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Critical Reviews in Toxicology, ISSN 1040-8444, 1/2014, Volume 44, Issue 1, pp. 64 - 82
Journal Article
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 07/2014, Volume 33, Issue 28, pp. 3717 - 3729
.... The constitutive androstane receptor (CAR), a xenosensor, is a key regulator of MDR. It functions in xenobiotic detoxification by regulating the expression of phase I drug-metabolizing enzymes and ATP-binding cassette (ABC... 
microRNA | MDR1 | miR-137 | doxorubicin | constitutive androstane receptor | PROMOTER METHYLATION | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG-RESISTANCE | INDUCTION | CELL BIOLOGY | AMPLIFICATION | LIVER-INJURY | ONCOLOGY | IN-VIVO | GENETICS & HEREDITY | GENE-EXPRESSION | MULTIDRUG-RESISTANCE | MICRORNA EXPRESSION | Humans | Male | MicroRNAs - metabolism | Promoter Regions, Genetic - drug effects | Promoter Regions, Genetic - genetics | Neuroblastoma - physiopathology | Base Sequence | Antineoplastic Agents - pharmacology | Neuroblastoma - pathology | Neuroblastoma - genetics | DNA Methylation - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Down-Regulation - drug effects | Down-Regulation - genetics | Drug Resistance, Neoplasm - genetics | Animals | Cell Transformation, Neoplastic | Cell Line, Tumor | Feedback, Physiological - drug effects | Cell Proliferation - drug effects | Mice | MicroRNAs - genetics | Neuroblastoma - metabolism | ATP Binding Cassette Transporter, Sub-Family B - genetics | DNA Methylation - drug effects | Doxorubicin - pharmacology | Receptors, Cytoplasmic and Nuclear - metabolism | Cell receptors | MicroRNA | Genetic research | Genetic aspects | Dosage and administration | Neuroblastoma | Research | Drug resistance | Drug therapy | Genetic regulation | Health aspects | Doxorubicin | Nervous system | Chemotherapy | Gene expression | MicroRNAs | Cancer
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 10/2011, Volume 31, Issue 10, pp. 2232 - 2239
OBJECTIVE—The goal of this study was to determine the impact of the nuclear receptor constitutive androstane receptor (CAR... 
atherosclerosis | constitutive androstane receptor | lipoproteins | BILE-ACID | FAMILIAL HYPERCHOLESTEROLEMIA | MOUSE | PREGNANE-X-RECEPTOR | VLDL RECEPTOR | GENE | CHOLESTEROL TRANSPORT | CAR | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | DRUG-METABOLISM | TRANSGENIC MICE | Hyperlipidemias - genetics | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Cholesterol - blood | Humans | Molecular Sequence Data | Apolipoproteins B - blood | RNA, Messenger - metabolism | Transfection | Lipogenesis - genetics | Time Factors | HEK293 Cells | Receptors, LDL - deficiency | Cholesterol, LDL - blood | Female | Genes, Reporter | Disease Models, Animal | Amino Acid Sequence | Receptors, LDL - genetics | Atherosclerosis - pathology | Hyperlipidemias - metabolism | Response Elements | Down-Regulation | Liver - metabolism | Mice, Inbred C57BL | Receptors, LDL - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Lipoproteins - blood | Hyperlipidemias - prevention & control | Atherosclerosis - metabolism | Hep G2 Cells | Mice, Knockout | Animals | Lipoproteins, VLDL - blood | Apolipoproteins E - genetics | Triglycerides - blood | Hyperlipidemias - pathology | Mice | Pyridines - pharmacology | Atherosclerosis - prevention & control | Receptors, Cytoplasmic and Nuclear - metabolism | Life Sciences | Biochemistry, Molecular Biology
Journal Article
World journal of gastroenterology : WJG, ISSN 1007-9327, 2017, Volume 23, Issue 42, pp. 7519 - 7530
...(CYP3 A1 and CYP3 A2) and of pregnane X receptor(PXR) and constitutive androstane receptor... 
Drug metabolism | CYP3A | Constitutive androstane receptor | Pregnane X receptor | Cholestasis
Journal Article