Nature Reviews Microbiology, ISSN 1740-1526, 04/2013, Volume 11, Issue 4, pp. 227 - 238
Establishing and maintaining beneficial interactions between the host and its associated microbiota are key requirements for host health. Although the gut...
ADAPTIVE IMMUNITY | MUC2 MUCIN | OBESITY | T-CELL RESPONSES | LYMPHOID-TISSUES | ROR-GAMMA-T | COMMENSAL BACTERIA | INTESTINAL MICROBIOTA | COLORECTAL-CANCER | GERM-FREE MICE | MICROBIOLOGY | Immunity, Mucosal - immunology | Immune System - physiology | Signal Transduction | Health | Humans | Gastrointestinal Tract - microbiology | Homeostasis | Metagenome - physiology | Gastrointestinal Tract - growth & development | Host-Pathogen Interactions | Gastrointestinal Tract - immunology | Animals | Gastrointestinal Tract - physiology | Host-bacteria relationships | Physiological aspects | Research | Microbiota (Symbiotic organisms) | Basic Medicine | growth & development | Mucosal | Gastrointestinal Tract | microbiology | physiology | Immunity | Immune System | Medicinska grundvetenskaper | immunology | Metagenome
ADAPTIVE IMMUNITY | MUC2 MUCIN | OBESITY | T-CELL RESPONSES | LYMPHOID-TISSUES | ROR-GAMMA-T | COMMENSAL BACTERIA | INTESTINAL MICROBIOTA | COLORECTAL-CANCER | GERM-FREE MICE | MICROBIOLOGY | Immunity, Mucosal - immunology | Immune System - physiology | Signal Transduction | Health | Humans | Gastrointestinal Tract - microbiology | Homeostasis | Metagenome - physiology | Gastrointestinal Tract - growth & development | Host-Pathogen Interactions | Gastrointestinal Tract - immunology | Animals | Gastrointestinal Tract - physiology | Host-bacteria relationships | Physiological aspects | Research | Microbiota (Symbiotic organisms) | Basic Medicine | growth & development | Mucosal | Gastrointestinal Tract | microbiology | physiology | Immunity | Immune System | Medicinska grundvetenskaper | immunology | Metagenome
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 03/2014, Volume 15, Issue 3, pp. 317 - 328
Colorectal cancer (CRC) presents a considerable disease burden worldwide. The human colon is also an anatomical location with the largest number of microbes....
COMMENSAL BACTERIA | STREPTOCOCCUS-GALLOLYTICUS INFECTION | ESCHERICHIA-COLI | MICROBIOLOGY | ENTEROTOXIGENIC BACTEROIDES-FRAGILIS | BETA-GLUCURONIDASE INHIBITION | HUMAN GUT MICROBIOME | VIROLOGY | URSODEOXYCHOLIC ACID | COLORECTAL-CANCER | NF-KAPPA-B | TUMOR MICROENVIRONMENT | PARASITOLOGY | Gastrointestinal Tract - microbiology | Colorectal Neoplasms - microbiology | Colorectal Neoplasms - etiology | Microbiota | Carcinogenesis | Humans | Physiological aspects | Bacteria | Colon cancer | Xenobiotics | Public health
COMMENSAL BACTERIA | STREPTOCOCCUS-GALLOLYTICUS INFECTION | ESCHERICHIA-COLI | MICROBIOLOGY | ENTEROTOXIGENIC BACTEROIDES-FRAGILIS | BETA-GLUCURONIDASE INHIBITION | HUMAN GUT MICROBIOME | VIROLOGY | URSODEOXYCHOLIC ACID | COLORECTAL-CANCER | NF-KAPPA-B | TUMOR MICROENVIRONMENT | PARASITOLOGY | Gastrointestinal Tract - microbiology | Colorectal Neoplasms - microbiology | Colorectal Neoplasms - etiology | Microbiota | Carcinogenesis | Humans | Physiological aspects | Bacteria | Colon cancer | Xenobiotics | Public health
Journal Article
Immunity, ISSN 1074-7613, 04/2017, Volume 46, Issue 4, pp. 562 - 576
The microbiota plays a fundamental role in the induction, education, and function of the host immune system. In return, the host immune system has evolved...
