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Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 718 - 728
Mouse conventional dendritic cells (cDCs) can be classified into two functionally distinct lineages: the CD8 alpha(+) (CD103(+)) cDC1 lineage, and the CD11b(+)... 
CLASSICAL DENDRITIC CELLS | HOMEOSTASIS | LYMPHOID-TISSUE | HEMATOPOIETIC STEM-CELLS | MOUSE | DYNAMICS | RECEPTOR | TRANSCRIPTION-FACTOR | IMMUNOLOGY | COMMITTED PROGENITORS | EXPRESSION | Antigens, CD - immunology | Stem Cells - immunology | Oligonucleotide Array Sequence Analysis | Dendritic Cells - immunology | Antigens, Ly - genetics | Transcriptome - immunology | Stem Cells - metabolism | Antigens, CD - metabolism | Lectins - metabolism | Flow Cytometry | Single-Cell Analysis - methods | Bone Marrow Cells - immunology | Integrin alpha Chains - immunology | Antigens, Ly - metabolism | Cell Lineage - genetics | Dendritic Cells - metabolism | Microscopy, Electron, Scanning | CD11b Antigen - immunology | Lectins - immunology | Mice, Inbred C57BL | Cells, Cultured | Receptors, Cell Surface - metabolism | Mice, Transgenic | Integrin alpha Chains - metabolism | Transcriptome - genetics | Receptors, Cell Surface - immunology | CD8 Antigens - immunology | CD8 Antigens - metabolism | Animals | Antigens, Ly - immunology | Dendritic Cells - ultrastructure | Lectins - genetics | CD11b Antigen - metabolism | Bone Marrow Cells - metabolism | Cell Lineage - immunology | Cluster Analysis | Receptors, Cell Surface - genetics | Medical research | Immune response | Dendritic cells | Cell development (Biology) | Bone marrow | Medicine, Experimental | Genetic aspects | Research | Properties | Index Medicus
Journal Article
Journal Article
Blood, ISSN 0006-4971, 05/2014, Volume 123, Issue 19, pp. 2968 - 2977
Runx1 and Cbf beta are critical for the establishment of definitive hematopoiesis and are implicated in leukemic transformation. Despite the absolute... 
LINEAGE COMMITMENT | STEM-CELLS | HUMAN BONE-MARROW | IN-VIVO | ACUTE MYELOID-LEUKEMIA | HEMATOLOGY | TRANSCRIPTION FACTOR | COMMITTED PROGENITORS | EXPRESSION | FETAL LIVER HEMATOPOIESIS | BINDING-FACTOR | Core Binding Factor Alpha 3 Subunit - metabolism | Interferon Regulatory Factors - metabolism | Anemia - pathology | Myeloproliferative Disorders - pathology | Core Binding Factor beta Subunit - genetics | Stem Cells - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Myeloproliferative Disorders - genetics | Cell Differentiation - genetics | Anemia - genetics | Flow Cytometry | Myeloproliferative Disorders - metabolism | Granulocytes - metabolism | Dendritic Cells - metabolism | Core Binding Factor beta Subunit - metabolism | Gene Expression | Core Binding Factor Alpha 2 Subunit - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interferon Regulatory Factors - genetics | Hematopoiesis - genetics | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | fms-Like Tyrosine Kinase 3 - metabolism | Mice, Knockout | Anemia - metabolism | Animals | Core Binding Factor Alpha 3 Subunit - genetics | Mice | Core Binding Factor Alpha 2 Subunit - genetics | Bone Marrow Cells - metabolism | Core Binding Factor Alpha 1 Subunit - genetics | Index Medicus | Abridged Index Medicus | Hematopoiesis and Stem Cells
Journal Article
Immunity, ISSN 1074-7613, 2006, Volume 24, Issue 6, pp. 801 - 812
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2006, Volume 103, Issue 3, pp. 672 - 677
Lymphoid lineage-committed progenitors, such as common lymphoid progenitors (CLPs), maintain a latent myeloid differentiation potential, which can be initiated... 
Myeloid cells | Transcription factors | B lymphocytes | Stromal cells | Genes | Stem cells | Cultured cells | Bone marrow cells | Down regulation | Progenitor cells | Lineage instruction | Commitment | Transcription factor | Cytokine receptor signaling | Hematopoiesis | TRANSCRIPTION FACTORS | transcription factor | COLONY-STIMULATING FACTOR | lineage instruction | MULTIDISCIPLINARY SCIENCES | cytokine receptor signaling | commitment | MOUSE BONE-MARROW | COMMITTED PROGENITORS | PU.1 | hematopoiesis | C/EBP-ALPHA | B-CELL | HEMATOPOIETIC STEM-CELLS | DIFFERENTIATION | CHAIN GENE | Myeloid Cells - cytology | Humans | Myeloid Cells - physiology | Stem Cells - cytology | Receptors, Interleukin-2 - genetics | Cell Differentiation - genetics | Interleukin-2 Receptor beta Subunit | Lymphocytes - physiology | CCAAT-Enhancer-Binding Protein-alpha - biosynthesis | PAX5 Transcription Factor - physiology | CCAAT-Enhancer-Binding Protein-alpha - physiology | PAX5 Transcription Factor - biosynthesis | Up-Regulation - physiology | Cell Differentiation - physiology | Cell Lineage - genetics | Receptors, Interleukin-2 - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Up-Regulation - genetics | Lymphocytes - cytology | Signal Transduction - genetics | Down-Regulation - genetics | Cell Lineage - physiology | Down-Regulation - physiology | Animals | Signal Transduction - physiology | Stem Cells - physiology | Mice | Receptors, Interleukin-2 - physiology | PAX5 Transcription Factor - antagonists & inhibitors | Proteins | Lymphatic system | Immunology | Cytokines | Binding sites | Index Medicus | Biological Sciences
Journal Article
INTERNATIONAL IMMUNOLOGY, ISSN 0953-8178, 10/2017, Volume 29, Issue 10, pp. 443 - 456
The basic helix-loop-helix transcription factor E2-2 is essential for the development of plasmacytoid dendritic cells (pDCs) but not conventional DCs (cDCs).... 
STEM-CELLS | COLONY-STIMULATING FACTOR | BONE-MARROW | RETINOIC-ACID | plasmacytoid dendritic cell | INTERFERON-PRODUCING CELLS | IMMUNOLOGY | FLT3 LIGAND | COMMITTED PROGENITORS | TRANSCRIPTION FACTOR E2-2 | E2-2 | DENDRITIC-CELL-DEVELOPMENT | common dendritic cell progenitors (CDP) | beta c cytokines | IN-VIVO
Journal Article
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 23, pp. 5757 - 5764
Lymphoid and myeloid lineage segregation is a major developmental step during early hematopoiesis from hematopoietic stem cells. It is not clear, however,... 
STEM-CELLS | B-LYMPHOCYTE | COMMITMENT | COLONY-STIMULATING FACTOR | BONE-MARROW | IN-VIVO | RECEPTORS | HEMATOLOGY | COMMITTED PROGENITORS | RAG1 LOCUS |