X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2626) 2626
Book Review (552) 552
Publication (415) 415
Book Chapter (34) 34
Conference Proceeding (9) 9
Government Document (1) 1
Presentation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (2183) 2183
humans (1649) 1649
constitutive activation (1494) 1494
animals (1137) 1137
phosphorylation (723) 723
oncology (705) 705
biochemistry & molecular biology (658) 658
cell biology (602) 602
mice (571) 571
signal transduction (532) 532
apoptosis (497) 497
cell line, tumor (424) 424
female (387) 387
proteins (354) 354
cancer (343) 343
male (336) 336
expression (314) 314
gene-expression (276) 276
pharmacology & pharmacy (271) 271
stat3 (267) 267
research (259) 259
gene expression (255) 255
mutation (248) 248
stat3 transcription factor - metabolism (246) 246
article (232) 232
cell line (231) 231
apoptosis - drug effects (228) 228
constitutive activity (222) 222
hematology (222) 222
signal transduction - drug effects (216) 216
physiological aspects (208) 208
constitutive androstane receptor (204) 204
kinases (201) 201
nf-kappa-b (196) 196
analysis (191) 191
in-vivo (189) 189
dna-binding proteins - metabolism (184) 184
transcription factors (181) 181
cells (180) 180
genetic aspects (174) 174
constitutive expression (172) 172
molecular sequence data (172) 172
genetics & heredity (171) 171
rats (161) 161
trans-activators - metabolism (161) 161
tumor cells, cultured (157) 157
amino acid sequence (155) 155
cell proliferation (153) 153
transfection (152) 152
antineoplastic agents - pharmacology (151) 151
blotting, western (150) 150
cell proliferation - drug effects (147) 147
health aspects (147) 147
growth (146) 146
phosphorylation - drug effects (145) 145
stat3 transcription factor (145) 145
activation (142) 142
protein binding (141) 141
middle aged (136) 136
signal-transduction (135) 135
research article (134) 134
leukemia (133) 133
down-regulation (132) 132
cells, cultured (131) 131
immunohistochemistry (131) 131
multidisciplinary sciences (131) 131
transcription factor (131) 131
tumors (131) 131
signal transducer (130) 130
cell cycle (128) 128
signal transduction - physiology (127) 127
inhibition (125) 125
gene expression regulation, neoplastic (121) 121
adult (120) 120
aged (119) 119
gene (119) 119
in-vitro (119) 119
models, biological (118) 118
protein (118) 118
transcription (118) 118
biophysics (114) 114
breast-cancer (114) 114
abridged index medicus (113) 113
immunology (113) 113
endocrinology & metabolism (112) 112
acute myeloid-leukemia (111) 111
pathway (110) 110
ligands (109) 109
pregnane-x-receptor (109) 109
proliferation (107) 107
genes (101) 101
stat3 transcription factor - genetics (101) 101
base sequence (98) 98
medicine (98) 98
neurosciences (96) 96
breast cancer (95) 95
care and treatment (95) 95
enzyme inhibitors - pharmacology (94) 94
protein-tyrosine kinases - metabolism (93) 93
tyrosine kinase (93) 93
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Biological Chemistry, ISSN 0021-9258, 02/2012, Volume 287, Issue 9, pp. 6668 - 6678
Activity of heparanase is implicated strongly in dissemination of metastatic tumor cells and cells of the immune system. In addition, heparanase enhances the... 
LOCALIZATION | REGULATOR | PROTEOGLYCANS | METASTASIS | TUMOR PROGRESSION | CONSTITUTIVE ACTIVATION | SULFATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | EXPRESSION | CONTRIBUTES | Phosphorylation - physiology | Prostatic Neoplasms - metabolism | Fibroblasts - enzymology | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Glucuronidase - metabolism | Male | Head and Neck Neoplasms - metabolism | Breast Neoplasms - metabolism | Laryngeal Neoplasms - pathology | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptor, Epidermal Growth Factor - metabolism | STAT1 Transcription Factor - metabolism | Tumor Suppressor Proteins - genetics | Female | Nose Neoplasms - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Tongue Neoplasms - metabolism | Prostatic Neoplasms - pathology | Nose Neoplasms - pathology | Tumor Suppressor Proteins - metabolism | Laryngeal Neoplasms - metabolism | Cells, Cultured | Multiple Myeloma - metabolism | STAT1 Transcription Factor - genetics | Tongue Neoplasms - pathology | Disease Progression | Head and Neck Neoplasms - pathology | Multiple Myeloma - pathology | Animals | Breast Neoplasms - pathology | Fibroblasts - cytology | Mice | Index Medicus | Phosphorylation | Epidermal Growth Factor Receptor (EGFR) | STAT3 | Cell Signaling | Heparan Sulfate | Heparanase | Glycosaminoglycan | Glycobiology and Extracellular Matrices | Cancer Biology | Head And Neck Cancer | Localization
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2015, Volume 470, Issue 2, pp. 207 - 221
The mammalian or mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) is a ubiquitously expressed multimeric protein kinase complex that integrates... 