COMMENSAL BACTERIA | ARYL-HYDROCARBON RECEPTOR | GERM-FREE-MICE | CHAIN FATTY-ACIDS | CD103(+)CD11B(+) DENDRITIC CELLS | REGULATORY T-CELLS | LECTIN REGIII-GAMMA | INNATE LYMPHOID-CELLS | GUT MICROBIOTA | IMMUNOLOGY | SEGMENTED FILAMENTOUS BACTERIA | Immunity, Innate - immunology | Microbiota - physiology | Models, Immunological | Animals | Microbiota - immunology | Immune System - microbiology | Immune Tolerance - immunology | Humans | Homeostasis - immunology | Immune System - immunology | Adaptive Immunity - immunology | Host-Pathogen Interactions - immunology | Microbiota (Symbiotic organisms) | Parasitic diseases | Antigens | Immunoglobulins | Adaptive systems | Peptides | Gram-positive bacteria | Infections | Feedback loops | Tissues | Immunity | Immunological tolerance | Inflammatory diseases | Immunology | Feedback | Bacteria | Skin | Immune system
COMMENSAL BACTERIA | ARYL-HYDROCARBON RECEPTOR | GERM-FREE-MICE | CHAIN FATTY-ACIDS | CD103(+)CD11B(+) DENDRITIC CELLS | REGULATORY T-CELLS | LECTIN REGIII-GAMMA | INNATE LYMPHOID-CELLS | GUT MICROBIOTA | IMMUNOLOGY | SEGMENTED FILAMENTOUS BACTERIA | Immunity, Innate - immunology | Microbiota - physiology | Models, Immunological | Animals | Microbiota - immunology | Immune System - microbiology | Immune Tolerance - immunology | Humans | Homeostasis - immunology | Immune System - immunology | Adaptive Immunity - immunology | Host-Pathogen Interactions - immunology | Microbiota (Symbiotic organisms) | Parasitic diseases | Antigens | Immunoglobulins | Adaptive systems | Peptides | Gram-positive bacteria | Infections | Feedback loops | Tissues | Immunity | Immunological tolerance | Inflammatory diseases | Immunology | Feedback | Bacteria | Skin | Immune system
Journal Article
Mucosal Immunology, ISSN 1933-0219, 07/2017, Volume 10, Issue 4, pp. 946 - 956
Intestinal IgA, which is regulated by gut microbiota, has a crucial role in maintenance of intestinal homeostasis and in protecting the intestines from...
CLASS SWITCH RECOMBINATION | IMMUNOGLOBULIN-A | GUT HOMEOSTASIS | COMMENSAL BACTERIA | DENDRITIC CELLS | INFLAMMATORY DISEASES | DIETARY FIBER | GENERATION | IMMUNOLOGY | RECEPTORS | T-CELLS | Butyrates - metabolism | Receptors, G-Protein-Coupled - metabolism | Dendritic Cells - immunology | Retinal Dehydrogenase - metabolism | Immunity, Mucosal | Acetates - chemistry | Fatty Acids, Volatile - metabolism | Intestines - immunology | Vitamin A - metabolism | Fatty Acids, Volatile - immunology | Tretinoin - metabolism | Butyrates - immunology | Female | Acetates - immunology | Immunoglobulin A - metabolism | Microbiota - immunology | Acetates - metabolism | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Animals | Butyrates - chemistry | Mice | Receptors, G-Protein-Coupled - genetics | Fatty Acids, Volatile - chemistry | Metabolites | Fatty acids | Rodents
CLASS SWITCH RECOMBINATION | IMMUNOGLOBULIN-A | GUT HOMEOSTASIS | COMMENSAL BACTERIA | DENDRITIC CELLS | INFLAMMATORY DISEASES | DIETARY FIBER | GENERATION | IMMUNOLOGY | RECEPTORS | T-CELLS | Butyrates - metabolism | Receptors, G-Protein-Coupled - metabolism | Dendritic Cells - immunology | Retinal Dehydrogenase - metabolism | Immunity, Mucosal | Acetates - chemistry | Fatty Acids, Volatile - metabolism | Intestines - immunology | Vitamin A - metabolism | Fatty Acids, Volatile - immunology | Tretinoin - metabolism | Butyrates - immunology | Female | Acetates - immunology | Immunoglobulin A - metabolism | Microbiota - immunology | Acetates - metabolism | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Animals | Butyrates - chemistry | Mice | Receptors, G-Protein-Coupled - genetics | Fatty Acids, Volatile - chemistry | Metabolites | Fatty acids | Rodents
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2017, Volume 474, Issue 11, pp. 1823 - 1836
The human gastrointestinal (GI) tract harbours a complex and dynamic population of microorganisms, the gut microbiota, which exert a marked influence on the...
EPITHELIAL BARRIER DYSFUNCTION | COLONIC MUCUS BARRIER | IMMUNE-SYSTEM | COMMENSAL BACTERIA | EARLY-LIFE | INTESTINAL MICROBIOTA | CHAIN FATTY-ACIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | AKKERMANSIA-MUCINIPHILA | BACTEROIDES-THETAIOTAOMICRON | SEGMENTED FILAMENTOUS BACTERIA | Symbiosis | Humans | Phylogeography - trends | Gastrointestinal Microbiome | Dysbiosis - microbiology | Evidence-Based Medicine | Dysbiosis - physiopathology | Dysbiosis - immunology | Animals | Phylogeography - methods | Host-Parasite Interactions | Dysbiosis - prevention & control | Health Status | gastrointestinal tract | Review | symbiosis | gut microbiota
EPITHELIAL BARRIER DYSFUNCTION | COLONIC MUCUS BARRIER | IMMUNE-SYSTEM | COMMENSAL BACTERIA | EARLY-LIFE | INTESTINAL MICROBIOTA | CHAIN FATTY-ACIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | AKKERMANSIA-MUCINIPHILA | BACTEROIDES-THETAIOTAOMICRON | SEGMENTED FILAMENTOUS BACTERIA | Symbiosis | Humans | Phylogeography - trends | Gastrointestinal Microbiome | Dysbiosis - microbiology | Evidence-Based Medicine | Dysbiosis - physiopathology | Dysbiosis - immunology | Animals | Phylogeography - methods | Host-Parasite Interactions | Dysbiosis - prevention & control | Health Status | gastrointestinal tract | Review | symbiosis | gut microbiota
Journal Article
世界胃肠病学杂志:英文版(电子版), ISSN 1007-9327, 2015, Volume 21, Issue 29, pp. 8787 - 8803
Relation between the gut microbiota and humanhealth is being increasingly recognised. It is nowwell established that a healthy gut flora is largelyresponsible...
