONTEXT Evidence suggests that since highly active antiretroviral therapy (HAART) became available, the prevalence of unprotected sex and the incidence of...
VIRAL LOAD | CONDOM USE | MEDICINE, GENERAL & INTERNAL | HIV-POSITIVE GAY | HETEROSEXUAL TRANSMISSION | TRANSMITTED DISEASES | VIROLOGICAL FAILURE | SAN-FRANCISCO | HOMOSEXUAL-MEN | COMBINATION THERAPIES | PROTEASE INHIBITORS | Antiretroviral Therapy, Highly Active | HIV Infections - prevention & control | Humans | Risk-Taking | Sexual Behavior - statistics & numerical data | HIV Infections - drug therapy | Health Knowledge, Attitudes, Practice | Viral Load | Drug therapy | Human immunodeficiency virus--HIV | Sexual behavior
VIRAL LOAD | CONDOM USE | MEDICINE, GENERAL & INTERNAL | HIV-POSITIVE GAY | HETEROSEXUAL TRANSMISSION | TRANSMITTED DISEASES | VIROLOGICAL FAILURE | SAN-FRANCISCO | HOMOSEXUAL-MEN | COMBINATION THERAPIES | PROTEASE INHIBITORS | Antiretroviral Therapy, Highly Active | HIV Infections - prevention & control | Humans | Risk-Taking | Sexual Behavior - statistics & numerical data | HIV Infections - drug therapy | Health Knowledge, Attitudes, Practice | Viral Load | Drug therapy | Human immunodeficiency virus--HIV | Sexual behavior
Journal Article