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Journal of the American Chemical Society, ISSN 0002-7863, 01/2016, Volume 138, Issue 3, pp. 962 - 968
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 08/2017, Volume 23, Issue 48, pp. 11570 - 11577
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2010, Volume 53, Issue 6, pp. 2636 - 2645
The PI3K/Akt signaling pathway is a key pathway in cell proliferation, growth, survival, protein synthesis, and glucose metabolism. It has been recognized... 
CHEMISTRY, MEDICINAL | ZSTK474 | 3-KINASE INHIBITOR | PATHWAY | 3-KINASE/MAMMALIAN TARGET | TUMOR-SUPPRESSOR | MUTATIONS | ANTITUMOR-ACTIVITY | IDENTIFICATION | CANCER | PTEN/MMAC1 | Neoplasms - metabolism | Models, Chemical | Area Under Curve | Humans | Neoplasms - prevention & control | Intracellular Signaling Peptides and Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Structure-Activity Relationship | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Adenosine Triphosphate - pharmacology | Protein Kinase Inhibitors - chemistry | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Inhibitory Concentration 50 | Female | Triazines - chemistry | Molecular Structure | Protein-Serine-Threonine Kinases - metabolism | Binding, Competitive | Protein Kinase Inhibitors - pharmacokinetics | Protein Structure, Tertiary | Cell Survival - drug effects | Triazines - pharmacology | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Models, Molecular | Morpholines - pharmacology | Morpholines - chemistry | Phosphatidylinositol 3-Kinases - genetics | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Survival Analysis | Cell Line, Tumor | Protein Binding | Mice | Protein Kinase Inhibitors - pharmacology | TOR Serine-Threonine Kinases | Morpholines - pharmacokinetics | Mutation | Adenosine Triphosphate - chemistry | Neoplasms - pathology | Triazines - pharmacokinetics
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 84, pp. 250 - 261
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2009, Volume 131, Issue 12, pp. 4216 - 4217
Journal Article
Journal Article
EMBO reports, ISSN 1469-221X, 07/2017, Volume 18, Issue 7, pp. 1100 - 1107
Journal Article