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1.
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Potassium-competitive acid blockers: Advanced therapeutic option for acid-related diseases
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 12/2016, Volume 168, pp. 12 - 22
Peptic ulcer | Gastric acid secretion | Potassium-competitive acid blocker | receptor | Acid-related diseases | Proton pump inhibitor | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Potassium - metabolism | Proton Pump Inhibitors - adverse effects | Proton Pump Inhibitors - pharmacology | Histamine H2 Antagonists - pharmacology | Gastroesophageal Reflux - physiopathology | Humans | Helicobacter Infections - complications | Gastric Acid - secretion | Gastrointestinal Agents - pharmacology | Animals | Helicobacter Infections - drug therapy | Drug Design | Peptic Ulcer - physiopathology | Gastrointestinal Agents - adverse effects | Helicobacter pylori - isolation & purification | Gastroesophageal Reflux - drug therapy | Peptic Ulcer - drug therapy | Gastroesophageal reflux | Care and treatment | Health aspects | Antacids | Index Medicus
Journal Article
Advances in therapy, ISSN 0741-238X, 7/2016, Volume 33, Issue 7, pp. 1140 - 1157
Potassium-competitive acid blockers | Vonoprazan | Acid-related diseases | TAK-438 | Rheumatology | Helicobacter pylori eradication | PPI | Internal Medicine | Oncology | Reflux esophagitis | Proton pump inhibitor | Medicine & Public Health | Gastroenterology | Cardiology | Pharmacology/Toxicology | Endocrinology | Lansoprazole | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Gastrointestinal Agents - pharmacology | Pyrroles - pharmacology | Pyrroles - pharmacokinetics | Sulfonamides - therapeutic use | Gastrointestinal Diseases - drug therapy | Humans | Gastrointestinal Agents - therapeutic use | Gastrointestinal Agents - pharmacokinetics | Pyrroles - therapeutic use | Sulfonamides - pharmacology | Sulfonamides - pharmacokinetics | Hydrogen-Ion Concentration | Gastroesophageal reflux | Physiological aspects | Peptic ulcer | Antacids | Genetic polymorphisms | Cytochrome P-450 | Health technology assessment
Journal Article
Molecular pharmacology, ISSN 0026-895X, 1998, Volume 53, Issue 2, pp. 195 - 201
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Binding, Competitive | Receptors, Neurotransmitter - antagonists & inhibitors | Humans | Xenopus laevis | Amino Acid Transport System X-AG | Structure-Activity Relationship | Oocytes | Excitatory Amino Acid Transporter 2 | Animals | Transfection | Cloning, Molecular | Excitatory Amino Acids - metabolism | Aspartic Acid - analogs & derivatives | Aspartic Acid - chemistry | Excitatory Amino Acid Antagonists - chemistry | COS Cells | Aspartic Acid - pharmacology | ATP-Binding Cassette Transporters - antagonists & inhibitors | Index Medicus
Journal Article
European journal of pharmaceutical sciences, ISSN 0928-0987, 03/2019, Volume 130, pp. 1 - 10
Journal Article
Digestion, ISSN 0012-2823, 03/2020, Volume 101, Issue 2, pp. 174 - 183
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 07/2017, Volume 25, Issue 14, pp. 3719 - 3735
Potassium-competitive acid blockers | H+,K+-ATPase | Docking analysis | 3,4-Dihydro-1H-spiro[naphthalene-2,2′-piperidin]-1-one derivatives | S-Enantiomer | Histamine - toxicity | Potassium - metabolism | Area Under Curve | Half-Life | Structure-Activity Relationship | Gastric Mucosa - metabolism | Gastric Acid - secretion | H(+)-K(+)-Exchanging ATPase - chemistry | Spiro Compounds - chemical synthesis | Gastric Mucosa - drug effects | Inhibitory Concentration 50 | Piperidines - pharmacokinetics | Proton Pump Inhibitors - chemical synthesis | Drug Evaluation, Preclinical | Binding Sites | Spiro Compounds - chemistry | Naphthalenes - chemistry | Piperidines - chemistry | H(+)-K(+)-Exchanging ATPase - metabolism | Rats | Piperidines - chemical