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Journal Article
Pharmacological Research, ISSN 1043-6618, 04/2018, Volume 130, pp. 1 - 11
[Display omitted] After more than a decade of intense investigation, Pro-protein Convertase Subtilisin-Kexin type 9 (PCSK9) remains a hot topic of research... 
Monoclonal antibodies | PCSK9 | Lipoproteins | Triglycerides | Metabolism | Animals | Humans | Lipoproteins - metabolism | Receptors, LDL - metabolism | Proprotein Convertase 9 - genetics | Proprotein Convertase 9 - metabolism | Triglycerides - metabolism
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 06/2010, Volume 51, Issue 6, pp. 1486 - 1495
We investigated the role of proprotein convertase subtilisin/kexin type 9 (PCSK9) in the resistance of dyslipidemic hamsters to statin-induced LDL-cholesterol... 
Berberine | Rosuvastatin | LDL receptor | INSULIN-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CONVERTASE SUBTILISIN/KEXIN TYPE-9 | HEPG2 CELLS | PROPROTEIN-CONVERTASE-SUBTILISIN/KEXIN-TYPE-9 | ANIMAL-MODEL | rosuvastatin | BINDING | berberine | DENSITY-LIPOPROTEIN RECEPTOR | ATORVASTATIN
Journal Article
Journal Article
Annual Review of Pharmacology and Toxicology, ISSN 0362-1642, 1/2017, Volume 57, Issue 1, pp. 223 - 244
Proprotein convertase subtilisin kexin type-9 (PCSK9) is a secreted zymogen expressed primarily in the liver. PCSK9 circulates in plasma, binds to cell surface... 
PCSK9 inhibitors | cardiovascular disease | proprotein convertase subtilisin kexin type-9 | low-density lipoprotein receptor | low-density lipoprotein cholesterol | Cardiovascular disease | Low-density lipoprotein receptor | Proprotein convertase subtilisin/kexin type-9 | Low-density lipoprotein cholesterol | PROPROTEIN CONVERTASE | EVOLOCUMAB AMG 145 | AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA | SUBTILISIN/KEXIN TYPE 9 | ACUTE CORONARY SYNDROMES | MONOCLONAL-ANTIBODY | proprotein convertase subtilisin/kexin type-9 | HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA | DENSITY-LIPOPROTEIN-RECEPTOR | REDUCES LDL-CHOLESTEROL | PHARMACOLOGY & PHARMACY | TOXICOLOGY | PLACEBO-CONTROLLED TRIAL | Dyslipidemias - drug therapy | Hypercholesterolemia - blood | Enzyme Inhibitors - metabolism | Humans | Cholesterol, LDL - antagonists & inhibitors | Drug Discovery - trends | Drug Discovery - methods | Hypercholesterolemia - drug therapy | Dyslipidemias - enzymology | Enzyme Inhibitors - administration & dosage | Dyslipidemias - blood | Animals | Proprotein Convertase 9 - antagonists & inhibitors | Hypercholesterolemia - enzymology | Cholesterol, LDL - blood | Proprotein Convertase 9 - physiology | Drug Delivery Systems - trends | Drug Delivery Systems - methods | Laws, regulations and rules | Low density lipoproteins | Atherosclerosis | Index Medicus
Journal Article