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Lancet Neurology, ISSN 1474-4422, 2010, Volume 9, Issue 4, pp. 363 - 372
Background Carbon-11-labelled Pittsburgh compound B (C-11-PiB) PET is a marker of cortical fibrillar amyloid-beta load in vivo. We used C-11-PiB PET to... 
IMMUNIZATION | PROTEIN | CLINICAL-TRIALS | FOLLOW-UP | PATHOLOGY | CEREBROSPINAL-FLUID | RATING-SCALE | BINDING | PITTSBURGH COMPOUND-B | BRAIN | CLINICAL NEUROLOGY
Journal Article
LANCET NEUROLOGY, ISSN 1474-4422, 02/2008, Volume 7, Issue 2, pp. 129 - 135
Background Amyloid-beta (AP) plaque formation is a hallmark of Alzheimer's disease (AD) and precedes the onset of dementia. A beta imaging should allow earlier... 
C-11-PIB PET | DIAGNOSIS | POSITRON-EMISSION-TOMOGRAPHY | DEMENTIA | DEPOSITION | COGNITIVE IMPAIRMENT | PLAQUES | PREVALENCE | PITTSBURGH COMPOUND-B | BRAIN | CLINICAL NEUROLOGY
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 02/2016, Volume 57, Issue 2, pp. 208 - 214
Imaging of neurofibrillary pathology in the brain helps in diagnosing dementia, tracking disease progression, and evaluating the therapeutic efficacy of... 
DEMENTIA | tau | C-11-PIB | PLAQUES | FUTURE | PITTSBURGH COMPOUND-B | BETA | POSITRON-EMISSION-TOMOGRAPHY | radiotracer | F-18-THK5351 | TANGLES | Alzheimer's disease | DERIVATIVES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | PHF-TAU RADIOLIGAND
Journal Article
LANCET NEUROLOGY, ISSN 1474-4422, 08/2007, Volume 6, Issue 8, pp. 734 - 746
The NINCDS-ADRDA and the DSM-IV-TR criteria for Alzheimer's disease (AD) are the prevailing diagnostic standards in research; however, they have now fallen... 
POSITRON-EMISSION-TOMOGRAPHY | BETA-AMYLOID PLAQUES | HIPPOCAMPAL ATROPHY | FRONTOTEMPORAL DEMENTIA | TEMPORAL-LOBE ATROPHY | MILD COGNITIVE IMPAIRMENT | CEREBROSPINAL-FLUID | HEALTHY ELDERLY PERSONS | PITTSBURGH COMPOUND-B | LEWY BODIES | CLINICAL NEUROLOGY
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 11/2009, Volume 1, Issue 8‐9, pp. 371 - 380
Alzheimer's disease (AD) pathology is estimated to develop many years before detectable cognitive decline. Fluid and imaging biomarkers may identify people in... 
amyloid | biomarker | preclinical Alzheimer's disease | Pittsburgh compound B | cerebrospinal fluid | Biomarker | Amyloid | Cerebrospinal fluid | Preclinical Alzheimer's disease | Report
Journal Article
NEUROLOGY, ISSN 0028-3878, 09/2009, Volume 73, Issue 10, pp. 754 - 760
Background: Patients with amnestic mild cognitive impairment (MCI) represent an important clinical group as they are at increased risk of developing Alzheimer... 
INDIVIDUALS | POSITRON-EMISSION-TOMOGRAPHY | DEMENTIA | PITTSBURGH-COMPOUND-B | ALZHEIMERS-DISEASE | DEPOSITION | LIGAND | MILD COGNITIVE IMPAIRMENT | CLINICAL NEUROLOGY | APOLIPOPROTEIN-E | TEMPORAL-LOBE
Journal Article
BRAIN, ISSN 0006-8950, 04/2016, Volume 139, pp. 1252 - 1264
While emerging evidence suggests that neuroinflammation plays a crucial role in Alzheimer's disease, the impact of the microglia response in Alzheimer's... 
biomarkers | QUANTIFICATION | RADIOLIGAND BINDING | NEUROSCIENCES | PITTSBURGH COMPOUND-B | CLINICAL NEUROLOGY | APP TRANSGENIC MICE | POSITRON-EMISSION-TOMOGRAPHY | TRANSLOCATOR PROTEIN | inflammation | NEUROINFLAMMATION | neuroprotection | AMYLOID-BETA | PERIPHERAL BENZODIAZEPINE-RECEPTOR | HIGH-RESOLUTION | Alzheimer's disease | microglia
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 04/2015, Volume 56, Issue 4, pp. 567 - 574
The accurate measurement of beta-amyloid (A beta) change using amyloid PET imaging is important for Alzheimer disease research and clinical trials but poses... 
amyloid | PET imaging | ALZHEIMERS-DISEASE | DEPOSITION | QUANTIFICATION | MILD COGNITIVE IMPAIRMENT | RADIOTRACERS | Alzheimer's disease | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PITTSBURGH COMPOUND-B | FLORBETAPIR F 18 | DECLINE
Journal Article
Annals of Neurology, ISSN 0364-5134, 10/2008, Volume 64, Issue 4, pp. 388 - 401
Objective Alzheimer's disease (AD) is found at autopsy in up to one third of patients with primary progressive aphasia (PPA), but clinical features that... 
C-11-PIB PET | ALZHEIMERS-DISEASE | SEMANTIC DEMENTIA | PATHOLOGY | HYPOMETABOLISM | FRONTOTEMPORAL LOBAR DEGENERATION | BINDING | NEUROSCIENCES | PITTSBURGH COMPOUND-B | BRAIN | CLINICAL NEUROLOGY | NONFLUENT APHASIA
Journal Article
ANNALS OF NEUROLOGY, ISSN 0364-5134, 03/2006, Volume 59, Issue 3, pp. 512 - 519
Objectives. Amyloid-beta(42) (A beta(42)) appears central to Alzheimer's disease (AD) pathogenesis and is a major component of amyloid plaques. Mean... 
ENTORHINAL CORTEX | DEMENTIA | METABOLISM | ALZHEIMERS-DISEASE | MOUSE MODEL | MILD COGNITIVE IMPAIRMENT | APOLIPOPROTEIN-E GENOTYPE | NEUROSCIENCES | PITTSBURGH COMPOUND-B | BRAIN | CLINICAL NEUROLOGY | AGE
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 04/2018, Volume 14, Issue 4, pp. 535 - 562
Journal Article