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Thrombosis Research, ISSN 0049-3848, 1981, Volume 24, Issue 1, pp. 61 - 71
Journal Article
Biochemical Journal, ISSN 0264-6021, 1760, Volume 459, Issue 3, pp. 551 - 564
Hepatic glucose phosphorylation by GK (glucokinase) is regulated by GKRP (GK regulatory protein). GKRP forms a cytosolic complex with GK followed by nuclear... 
Allosteric regulation | Fructose phosphate ester | Glucokinase regulatory protein | Glucokinase | Metabolic regulation | Diabetes | Co-operativity | RAT-LIVER | GLYCEMIC CONTROL | ACTIVATION | fructose phosphate ester | BIOCHEMISTRY & MOLECULAR BIOLOGY | allosteric regulation | co-operativity | glucokinase regulatory protein | HEPATIC GLUCOKINASE | P446L VARIANT | FRUCTOSE | HUMAN GLUCOKINASE | STRUCTURAL BASIS | GLUCOSE | DIABETES THERAPY | diabetes | glucokinase | metabolic regulation | Adaptor Proteins, Signal Transducing - chemistry | Protein Unfolding | Allosteric Regulation | Humans | Protein Multimerization | Tryptophan - chemistry | Fructosephosphates - metabolism | Protein Interaction Domains and Motifs | Protein Stability | Glucokinase - chemistry | Recombinant Proteins - metabolism | Protein Refolding | Models, Molecular | Recombinant Proteins - chemistry | Spectrometry, Fluorescence | Glucokinase - genetics | Mutant Proteins - metabolism | Glucokinase - metabolism | Protein Transport | Mutant Proteins - chemistry | Adaptor Proteins, Signal Transducing - genetics | Glucose - metabolism | Ligands | Protein Conformation | Adaptor Proteins, Signal Transducing - metabolism | Amino Acid Substitution | T2D, Type 2 diabetes | WT, wild-type | rGKRP, rat GKRP | NPC, nuclear pore complex | PPI, protein–protein interaction | NATA, N-acetyl-L-tryptophanamide | xGKRP, Xenopus GKRP | MH, D-mannoheptulose | GKA, GK activator | hGK, human GK | F6P, fructose 6-phosphate | hGKRP, human GKRP | GCKR | xGK, Xenopus GK | GKRPI, GKRP inhibitor | GK, glucokinase | TF, tryptophan fluorescence | GCK | GKRP, GK regulatory protein | SIS, sugar isomerase | F1P, fructose 1-phosphate
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1782, Volume 289, Issue 21, pp. 14913 - 14924
Skeletal muscle atrophy is a common and debilitating condition that lacks an effective therapy. To address this problem, we used a systems-based discovery... 
HYPERTROPHY | ALPHA-TOMATINE | ACTIVATION | MANAGEMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | TOMATOES | SARCOPENIA | DEFICIENT MICE | EXPRESSION SIGNATURES | FAT MASS | PROTECTS | Gene Expression - drug effects | TOR Serine-Threonine Kinases - metabolism | Humans | Mitochondria, Muscle - metabolism | Drug Discovery - methods | Immunoblotting | Male | Multiprotein Complexes - genetics | Muscle, Skeletal - metabolism | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Tomatine - pharmacology | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Myoblasts, Skeletal - cytology | TOR Serine-Threonine Kinases - genetics | MCF-7 Cells | Muscle, Skeletal - drug effects | Muscle Proteins - metabolism | Muscular Atrophy - prevention & control | Mitochondria, Muscle - genetics | Myoblasts, Skeletal - metabolism | Cell Line | Muscular Atrophy - metabolism | Mice, Inbred C57BL | Cells, Cultured | Muscular Atrophy - genetics | Tomatine - analogs & derivatives | Reverse Transcriptase Polymerase Chain Reaction | Muscle Proteins - genetics | Animals | Signal Transduction - drug effects | Cell Line, Tumor | HL-60 Cells | Muscle Fibers, Skeletal - cytology | Mice | Mitochondria, Muscle - drug effects | Muscle, Skeletal - pathology | Myoblasts, Skeletal - drug effects | Skeletal Muscle | Skeletal Muscle Metabolism | Muscle Atrophy | Tomatidine | Metabolism | Systems Biology | mTOR complex (mTORC)
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1782, Volume 289, Issue 21, pp. 14881 - 14895
Journal Article
Tissue Antigens, ISSN 0001-2815, 07/2011, Volume 78, Issue 1, pp. 11 - 20
HLA‐B57 and HLA‐B58 are major histocompatibility class (MHC)‐I allotypes that are potentially predictive of important clinical immune phenotypes. HLA‐B*5701 is... 
