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Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2018, Volume 59, Issue 3, pp. 280 - 283
In this study we developed a novel copper-catalyzed O–H insertion of tetraethyl diphosphonodiazomethane into carboxylic acids, providing a simple method to... 
Insertion | Bone targeting | Prodrug | Bisphosphonates | Naproxen | CELLS | IN-VITRO | OSTEOMYELITIS | Prod rug | DRUG-DELIVERY | PRODRUGS | CHEMISTRY, ORGANIC | CONJUGATE | Drugs | Drug delivery systems | Analysis | Phosphonates | Copper | Methods | Organic acids | Vehicles
Journal Article
Synthesis, ISSN 0039-7881, 12/2014, Volume 46, Issue 23, pp. 3233 - 3238
Abstract Quaternary amino acids containing a geminal bisphosphonate moiety have been synthesized for the first time. The developed two-step reaction sequence... 
paper | Michael addition | geminal bisphosphonates | biologically relevant molecules | quaternary amino acids | azlactones | CATALYSIS | ASYMMETRIC-SYNTHESIS | CHEMISTRY, ORGANIC | ALDEHYDES | ENANTIOSELECTIVE MICHAEL ADDITION | VINYL PHOSPHONATES | ORGANOCATALYTIC CONJUGATE ADDITION | CONSTRUCTION | STEREOSELECTIVE-SYNTHESIS | OXAZOLONES | DERIVATIVES
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2010, Volume 25, Issue 3, pp. 606 - 616
Journal Article
Bone Reports, ISSN 2352-1872, 12/2018, Volume 9, pp. 47 - 60
Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease. The treatment of bone disorders... 
Infection | Osteomyelitis | Bone-targeting | Bisphosphonates | Drug conjugates | Cancer induced bone disease
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 12/2018, Volume 59, Issue 51, pp. 4528 - 4531
A dendritic bisphosphonate carrying three bisphosphonate (BP) units in close proximity was designed as a ligand to conjugate large therapeutic molecules for... 
Bisphosphonate | Conjugate | Bone targeting | Multivalent interaction | DRUG | ACID | CHEMISTRY, ORGANIC | AGENTS | PROTEINS | Phosphonates
Journal Article
Polymer Bulletin, ISSN 0170-0839, 08/2017, Volume 74, Issue 8, pp. 3161 - 3178
Polyaspartamides conjugates and co-conjugates containing platinum(II) complex and bisphosphonate were synthesized by stepwise reaction of polysuccinimide with... 
Antimalarial | Polyaspartamide | Bisphosphonate | Conjugate | Co-conjugate | Platinum complex | POLYMER SCIENCE | STAGE | CANCER | OSTEOPOROSIS | CHEMOTHERAPY | DELIVERY | TRIAL | THERAPY | PRODRUGS | MALARIA | PAGETS-DISEASE | Electron microscopy | Analysis
Journal Article
Journal of Materials Chemistry B, ISSN 2050-7518, 01/2015, Volume 3, Issue 2, pp. 250 - 259
Poly-hydroxy-aspartamide was used as a backbone to synthesize bisphosphonate derivatives thus achieving macromolecular carriers to be potentially used as... 
NANOPARTICLES | MATERIALS SCIENCE, BIOMATERIALS | ANTICANCER | METASTASES | BIODISTRIBUTION | COPOLYMERS | MICELLES | MODEL | ANTITUMOR-ACTIVITY | DERIVATIVES | Backbone | Binding | Conjugates | Drug delivery systems | Succinic acid | Bones | Derivatives | Spacers
Journal Article
Synthesis, ISSN 0039-7881, 05/2014, Volume 46, Issue 9, pp. 1129 - 1142
Journal Article