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index medicus (214) 214
biochemistry & molecular biology (160) 160
humans (155) 155
nadph oxidase (149) 149
respiratory burst oxidase (141) 141
chronic granulomatous-disease (102) 102
nadph oxidases - metabolism (101) 101
animals (96) 96
phosphorylation (91) 91
activation (85) 85
cell-free system (81) 81
phosphoproteins - metabolism (67) 67
components (66) 66
cell biology (58) 58
immunology (57) 57
p47 (53) 53
respiratory burst (52) 52
human-neutrophils (51) 51
superoxide (50) 50
component p47 (48) 48
plasma-membrane (48) 48
neutrophils - metabolism (47) 47
protein-kinase-c (45) 45
superoxides - metabolism (41) 41
nadph oxidases - genetics (40) 40
cytosolic component (39) 39
hematology (39) 39
superoxide production (39) 39
enzyme activation (38) 38
reactive oxygen species - metabolism (38) 38
translocation (38) 38
nadph oxidases (36) 36
neutrophils (36) 36
p67 (36) 36
oxidases (35) 35
biophysics (34) 34
molecular sequence data (34) 34
amino acid sequence (33) 33
reactive oxygen species (33) 33
cells, cultured (32) 32
component (32) 32
cytosolic components (32) 32
mice (32) 32
neutrophils - enzymology (32) 32
phosphoproteins - genetics (32) 32
nadh oxidase (30) 30
proteins (30) 30
src homology-3 domains (30) 30
expression (26) 26
sh3 domain (26) 26
gtp-binding protein (25) 25
complex (24) 24
neutrophils - drug effects (24) 24
phagocyte nadph oxidase (24) 24
neutrophil (23) 23
human neutrophils (22) 22
nadph oxidases - chemistry (22) 22
oxidative stress (22) 22
protein kinase c - metabolism (22) 22
signal transduction (22) 22
flavocytochrome b (21) 21
male (20) 20
n-formylmethionine leucyl-phenylalanine - pharmacology (19) 19
phosphoproteins - chemistry (19) 19
protein (19) 19
components p47 (18) 18
enzyme inhibitors - pharmacology (18) 18
multidisciplinary sciences (18) 18
recombinant proteins - metabolism (18) 18
binding (17) 17
cells (17) 17
endocrinology & metabolism (17) 17
nadph oxidase components (17) 17
p67-phox (17) 17
phagocytes (17) 17
research (17) 17
tetradecanoylphorbol acetate - pharmacology (17) 17
macrophages (16) 16
medicine, research & experimental (16) 16
nadph oxidase 2 (16) 16
protein binding (16) 16
cell membrane - metabolism (15) 15
cytochrome-b (15) 15
dose-response relationship, drug (15) 15
enzyme activation - drug effects (15) 15
female (15) 15
membrane (15) 15
mutation (15) 15
oxidase component p47 (15) 15
rats (15) 15
sodium dodecyl-sulfate (15) 15
angiotensin-ii (14) 14
binding sites (14) 14
chronic granulomatous disease (14) 14
cytochrome b (14) 14
cytosol - metabolism (14) 14
nadph oxidases - antagonists & inhibitors (14) 14
neutrophil nadph oxidase (14) 14
peripheral vascular disease (14) 14
abridged index medicus (13) 13
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JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 07/2006, Volume 116, Issue 7, pp. 2033 - 2043
Neutrophil NADPH oxidase plays a key role in host defense and in inflammation by releasing large amounts of superoxide and other ROSs. Proinflammatory... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPIRATORY BURST OXIDASE | TUMOR-NECROSIS-FACTOR | SIGNALING PATHWAYS | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | FORMYL-PEPTIDES | TNF-ALPHA | PLASMA-MEMBRANE | COMPONENT P47(PHOX) | FACTOR-ALPHA
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 07/2003, Volume 278, Issue 27, pp. 25234 - 25246
The catalytic core of a superoxide-producing NADPH oxidase (Nox) in phagocytes is gp91(phox)/Nox2, a membrane-integrated protein that forms a heterodimer with... 
RESPIRATORY BURST OXIDASE | PROTEIN-KINASE-C | NAD(P)H OXIDASE | IN-VITRO | CHRONIC GRANULOMATOUS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FLAVOCYTOCHROME B | CYTOCHROME B | SMOOTH-MUSCLE CELLS | SH3 DOMAIN | COMPONENTS P47(PHOX)
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 11/2004, Volume 173, Issue 9, pp. 5730 - 5738
Our laboratory is interested in understanding the regulation of NADPH oxidase activity in human monocyte/macrophages. Protein kinase C (PKC) is reported to be... 
OXIDATION | RESPIRATORY BURST OXIDASE | CYTOSOLIC PHOSPHOLIPASE A | NADPH-OXIDASE | HUMAN-NEUTROPHILS | LOW-DENSITY-LIPOPROTEIN | SITES | IMMUNOLOGY | SUPEROXIDE ANION PRODUCTION | PLASMA-MEMBRANE | COMPONENT P47(PHOX)
Journal Article
by Li, JM and Shah, AM
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 04/2003, Volume 278, Issue 14, pp. 12094 - 12100
Endothelial cells express a constitutively active phagocyte-type NADPH oxidase whose activity is augmented by agonists such as angiotensin II. We recently... 