Sodium-coupled neutral amino acid transporter 2 (SNAT2) | Amino acid | Growth | Transcription factor EB (TFEB) | L-type (leucine) amino acid transporter 1 (LAT1) | Uncoordinated-51-like kinase (ULK1) | Leucine | Proliferation | Autophagy | Insulin | p70S6K1 | leucine | MAMMALIAN TARGET | autophagy | PROTEIN | insulin | proliferation | amino acid | MTOR COMPLEX 1 | CONSTITUTIVE ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TSC2 | SYNTHASE KINASE 3 | GAP ACTIVITY | uncoordinated-51-like kinase (ULK1) | RAPAMYCIN MTOR | SKELETAL-MUSCLE CELLS | transcription factor EB (TFEB) | growth | sodium-coupled neutral amino acid transporter 2 (SNAT2) | RNA, Small Interfering - genetics | Phosphorylation | Cell Proliferation | TOR Serine-Threonine Kinases - metabolism | Humans | Molecular Sequence Data | Mechanistic Target of Rapamycin Complex 1 | Amino Acids - metabolism | Multiprotein Complexes - metabolism | Lysosomes - metabolism | Regulatory-Associated Protein of mTOR | Amino Acid Sequence | Cell Line | Signal Transduction | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Gene Silencing | Rats | Serine - genetics | Glycogen Synthase Kinase 3 - metabolism | Serine - metabolism | Animals | Glycogen Synthase Kinase 3 - genetics | Adaptor Proteins, Signal Transducing - genetics | Mice | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus
Journal Article
Cellular Signalling, ISSN 0898-6568, 2010, Volume 22, Issue 11, pp. 1645 - 1654
IκB kinase β (IKKβ) plays a crucial role in biological processes, including immune response, stress response, and tumor development by mediating the activation... 
NF-κB signaling | KEAP1 | TNFα | IKKβ | Autophagy | HSP90 | OXIDATIVE STRESS | TNF alpha | PROTEIN | PROTEASOMAL DEGRADATION | TRANSCRIPTION | CONSTITUTIVE NRF2 ACTIVATION | CELL BIOLOGY | E3 LIGASE | LUNG-CANCER | IKK beta | PATHWAY | KINASE IKK | NF-kappa B signaling
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 06/2011, Volume 10, Issue 6, pp. 960 - 971
Journal Article
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 02/2006, Volume 203, Issue 2, pp. 371 - 381
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2011, Volume 286, Issue 13, pp. 11456 - 11468
Journal Article
Leukemia, ISSN 0887-6924, 12/2007, Volume 21, Issue 12, pp. 2476 - 2484
Deregulated accumulation of nuclear beta-catenin enhances transcription of beta-catenin target genes and promotes malignant transformation. Recently, acute... 
beta-catenin | MULTIPLE-MYELOMA | INTERNAL TANDEM DUPLICATION | FLT3 AML | CYCLIN D1 | CONSTITUTIVE ACTIVATION | KINASE INHIBITOR | COLON-CARCINOMA CELLS | HEMATOPOIETIC-CELLS | ONCOLOGY | SIGNALING PATHWAY | tyrosine phosphorylation | HEMATOLOGY | HEMATOLOGIC MALIGNANCIES | UBIQUITIN-PROTEASOME PATHWAY | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Glycogen Synthase Kinase 3 - physiology | Phosphorylation | Active Transport, Cell Nucleus - physiology | fms-Like Tyrosine Kinase 3 - physiology | Humans | Leukemia, Myeloid - genetics | Neoplasm Proteins - physiology | Glycogen Synthase Kinase 3 beta | Neoplasm Proteins - antagonists & inhibitors | Staurosporine - analogs & derivatives | Membrane Proteins - pharmacology | Interleukin-3 - pharmacology | Phosphotyrosine - metabolism | Leukemia, Myeloid - pathology | fms-Like Tyrosine Kinase 3 - genetics | Recombinant Proteins - metabolism | Acute Disease | Glycogen Synthase Kinase 3 - antagonists & inhibitors | RNA, Small Interfering - pharmacology | Tyrphostins - pharmacology | Gene Expression Regulation, Leukemic | beta Catenin - metabolism | Protein Processing, Post-Translational - physiology | beta Catenin - genetics | Transcription, Genetic - physiology | Animals | Leukemia, Myeloid - metabolism | Cell Line, Tumor | Mice | Staurosporine - pharmacology | Index Medicus
Journal Article
Science, ISSN 0036-8075, 8/1998, Volume 281, Issue 5381, pp. 1360 - 1363
A large protein complex mediates the phosphorylation of the inhibitor of κB (IκB), which results in the activation of nuclear factor κB (NF-κB). Two subunits... 
Phosphorylation | Elution | Immunoprecipitation | Gels | HeLa cells | Antibodies | Viruses | Immunoblotting | Reports | Infections | Dimers | SIGNAL | ACTIVATION | DISSOCIATION | CONSTITUTIVE PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DEGRADATION | CASEIN KINASE-II | PROTEOLYSIS | TRANSCRIPTION FACTOR | SUFFICIENT | EXPRESSION
Journal Article