microbiota | Immunomodulation | gut | function | Bioinformatics;Health | Metabolic | Normal | Normal gut microbiota | Health | Bioinformatics | Metabolic function | LACTIC-ACID | DENDRITIC CELLS | COMMENSAL BACTERIA | INTESTINAL MICROBIOTA | LINOLEIC-ACID | INNATE LYMPHOID-CELLS | SPATIAL-ORGANIZATION | MUCUS LAYERS | IMMUNE-SYSTEM | CHAIN FATTY-ACIDS | GASTROENTEROLOGY & HEPATOLOGY | Intestines - drug effects | Age Factors | Firmicutes - physiology | Humans | Computational Biology | Homeostasis | Firmicutes - genetics | Bacteroidetes - drug effects | Bacteroidetes - physiology | Synbiotics | Prebiotics | Host-Pathogen Interactions | Anti-Bacterial Agents - therapeutic use | Gastrointestinal Microbiome - drug effects | Intestines - microbiology | Diet | Bacteriological Techniques | Probiotics - therapeutic use | Firmicutes - drug effects | Health Status | Bacteroidetes - genetics | Review
microbiota | Immunomodulation | gut | function | Bioinformatics;Health | Metabolic | Normal | Normal gut microbiota | Health | Bioinformatics | Metabolic function | LACTIC-ACID | DENDRITIC CELLS | COMMENSAL BACTERIA | INTESTINAL MICROBIOTA | LINOLEIC-ACID | INNATE LYMPHOID-CELLS | SPATIAL-ORGANIZATION | MUCUS LAYERS | IMMUNE-SYSTEM | CHAIN FATTY-ACIDS | GASTROENTEROLOGY & HEPATOLOGY | Intestines - drug effects | Age Factors | Firmicutes - physiology | Humans | Computational Biology | Homeostasis | Firmicutes - genetics | Bacteroidetes - drug effects | Bacteroidetes - physiology | Synbiotics | Prebiotics | Host-Pathogen Interactions | Anti-Bacterial Agents - therapeutic use | Gastrointestinal Microbiome - drug effects | Intestines - microbiology | Diet | Bacteriological Techniques | Probiotics - therapeutic use | Firmicutes - drug effects | Health Status | Bacteroidetes - genetics | Review
Journal Article
Nature, ISSN 0028-0836, 01/2018, Volume 553, Issue 7689, pp. 427 - 436
The skin is a complex and dynamic ecosystem that is inhabited by bacteria, archaea, fungi and viruses. These microbes-collectively referred to as the skin...
MYCOBACTERIUM-TUBERCULOSIS | ATOPIC-DERMATITIS | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | PROPIONIBACTERIUM-ACNES | RESIDENT COMMENSAL BACTERIA | INNATE LYMPHOID-CELLS | LOW-OXYGEN TENSION | ANTIMICROBIAL PEPTIDES | RESISTANT STAPHYLOCOCCUS-AUREUS | STRATUM-CORNEUM LIPIDS | Symbiosis | Microbiota - physiology | Microbiota - immunology | Skin - microbiology | Health | Humans | Host-Pathogen Interactions - immunology | Skin - chemistry | Animals | Host-Pathogen Interactions - genetics | Microbial Interactions | Host-Pathogen Interactions - physiology | Skin - immunology | Pathogens | Immune response | Archaea | Homeostasis | Viruses | Inflammation | Mutualism | Immunity | Cell adhesion & migration | Pathogenicity | Fungi | Microbiota | Immunotherapy | Bacteria | Skin | Immune system
MYCOBACTERIUM-TUBERCULOSIS | ATOPIC-DERMATITIS | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | PROPIONIBACTERIUM-ACNES | RESIDENT COMMENSAL BACTERIA | INNATE LYMPHOID-CELLS | LOW-OXYGEN TENSION | ANTIMICROBIAL PEPTIDES | RESISTANT STAPHYLOCOCCUS-AUREUS | STRATUM-CORNEUM LIPIDS | Symbiosis | Microbiota - physiology | Microbiota - immunology | Skin - microbiology | Health | Humans | Host-Pathogen Interactions - immunology | Skin - chemistry | Animals | Host-Pathogen Interactions - genetics | Microbial Interactions | Host-Pathogen Interactions - physiology | Skin - immunology | Pathogens | Immune response | Archaea | Homeostasis | Viruses | Inflammation | Mutualism | Immunity | Cell adhesion & migration | Pathogenicity | Fungi | Microbiota | Immunotherapy | Bacteria | Skin | Immune system
Journal Article