HYPERTROPHY | NAD(P)H OXIDASE | OXIDATIVE STRESS | CYTOSOLIC COMPONENT | PHOSPHORYLATION | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICE | SUPEROXIDE PRODUCTION | RENAL DISEASES | SMOOTH-MUSCLE CELLS
Journal Article
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, ISSN 1079-5642, 02/2019, Volume 39, Issue 2, pp. 224 - 236
Objective- PDI (protein disulfide isomerase A1) was reported to support Nox1 (NADPH oxidase) activation mediated by growth factors in vascular smooth muscle... 
MIGRATION | SUPEROXIDE | NADPH oxidases | PHOSPHORYLATION | protein disulfide isomerase | cysteine | IDENTIFICATION | RESPIRATORY BURST OXIDASE | SUBUNIT P47(PHOX) | NAD(P)H OXIDASE | vascular diseases | mass spectrometry | PERIPHERAL VASCULAR DISEASE | COMPONENT | HEMATOLOGY | ASSOCIATION | EXPRESSION
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 05/2003, Volume 170, Issue 10, pp. 5302 - 5308
Respiratory burst activity and phosphorylation of an NADPH oxidase component, p47(phox), during neutrophil stimulation are mediated by phosphatidylinositol... 
SUBUNIT P47(PHOX) | ACTIVATED PROTEIN-KINASE | LEUKOCYTE NADPH OXIDASE | P38 | PHOSPHATIDYLINOSITOL 3-KINASE | TNF-ALPHA | IMMUNOLOGY | PHORBOL ESTER | SIGNAL-REGULATED KINASE | PHOSPHOINOSITIDE 3-KINASE-GAMMA | COMPONENT P47(PHOX)
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 06/2002, Volume 41, Issue 24, pp. 7743 - 7750
Production of superoxide anions by the multicomponent enzyme of human neutrophil NADPH oxidase is accompanied by extensive phosphorylation of p47(phox), one of... 
RESPIRATORY BURST OXIDASE | TRANSLOCATION | PROTEIN-KINASE-C | COMPLEX | HUMAN NEUTROPHILS | CYTOSOLIC COMPONENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUPEROXIDE PRODUCTION | PHORBOL ESTER | COMPONENT P47(PHOX) | SUBUNIT
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 05/2003, Volume 278, Issue 22, pp. 20006 - 20012
Superoxide production by phagocytes involves activation of a multi-component NADPH oxidase. Recently, several homologues of the catalytic component of the... 
ACTIVATION DOMAIN | TRANSFORMATION | RESPIRATORY BURST OXIDASE | PHOSPHORYLATION | CLONING | CHRONIC GRANULOMATOUS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FLAVOCYTOCHROME B | COMPONENTS | PHAGOCYTE NADPH OXIDASE | IDENTIFICATION
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2003, Volume 100, Issue 9, pp. 5130 - 5135
The leukocyte NADPH oxidase catalyzes the reduction of oxygen to O-2(-) at the expense of NADPH. Extensive phosphorylation of the oxidase subunit p47(PHOX)... 
RESPIRATORY BURST OXIDASE | TRANSLOCATION | PROTEIN-KINASE-B | NEUTROPHIL ACTIVATION | 3-KINASE | MEMBRANE | MULTIDISCIPLINARY SCIENCES | COMPONENT | SUBUNIT
Journal Article
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 10/2003, Volume 171, Issue 8, pp. 4392 - 4398
Phosphorylation of p47(phox) is a key event in NADPH oxidase activation. We examined the ability of proinflammatory cytokines such as TNFalpha, IL-1, and G-CSF... 
RESPIRATORY BURST OXIDASE | NADPH OXIDASE | TRANSLOCATION | TUMOR-NECROSIS-FACTOR | ACTIVATED PROTEIN-KINASE | TYROSINE PHOSPHORYLATION | GM-CSF | FORMYL-PEPTIDES | SITES | IMMUNOLOGY | COMPONENT P47(PHOX)
Journal Article
by Fan, LM and Teng, L and Li, JM
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, ISSN 1079-5642, 10/2009, Volume 29, Issue 10, pp. 1651 - U609
Objective-p40(phox) is an important regulatory subunit of NADPH oxidase, but its role in endothelial reactive oxygen species (ROS) production remains unknown.... 
endothelial cells | PROTEIN | SUPEROXIDE-PRODUCTION | PHOSPHORYLATION | KINASE | NECROSIS-FACTOR-ALPHA | ANGIOTENSIN-II | NADPH OXIDASE ACTIVATION | HBP1 TRANSCRIPTIONAL REPRESSOR | CYTOSOLIC COMPONENT | gene regulation | NADPH oxidase | reactive oxygen species | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2000, Volume 165, Issue 9, pp. 5238 - 5244
Phosphorylation of p47 phagocyte oxidase, (p47(phox)), one of the NADPH oxidase components, is essential for the activation of this enzyme and for superoxide... 
RESPIRATORY BURST OXIDASE | NADPH OXIDASE | SUBUNIT P47(PHOX) | CONFORMATIONAL-CHANGES | COLONY-STIMULATING FACTOR | GM-CSF | IN-VIVO | SUPEROXIDE PRODUCTION | TNF-ALPHA | IMMUNOLOGY | COMPONENT P47(PHOX)
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 04/2009, Volume 419, pp. 329 - 338
Journal Article
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