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Journal of the American College of Cardiology, ISSN 0735-1097, 07/2015, Volume 66, Issue 3, pp. 278 - 307
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 483, Issue 7391, pp. 613 - 617
...), has not been fully explored. Here we use genetically engineeredmousemodels to conduct a ` co-clinical' trial that mirrors an ongoing human clinical trial in patients with KRAS-mutant lung cancers... 
SURVIVAL | VOLUME MEASUREMENT | GEFITINIB | ACTIVATION | METAANALYSIS | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | ARRY-142886 | STANDARDIZED UPTAKE VALUE | DOCETAXEL | MOUSE MODELS | Lung Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - deficiency | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Lung Neoplasms - metabolism | ras Proteins - metabolism | Tomography, X-Ray Computed | Positron-Emission Tomography | Taxoids - therapeutic use | Biomarkers, Tumor - metabolism | Drug Evaluation, Preclinical | Benzimidazoles - therapeutic use | Disease Models, Animal | Proto-Oncogene Proteins p21(ras) - metabolism | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Pharmacogenetics - methods | Reproducibility of Results | Lung Neoplasms - enzymology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - genetics | Antineoplastic Combined Chemotherapy Protocols | Proto-Oncogene Proteins - genetics | Treatment Outcome | Genes, p53 - genetics | Mutation - genetics | Randomized Controlled Trials as Topic | Animals | MAP Kinase Signaling System - drug effects | Benzimidazoles - pharmacology | Fluorodeoxyglucose F18 | Biomarkers, Tumor - genetics | Mice | Clinical Trials, Phase II as Topic | Antimitotic agents | Gene mutations | Genetic aspects | Dosage and administration | Research | Lung cancer, Non-small cell | Drug therapy | Antineoplastic agents | Health aspects | Confidence intervals | Hypotheses | Clinical trials | Tomography | Mutation | Pharmaceutical industry | Drug dosages | Cancer therapies | Patients | Tumors | Apoptosis
Journal Article
European urology, ISSN 0302-2838, 2015, Volume 67, Issue 6, pp. 1042 - 1050
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 12/2003, Volume 168, Issue 12, pp. 1438 - 1444
Journal Article
The American heart journal, ISSN 0002-8703, 2012, Volume 163, Issue 4, pp. 541 - 548
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2011, Volume 70, Issue 6, pp. 1003 - 1009
Journal Article