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Parasitology, ISSN 0031-1820, 9/2010, Volume 137, Issue 11, pp. 1621 - 1635
Journal Article
Drug Resistance Updates, ISSN 1368-7646, 2016, Volume 27, pp. 14 - 29
Abstract Multidrug resistance is a key determinant of cancer chemotherapy failure. One of the major causes of multidrug resistance is the enhanced efflux of... 
Infectious Disease | Hematology, Oncology and Palliative Medicine | P-glycoprotein | Novel drug target | Cancer chemotherapy | Nanoparticle | Multidrug resistance | ABC transporter | Next generation sequencing | P-GLYCOPROTEIN INHIBITOR | CYSTEINE-SCANNING MUTAGENESIS | CISPLATIN RESISTANCE | BREAST-CANCER | DELIVERY-SYSTEM | EXTRACELLULAR VESICLES | TRIHYDROCHLORIDE LY335979 | NUCLEOTIDE-BINDING SITES | IN-VIVO | PHARMACOLOGY & PHARMACY | MEMBRANE TOPOLOGY | Neoplasms - metabolism | RNA, Small Interfering - genetics | Drug Resistance, Multiple - genetics | Protein Structure, Secondary | Liposomes - administration & dosage | Drug Resistance, Multiple - drug effects | Humans | Small Molecule Libraries - therapeutic use | Models, Molecular | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Drug Resistance, Neoplasm - genetics | Neoplasms - therapy | ATP-Binding Cassette Transporters - genetics | Neoplasms - genetics | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Modulators - therapeutic use | Protein Domains | Combined Modality Therapy - methods | Nanoparticles - administration & dosage | Neoplasms - pathology | ATP-Binding Cassette Transporters - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects | RNA, Small Interfering - metabolism | Drugs | Proteins | Drug resistance in microorganisms | Chemotherapy | Analysis | Crystals | Structure | Health aspects | Protein binding | Cancer
Journal Article
Nutrients, ISSN 2072-6643, 08/2018, Volume 10, Issue 8, p. 970
Vitamin K is an essential nutrient involved in the regulation of blood clotting and tissue mineralization. Vitamin K oxidoreductase (VKORC1) converts vitamin K... 
VKORC1 | VKORC1L1 | Osteocalcin | Warfarin | GGCX | Vitamin K-dependent carboxylation | Coagulation | Vitamin K | Vitamin K oxidoreductase | DISULFIDE BOND FORMATION | EPOXIDE REDUCTASE | coagulation | vitamin K-dependent carboxylation | warfarin | GAMMA-GLUTAMYL CARBOXYLASE | NUTRITION & DIETETICS | COMBINED DEFICIENCY | BACTERIAL HOMOLOG | WARFARIN RESISTANCE | osteocalcin | EMBRYONIC LETHALITY | DEPENDENT CARBOXYLATION | MEMBRANE TOPOLOGY | ENERGY-METABOLISM | vitamin K oxidoreductase | Vitamin K 1 - analogs & derivatives | Liver - enzymology | Oxidation-Reduction | Humans | Structure-Activity Relationship | Vitamin K Epoxide Reductases - metabolism | Vitamin K 1 - metabolism | Warfarin - pharmacology | Gene Expression Regulation, Enzymologic | Vitamin K Epoxide Reductases - antagonists & inhibitors | Animals | Blood Coagulation - drug effects | Gene Expression Regulation, Developmental | Anticoagulants - pharmacology | Carboxylic Acids - metabolism | Protein Conformation | Protein Processing, Post-Translational | Evolution, Molecular | Vitamin K Epoxide Reductases - chemistry | Vitamin K Epoxide Reductases - genetics | Cell culture | Anticoagulants | Blood coagulation | Enzymes | Redundancy | Oxidoreductase | Liver | Quinone | Pharmacology | Clotting | Proteins | Vertebrates | Hemostasis | Mineralization | Carboxylation | Hemostatics | Reductase | Structure-function relationships
Journal Article
Journal Article