peripheral blood mononuclear cells | mean fluorescence intensity | monoclonal antibody | human leukocyte antigen | drug hypersensitivity | Peripheral blood mononuclear cells | Monoclonal antibody | Drug hypersensitivity | Human leukocyte antigen | Mean fluorescence intensity | SPECIFICITY | HLA-B | DETERMINANT | ANTIBODY | IMMUNOLOGY | PATHOLOGY | CELL BIOLOGY | HLA-B-ASTERISK-5701 | INFECTION | ABACAVIR HYPERSENSITIVITY | Amino Acid Sequence | Antibody Specificity | Drug Hypersensitivity - prevention & control | Enzyme-Linked Immunosorbent Assay | Antibodies, Monoclonal - biosynthesis | Antibodies, Monoclonal - pharmacology | Humans | Cells, Cultured | HLA-B Antigens - immunology | Models, Molecular | Molecular Sequence Data | Antibodies, Monoclonal - isolation & purification | Mass Screening - methods | HLA-B Antigens - analysis | Animals | Time Factors | Drug Hypersensitivity - immunology | Drug Hypersensitivity - genetics | Antibody Formation | Mice | Mice, Inbred BALB C | Antibodies, Monoclonal - metabolism | HLA-B Antigens - genetics | Histocompatibility Testing - methods | Antigen-antibody reactions | Allergy | Care and treatment | Biological products | Gout | HLA histocompatibility antigens | Fluorescence | Blood banks | Allergic reaction | Antibacterial agents | Drug allergy | Prevention | Immunogenetics | Histocompatibility antigens | Monoclonal antibodies | Index Medicus | Flucloxacillin | Risk groups | Toxicity | Hypersensitivity | Liver | Clinical trials | Data processing | Allotypes | Immunosuppressive agents | Major histocompatibility complex | Acquired immune deficiency syndrome | Antibiotics | Abacavir | Histocompatibility antigen HLA | Tissue typing | allopurinol
Journal Article
by Wang, XQ and Gao, S and Cao, CS and Yu, LX and Guo, JF and Cao, XZ
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, ISSN 1088-4246, 05/1998, Volume 2, Issue 3, pp. 209 - 217
A stepwise synthesis method was used to encapsulate tetrachloro-tetramethyl porphyrin in NaCoX molecular sieve supercages. Characterization of the encapsulated... 
OXIDATION | molecular sieve supercages | PORPHYRINS | COMPLEXES | catalytic capability | ZEOLITES | synthesis methods | CHEMISTRY, MULTIDISCIPLINARY | metalloporphyrin | COBALT
Journal Article
Journal of the Association of Nurses in AIDS Care, ISSN 1055-3290, 1989
Journal
Developmental Medicine & Child Neurology, ISSN 0012-1622, 06/2011, Volume 53, Issue 6, pp. 565 - 568
Diagnosis of mitochondrial disease is often a challenge because of the extreme heterogeneity of the clinical phenotype and the variety of underlying gene... 
MANAGEMENT | COMPLEX-I-DEFICIENCY | LEIGH-SYNDROME | DISEASE | STROKE-LIKE-EPISODES | DISORDERS | PEDIATRICS | MELAS | DIAGNOSTIC-CRITERIA | DNA G13513A MUTATION | CLINICAL NEUROLOGY | CHILDREN | Humans | Family Health | Male | Mutation - genetics | MELAS Syndrome - genetics | Magnetic Resonance Imaging | Phenotype | DNA, Mitochondrial - genetics | MELAS Syndrome - pathology | Adult | Female | Child | Infant, Newborn
Journal Article
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, ISSN 1553-3174, 05/2011, Volume 41, Issue 5, pp. 413 - 424
Reactive oxygen species (ROS), such as superoxide anion and hydroxyl radicals, can attack cellular biomolecules, such as DNA, lipids, and proteins, to cause... 
reductive activity | free radicals | pyridoxine | transition metal ions | pyridoxine-metal complexes | mass spectra | antioxidant activity | IRON(III) | COPPER(II) | COBALT(II) | NANOSCIENCE & NANOTECHNOLOGY | ZINC(II) | CHEMISTRY, INORGANIC & NUCLEAR | SCHIFF-BASE | VITAMIN | Antioxidants | Transition metals | Synthesis | Hydroxyl radicals | Biomolecules | Nanostructure | Palladium | Pyridoxine
Journal Article
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, ISSN 1553-3174, 05/2011, Volume 41, Issue 5, pp. 484 - 490
This article presents the synthesis of new Schiff base ligand and preparation of its transition metal complexes with copper (II), nickel (II), zinc (II), and... 
bimetallic complex | Schiff base | tetradentate ligand | bissalophen | CRYSTAL-STRUCTURE | COPPER(II) | CU(II) | ZN(II) | COBALT(II) | NANOSCIENCE & NANOTECHNOLOGY | NICKEL(II) | NI(II) | ZINC(II) COMPLEXES | CHEMISTRY, INORGANIC & NUCLEAR | FLUORESCENCE | METAL-COMPLEXES | Schiff bases | Spectroscopy | Synthesis | Ethyl alcohol | Fluorescence | Ligands | Nanostructure | Zinc
Journal Article