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Journal of Organic Chemistry, ISSN 0022-3263, 2019, Volume 84, Issue 13, pp. 8542 - 8551
Five new dibenzocyclooctynes bearing different substituents on their aryl moieties were synthesized and evaluated for their reactivity toward strain-promoted... 
CHEMISTRY, ORGANIC | FREE CLICK CHEMISTRY | COPPER-FREE
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 04/2015, Volume 13, Issue 13, pp. 3866 - 3870
We present the concept, synthesis, and kinetic characterization of PYRROC as the first functionalized cycloalkyne which cannot form isomers in the reaction... 
CHEMISTRY, ORGANIC | COPPER-FREE | EFFICIENT | CYCLOADDITIONS
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 05/2011, Volume 52, Issue 20, pp. 2566 - 2570
An efficient, copper-free Sonogashira coupling reaction of 1-chloroisoquinolines and terminal alkynes, catalyzed by Pd(OAc) /Ruphos, in the presence of Et N... 
Sonogashira coupling | 1-Alkynyl-3-substituted isoquinolines | Ruphos | Copper-free
Journal Article
Chemical Communications, ISSN 1359-7345, 02/2012, Volume 48, Issue 12, pp. 1736 - 1738
Substituted tetrazines have been found to undergo facile inverse electron demand Diels-Alder reactions with "tunable'' reaction rates. 
CYCLOADDITION | DESIGN | CHEMISTRY | LIGATION | COPPER-FREE | SELECTIVITY | ALKYNE | CHEMISTRY, MULTIDISCIPLINARY | LIVING CELLS | Index Medicus
Journal Article
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 03/2019, Volume 84, Issue 6, pp. 3590 - 3594
A porphyrin-containing polymer exhibiting various degrees of Glaser-Hay coupling is reported. Sonogashira polycondensation of zinc(II) (5, 15-bis [ 3,4,5 -tri... 
CHEMISTRY, ORGANIC | COPOLYMERS | COPPER-FREE | CONJUGATED POLYMERS | SOLVENT
Journal Article
by Moon, J and Jeong, M and Nam, H and Ju, J and Moon, JH and Jung, HM and Lee, S
ORGANIC LETTERS, ISSN 1523-7060, 03/2008, Volume 10, Issue 5, pp. 945 - 948
Decarboxylative coupling of sp-sp(2) carbons is possible by palladium catalyst. Employing propiolic acid (1) as a difunctional alkyne, and using the... 
HECK | AMINE-FREE | ARYL HALIDES | CHEMISTRY, ORGANIC | TERMINAL ALKYNES | COPPER-FREE
Journal Article
Biomaterials, ISSN 0142-9612, 01/2014, Volume 35, Issue 4, pp. 1257 - 1266
Porous silicon (PSi) has been demonstrated as a promising drug delivery vector for poorly water-soluble drugs. Here, a simple and efficient method based on... 
Surface modification | Intracellular uptake | Cancer therapy | Porous silicon nanoparticle | Drug delivery | Copper-free click chemistry
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5378 - 5378
Strain-promoted azide-alkyne cycloaddition (SPAAC) as a conjugation tool has found broad application in material sciences, chemical biology and even in vivo... 
DENSITY | SURFACE FUNCTIONALIZATION | MULTIDISCIPLINARY SCIENCES | LIGATION | BIOORTHOGONAL CHEMISTRY | COPPER-FREE | BICYCLONONYNES | FREE CLICK CHEMISTRY | ALKYNE CYCLOADDITION | LIVING CELLS
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 08/2016, Volume 81, Issue 15, pp. 6816 - 6819
We investigate the effect of buffer identity, ionic strength, pH, and organic cosolvents on the rate of strain promoted azide-alkyne cycloaddition with the... 
CHEMISTRY | SURFACE | CHEMISTRY, ORGANIC | COPPER-FREE | LIVING CELLS
Journal Article
Organic Letters, ISSN 1523-7060, 07/2014, Volume 16, Issue 14, pp. 3724 - 3727
A general protocol for the Sonogashira reaction using a 100:1 combination of (N-heterocyclic carbene)-Cu and (N-heterocyclic carbene)-Pd complexes is... 
ARYL BROMIDES | PPB LEVELS | HECK | CHLORIDES | CHEMISTRY, ORGANIC | AIR | MIXED AQUEOUS-MEDIUM | COPPER-FREE | EFFICIENT
Journal Article
Green Chemistry, ISSN 1463-9262, 10/2012, Volume 14, Issue 10, pp. 2840 - 2855
The high surface area of 2D-hexagonal periodic mesoporous organosilica (PMO) containing a phloroglucinol-diimine moiety inside the pore wall has been utilized... 
ARYL BROMIDES | HALIDES | ROOM-TEMPERATURE | PALLADIUM | CROSS-COUPLINGS | LIGAND-FREE | COPPER-FREE | SILICA | CHEMISTRY, MULTIDISCIPLINARY | SUZUKI-MIYAURA | WATER
Journal Article
Angewandte Chemie - International Edition Angewandte Chemie - International Edition, ISSN 0570-0833, 2009, Volume 48, Issue 27, pp. 4900 - 4908
Journal Article
Macromolecules, ISSN 0024-9297, 08/2011, Volume 44, Issue 16, pp. 6424 - 6432
The synthesis of a new multifunctional copoly(2-oxazoline) scaffold containing a-anthracene and omega-azide termini as well as pendant alkene groups in the... 
POLYMERS | CYCLOADDITION | CONJUGATION | POLYMER SCIENCE | LECTIN | BLOCK-COPOLYMERS | WELL | CHEMISTRY | RADICAL POLYMERIZATION | COPPER-FREE
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 10/2011, Volume 40, Issue 10, pp. 5084 - 5121
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 96, pp. 13499 - 13502
Introduction of an amino group at the para position of doubly sterically-hindered aryl azides significantly enhances the reactivity with cyclooctynes. The... 
1,3-DIPOLAR CYCLOADDITIONS | ACTIVATION | CLICK CHEMISTRY | LIGATION | STRAINED ALKYNES | DISTORTION/INTERACTION | COPPER-FREE | CHEMISTRY, MULTIDISCIPLINARY | PROBES
Journal Article
Chemical Communications, ISSN 1359-7345, 2019, Volume 55, Issue 24, pp. 3556 - 3559
A facile method for preparing various functional cycloalkynes, including proteins incorporated with a cycloalkyne moiety, from the corresponding azides is... 
1,3-DIPOLAR CYCLOADDITIONS | PROTECTION | CLICK CHEMISTRY | COPPER-FREE | DIYNE | ALKYNES | STRAIN | CHEMISTRY, MULTIDISCIPLINARY | PAIRS | Index Medicus
Journal Article