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Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 07/2015, Volume 100, pp. 34 - 43
Journal Article
British Journal of Cancer, ISSN 0007-0920, 04/2010, Volume 102, Issue 9, pp. 1355 - 1360
Journal Article
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 08/2016, Volume 16, Issue 8, pp. 942 - 960
an ethylene bridge. CA-4, inhibitor of polymerization of tubulin to microtubules, possesses a strong antitumor and anti-vascular properties both in vitro and... 
Synthesis; Biological activity | Combretastatin A-4 | Inhibitors of angiogenesis | CA-4 | Cancer therapy | DESIGN | CHEMISTRY, MEDICINAL | SERIES | ANTITUBULIN | ANTINEOPLASTIC AGENTS | Biological activity | DISCOVERY | POTENT | Synthesis | ONCOLOGY | 1,2,3-TRIAZOLE ANALOGS | INHIBITORS | BINDING
Journal Article
Journal Article
ONCOTARGET, ISSN 1949-2553, 11/2017, Volume 8, Issue 56, pp. 95648 - 95661
Solid tumours vary in sensitivity to the vascular disrupting agent combretastatin A-4 3-O-phosphate (CA4P... 
tumour microcirculation | BLOOD-VESSEL MATURATION | PROTEIN | PERMEABILITY | GROWTH FACTOR-A | adherens junctions | CANCER | SPHINGOSINE 1-PHOSPHATE | CELL BIOLOGY | CADHERIN | combretastatin | VE-cadherin | ENDOTHELIAL-CELLS | PHOSPHATE CA4P | sphingosine-1-phosphate | CARCINOMA
Journal Article
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 11/2017, Volume 203, pp. 193 - 199
Novel fluoro-analogs of potent vascular disrupting agents (VDAs), combretastains A-4 and A-1, were designed, synthesized and preliminary biological activity of select compounds examined... 
Structure-based drug design | In silico screening | Structure-activity relationship | Combretastatin A-4 and A-1 | Fluoro-analog | Anticancer agent | Vascular disrupting agent | ANTINEOPLASTIC AGENTS | CHEMISTRY, ORGANIC | CHEMISTRY, INORGANIC & NUCLEAR | In silica screening | PHOSPHATE | INHIBITOR | TUBULIN | Antimitotic agents | Analysis | Crystals | Polymerization | Drug discovery | Colchicine | Antineoplastic agents | Tubulins | Structure
Journal Article
Journal Article