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Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2011, Volume 187, Issue 1, pp. 172 - 180
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2012, Volume 189, Issue 8, pp. 3957 - 3969
The lectin pathway of complement is an important component of innate immunity. Its activation has been thought to occur via recognition of pathogens by... 
SYSTEM | INDIVIDUALS | PATTERN-RECOGNITION MOLECULES | COMPLEMENT FACTOR-D | MBL | 3MC SYNDROME | STOICHIOMETRY | MUTATIONS | IMMUNOLOGY | IDENTIFICATION | DEFICIENCY | Craniofacial Abnormalities - immunology | Transcriptional Activation - genetics | Complement Pathway, Mannose-Binding Lectin - immunology | Blepharoptosis - genetics | Eye Abnormalities - enzymology | Mannose-Binding Protein-Associated Serine Proteases - physiology | Eye Abnormalities - immunology | Humans | Heart Defects, Congenital - immunology | Craniosynostoses - enzymology | Blepharoptosis - immunology | Developmental Disabilities - genetics | Transcriptional Activation - immunology | Strabismus - genetics | Abdominal Muscles - abnormalities | Abnormalities, Multiple - immunology | Heart Defects, Congenital - genetics | Developmental Disabilities - enzymology | Blepharoptosis - enzymology | Heart Defects, Congenital - enzymology | Mannose-Binding Protein-Associated Serine Proteases - genetics | Complement Pathway, Alternative - genetics | Abnormalities, Multiple - genetics | Craniofacial Abnormalities - genetics | Strabismus - enzymology | Abdominal Muscles - immunology | Craniosynostoses - genetics | Complement Pathway, Mannose-Binding Lectin - genetics | Cryptorchidism - enzymology | Abdominal Muscles - enzymology | Hip Dislocation, Congenital - genetics | Codon, Nonsense | Eye Abnormalities - genetics | Animals | Craniofacial Abnormalities - enzymology | Craniosynostoses - immunology | Cryptorchidism - immunology | Hip Dislocation, Congenital - immunology | Complement Pathway, Alternative - immunology | Strabismus - immunology | Abnormalities, Multiple - enzymology | Developmental Disabilities - immunology | Hip Dislocation, Congenital - enzymology | Cryptorchidism - genetics
Journal Article
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2018, Volume 200, Issue 8, pp. 2786 - 2797
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 5/2019, Volume 39, Issue 5, pp. 794 - 807
We explored the involvement of the lectin pathway of complement in post-traumatic brain injury (TBI) pathophysiology in humans. Brain samples were obtained... 
MBL-associated serine proteases | Traumatic brain injury | neuroinflammation | complement system | lectin complement pathway | MANNOSE-BINDING LECTIN | FICOLIN-3 | INJURY | COMPONENTS | NEUROSCIENCES | INHIBITION | SERINE PROTEASE-3 | NEOANTIGEN | ENDOCRINOLOGY & METABOLISM | DYSFUNCTION | MONOCLONAL-ANTIBODIES | HEMATOLOGY | EXPRESSION | Original
Journal Article
PLOS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e110053
The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human... 
SYSTEM | IMMUNE | FATTY LIVER-DISEASE | INSULIN-RESISTANCE | DECAY-ACCELERATING FACTOR | MEMBRANE-ATTACK COMPLEX | NECROSIS-FACTOR-ALPHA | VASCULAR ENDOTHELIAL-CELLS | PROPERDIN | PROTECTS | MULTIDISCIPLINARY SCIENCES | Non-alcoholic Fatty Liver Disease - pathology | Complement C3-C5 Convertases - metabolism | Liver - pathology | Non-alcoholic Fatty Liver Disease - genetics | Complement C3 - metabolism | Humans | Liver - metabolism | Gene Expression Regulation | Non-alcoholic Fatty Liver Disease - metabolism | Complement Factor D | RNA, Messenger - biosynthesis | Inflammation - metabolism | Complement Factor H - metabolism | Complement Factor B - metabolism | Biopsy | Inflammation - genetics | Adult | Complement Pathway, Alternative - genetics | Inflammation - physiopathology | Properdin - metabolism | RNA | Obesity | Liver | Pathogenesis | Properdin | Homeostasis | Activation | Complement | Kinases | Alternative pathway | Western blotting | Proteins | Hepatitis | Cell activation | Complement factor H | Immunology | Rodents | Hepatology | Gastroenterology | Immune system | Liver diseases | Cytokines | Neutrophils | Leukocytes (neutrophilic) | Inflammation | Gene expression | Polymerase chain reaction | Complement activation | Hepatocytes | Surveillance | Decay-accelerating factor | Complement component C3 | Lectins | Insulin resistance | TNF inhibitors | Diabetes | Gastrointestinal surgery | Immunofluorescence
Journal Article
SEMINARS IN IMMUNOPATHOLOGY, ISSN 1863-2297, 01/2018, Volume 40, Issue 1, pp. 15 - 35
Journal Article
Seminars in Immunopathology, ISSN 1863-2297, 1/2018, Volume 40, Issue 1, pp. 15 - 35
This review is not intended to cover in detail all aspects of the discovery and evolution of our understanding of the “alternative pathway” of complement... 
Therapy | Biomedicine | Immunology | Amplification loop | Properdin | Internal Medicine | Regulation | Complement component C3b | Complement activation | Reviews | Alternative pathway | Complement component C3
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2016, Volume 7, p. 36
The complement system consists of effector proteins, regulators, and receptors that participate in host defense against pathogens. Activation of the complement... 
Systemic lupus erythematosus | Complement C2 | Complement C4 | Autoimmune diseases