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Journal Article
Circulation (New York, N.Y.), ISSN 0009-7322, 05/2009, Volume 119, Issue 19, pp. 2568 - 2577
... metformin decreases cardiomyocyte apoptosis and attenuates the progression of heart failure in dogs... 
Heart failure | Metformin | AMP-activated protein kinase | Nitric oxide | heart failure | nitric oxide | CARDIAC & CARDIOVASCULAR SYSTEMS | ENDOTHELIAL NO SYNTHASE | BLOOD-GLUCOSE | metformin | ENDOPLASMIC-RETICULUM STRESS | DILATED CARDIOMYOPATHY | CONSCIOUS DOGS | NITRIC-OXIDE PRODUCTION | MYOCARDIAL FATTY-ACID | IN-VIVO | PERIPHERAL VASCULAR DISEASE | INDUCED CARDIAC-HYPERTROPHY | GLUCOSE-UPTAKE | HEMATOLOGY | Metformin - therapeutic use | Rats, Wistar | Apoptosis - drug effects | Heart Failure - enzymology | Nitric Oxide Synthase Type III - biosynthesis | Natriuretic Peptides - biosynthesis | Aminoimidazole Carboxamide - pharmacology | Cardiotonic Agents - therapeutic use | Myocytes, Cardiac - enzymology | Ribonucleotides - pharmacology | Protein Processing, Post-Translational - drug effects | Ventricular Dysfunction, Left - genetics | Ultrasonography | Ventricular Dysfunction, Left - enzymology | Heart Failure - diagnostic imaging | Phosphorylation - drug effects | Drug Evaluation, Preclinical | Transforming Growth Factor beta1 - biosynthesis | Natriuretic Peptides - genetics | Pyrazoles - pharmacology | Nitric Oxide - biosynthesis | Cells, Cultured - drug effects | AMP-Activated Protein Kinases - antagonists & inhibitors | Insulin Resistance | Rats | Transforming Growth Factor beta1 - genetics | Pyrimidines - pharmacology | Nitric Oxide Synthase Type III - genetics | Cells, Cultured - enzymology | Disease Progression | Ventricular Dysfunction, Left - diagnostic imaging | Heart Failure - drug therapy | Gene Expression Regulation - drug effects | AMP-Activated Protein Kinases - physiology | Animals | Myocytes, Cardiac - drug effects | Ventricular Dysfunction, Left - drug therapy | Aminoimidazole Carboxamide - analogs & derivatives | Dogs | Fibrosis | Oxidative Stress - drug effects | Prevention | Oxidative stress | Usage | Demographic aspects | Animal models in research | Physiological aspects | Dosage and administration | Cyclic adenylic acid | Research | Protein kinases
Journal Article
Veterinary ophthalmology, ISSN 1463-5224, 2019, Volume 22, Issue 6, pp. 767 - 777
...) in conscious, healthy dogs utilizing contrast‐enhanced ultrasonography (CEUS); to compare varying enhancement with the first and second bolus injection and in the right and left eye... 
conscious dogs | perfusion parameters | SonoVue | sulfur hexafluoride | canine eyes | contrast‐enhanced ultrasonography | contrast-enhanced ultrasonography | Animals | Contrast Media | Dogs - physiology | Male | Ultrasonography - veterinary | Sulfur Hexafluoride | Eye - diagnostic imaging | Ultrasonography - methods | Original
Journal Article
Journal Article
Journal Article
Journal of cardiovascular pharmacology, ISSN 0160-2446, 06/2011, Volume 57, Issue 6, pp. 639 - 647
... (HR) in the absence and presence of hexamethonium (a ganglionic blocker) were studied in conscious dogs. Ranolazine (0.4, 1.2... 
conscious dogs | ranolazine | antiadrenergic effect | coronary blood flow | hemodynamics | LATE SODIUM CURRENT | CARDIAC & CARDIOVASCULAR SYSTEMS | ANTIANGINAL AGENT | ISCHEMIA | RANDOMIZED CONTROLLED-TRIAL | ACUTE-CORONARY-SYNDROME | INHIBITION | ANGINA | THROMBOLYSIS | PHARMACOLOGY & PHARMACY | Acetanilides - metabolism | Piperazines - administration & dosage | Isoproterenol - toxicity | Adrenergic Antagonists - metabolism | Acetanilides - administration & dosage | Isoproterenol - administration & dosage | Hypertension - drug therapy | Piperazines - metabolism | Vasoconstrictor Agents - toxicity | Ganglionic Blockers - pharmacology | Phenylephrine - administration & dosage | Ranolazine | Dose-Response Relationship, Drug | Heart Rate - drug effects | Hexamethonium - pharmacology | Hypotension - drug therapy | Adrenergic Antagonists - therapeutic use | Hypertension - chemically induced | Acetanilides - therapeutic use | Piperazines - blood | Receptors, Adrenergic, beta - metabolism | Receptors, Adrenergic, alpha - metabolism | Receptors, Adrenergic, beta - chemistry | Vasoconstrictor Agents - administration & dosage | Guinea Pigs | Phenylephrine - toxicity | Adrenergic Antagonists - administration & dosage | Rats | Piperazines - therapeutic use | Receptors, Adrenergic, alpha - chemistry | Autonomic Agents - therapeutic use | Hypotension - chemically induced | Autonomic Agents - administration & dosage | Animals | Vasodilator Agents - toxicity | Adrenergic Antagonists - blood | Dogs | Acetanilides - blood | Hemodynamics - drug effects | Coronary Circulation - drug effects | Kinetics | Vasodilator Agents - administration & dosage
Journal Article
Comparative medicine, ISSN 1532-0820, 04/2005, Volume 55, Issue 2, pp. 156 - 161
The purpose of this project was to collate canine cardiopulmonary measurements from published and unpublished studies in our laboratory in 97 instrumented, unsedated, normovolemic dogs. Body weight... 
ACID-BASE STATUS | CONSCIOUS DOGS | O-2 UPTAKE | ANESTHETIZED DOGS | ENERGY-EXPENDITURE | ZOOLOGY | PATHOLOGICAL SUPPLY DEPENDENCE | ARTERIAL BLOOD-GASES | BODY OXYGEN-CONSUMPTION | HYPOVOLEMIC DOGS | VETERINARY SCIENCES | UNANESTHETIZED DOGS | Cardiovascular Physiological Phenomena | Animals | Dogs - physiology | Reference Values | Data Collection | Respiratory Function Tests | Lung - physiology | Cardiovascular System
Journal Article
Journal Article
Journal Article