synthesis | Spiro Compounds - pharmacokinetics | Potassium - chemistry | Administration, Intravenous | Animals | Proton Pump Inhibitors - chemistry | Proton Pump Inhibitors - pharmacokinetics | Gastric Mucosa - secretion | ROC Curve | Molecular Docking Simulation | Gastric Acid - metabolism | Antacids | Resveratrol | Gastroesophageal reflux | Dimethylformamide | Chemical tests and reagents | Lithium compounds | Cytokinins | Histamine | Proton pump inhibitors | Metallocenes | Derivatives (Financial instruments) | High performance liquid chromatography | Adenosine triphosphatase | Index Medicus
Journal Article
Journal of gastroenterology, ISSN 0944-1174, 6/2018, Volume 53, Issue 6, pp. 718 - 724
Potassium-competitive acid blocker | Medicine & Public Health | Helicobacter pylori | Colorectal Surgery | Hepatology | Gastroenterology | Abdominal Surgery | Children | Surgical Oncology | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Prevention | Urea | Antihistamines | Enzymes | Helicobacter infections | High schools | Junior high school students | Antibacterial agents | Antacids | Cancer | Confidence intervals | Urine | Clarithromycin | Vomiting | Hypersensitivity | Amoxicillin | Potassium | Stomach cancer | Gastric cancer | Enzyme-linked immunosorbent assay | Index Medicus
Journal Article
Digestive diseases and sciences, ISSN 0163-2116, 7/2016, Volume 61, Issue 7, pp. 1888 - 1894
Biochemistry, general | Potassium-competitive acid blocker | Vonoprazan | Medicine & Public Health | Rat | Hepatology | Gastric mucosa | Gastroesophageal reflux disease | TAK-438 | Gastroenterology | Oncology | Transplant Surgery | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Autoradiography | Animals | Proton Pump Inhibitors - pharmacokinetics | Pyrroles - pharmacokinetics | Rats | Male | Tritium | Gastric Mucosa - metabolism | Sulfonamides - pharmacokinetics | Gastroesophageal reflux | Antacids | Index Medicus | Abridged Index Medicus
Journal Article
Digestion, ISSN 0012-2823, 07/2017, Volume 95, Issue 4, pp. 281 - 287
Potassium-competitive acid blocker | Vonoprazan | Drug therapy | Proton pump inhibitor-refractory gastroesophageal reflux disease | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Humans | Middle Aged | Male | Proton Pump Inhibitors - therapeutic use | Gastroesophageal Reflux - complications | Sulfonamides - therapeutic use | Treatment Failure | Aged, 80 and over | Sleep Wake Disorders - prevention & control | Female | Aged | Gastroesophageal Reflux - drug therapy | Pyrroles - therapeutic use | Sleep Wake Disorders - etiology | Index Medicus
Journal Article
Journal of neurogastroenterology and motility, ISSN 2093-0879, 2018, Volume 24, Issue 3, pp. 334 - 344
Esophagitis | exchanging ATPase | Potassium-competitive acid blocker | Anti-inflammatory agents,non-steroidal | K | Helicobacter pylori | Gastroenterology & Hepatology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | non-steroidal | Review | H+, K+-exchanging ATPase | Anti-inflammatory agents
Journal Article
11.
Full Text
Pathogenesis of Potassium-Competitive Acid Blocker-Resistant Non-Erosive Reflux Disease
Digestion, ISSN 0012-2823, 10/2018, Volume 98, Issue 3, pp. 194 - 200
Non-erosive reflux disease | Vonoprazan | Impedance-pH monitoring | Helicobacter pylori | Potassium-competitive acid blocker-resistant | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Proton Pump Inhibitors - pharmacology | Gastroesophageal Reflux - diagnosis | Esophageal pH Monitoring | Gastroesophageal Reflux - pathology | Humans | Middle Aged | Heartburn - diagnosis | Male | Treatment Outcome | Proton Pump Inhibitors - therapeutic use | Gastroesophageal Reflux - complications | Heartburn - etiology | Gastric Acidity Determination | Female | Gastric Acid - metabolism | Gastroesophageal Reflux - drug therapy | Potassium | Drug Resistance | Heartburn - pathology | Index Medicus
Journal Article