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Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 12, pp. 1757 - 1768
The pentacyclic triterpenoid ursolic acid was previously shown to inhibit the intracellular trafficking of intercellular adhesion molecule-1 (ICAM-1) from the... 
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 12, pp. 1757 - 1768
The pentacyclic triterpenoid ursolic acid was previously shown to inhibit the intracellular trafficking of intercellular adhesion molecule-1 (ICAM-1) from the... 
asiatic acid | intracellular trafficking | maslinic acid | corosolic acid | pentacyclic triterpenoid | intercellular adhesion molecule-1 | Asiatic acid | Maslinic acid | Pentacyclic triterpenoid | Corosolic acid | Intercellular adhesion molecule-1 | Intracellular trafficking | CELLS | INDUCED INFLAMMATORY RESPONSE | ALPHA-GLUCOSIDASE | FACTOR-KAPPA-B | URSOLIC ACID | IN-VITRO | INHIBITION | BETULINIC ACID | SIGNALING PATHWAY | PHARMACOLOGY & PHARMACY | PENTACYCLIC TRITERPENOIDS | A549 Cells | Triterpenes - pharmacology | Golgi Apparatus - drug effects | Humans | Endoplasmic Reticulum - metabolism | Pentacyclic Triterpenes - pharmacology | Glycosylation - drug effects | Polysaccharides - metabolism | Protein Transport | Microscopy, Confocal | Intercellular Adhesion Molecule-1 - metabolism | Endoplasmic Reticulum - drug effects | Intercellular Adhesion Molecule-1 - genetics | Endoplasmic Reticulum - immunology | Golgi Apparatus - metabolism | Golgi Apparatus - immunology | Cytokines - immunology | Adenocarcinoma | Yeast | Intercellular adhesion molecule 1 | Jack beans | Triterpenoids | Interleukin | Endoglycosidase H | Glucosidase | Glycosylation | Calnexin | Cell surface | Adhesion | Mannosidase | Golgi apparatus | Polysaccharides | Acids | Lungs | Cell adhesion | Ursolic acid | Intracellular | Transport | Localization | Endoplasmic reticulum | Pentacyclic triterpenoids
Journal Article
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 05/2019, Volume 86, pp. 277 - 287
Pentacyclic dihydroxyterpene carboxylic acid derivatives were obtained by coupling with -amino acids at C-28 position. Compare to the parent compounds ( or ),... 
Water solubility | α-Glucosidase inhibitory activities | Maslinic acid | Corosolic acid | l-amino acids | L-amino acids
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2019, Volume 378, p. 114600
Corosolic acid (CRA) has been widely used as a food supplement. However, its pharmacokinetic behavior still needs to be explored. In this study, the absorption... 
Corosolic acid | in situ gastric absorption | metabolite identification | in situ single-pass perfusion | PLASMA | APOPTOTIC CELL-DEATH | PASS INTESTINAL PERFUSION | LEAVES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TRITERPENES | EXTRACT
Journal Article
Journal Article
by Zeng, Z and Yin, XL and Wang, XY and Yang, WY and Liu, XQ and Hong, YP
BIOORGANIC CHEMISTRY, ISSN 0045-2068, 05/2019, Volume 86, pp. 277 - 287
Twenty maslinic acid and corosolic acid derivatives were obtained by coupling with L-amino acids at C-28 position. The alpha-glucosidase inhibitory activities... 
L-amino acids | GLUCOSIDASE INHIBITION | GLYCOGEN-PHOSPHORYLASE INHIBITOR | Maslinic acid | Corosolic acid | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | BLOOD-GLUCOSE | CHEMISTRY, ORGANIC | CYTOTOXIC ACTIVITY | MOLECULAR DOCKING | alpha-Glucosidase inhibitory activities | BETULINIC ACID | Water solubility | BIOLOGICAL EVALUATION
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 04/2018, Volume 57, Issue 4, pp. 512 - 521
Corosolic acid (CRA) is found in various plants and has been used as a health food supplement worldwide. Although it has been reported that CRA exhibits... 
DNMT | Nrf2 | corosolic acid | methylation | HDAC | CARCINOMA-CELLS | CURCUMIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | URSOLIC ACID | COLON-CANCER CELLS | IN-VITRO | C1 CELLS | ONCOLOGY | INCREASED SUSCEPTIBILITY | PATHWAY | MICE | EXPRESSION | Cell Line | Triterpenes - pharmacology | Histone Deacetylases - genetics | Histone Deacetylases - metabolism | Male | Prostate - metabolism | DNA (Cytosine-5-)-Methyltransferases - metabolism | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Prostatic Neoplasms - genetics | RNA Interference | Cell Transformation, Neoplastic - genetics | NF-E2-Related Factor 2 - metabolism | Prostate - cytology | NF-E2-Related Factor 2 - genetics | Epigenesis, Genetic - drug effects | Mice | Cell Transformation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | DNA Methylation - drug effects | Sulfites | Epigenetic inheritance | Chromatin | Methyltransferases | RNA | Lysine | Analysis | Dietary supplements | Heme | Methylation | Prostate cancer | Quinone oxidoreductase | Transformation | Bisulfite | Immunoprecipitation | Oxidoreductase | Activation | mRNA | Gene sequencing | Anticancer properties | DNA methylation | Acetylation | NRF2 protein | Deoxyribonucleic acid--DNA | CpG islands | Quinone | Gene expression | NAD | Oxygenase | Acids | Epigenetics | Antitumor activity | Protein expression | Prostate | Histone H3 | DNA sequencing | Cancer | Corosolic acid
Journal Article
Cancer Letters, ISSN 0304-3835, 2009, Volume 284, Issue 2, pp. 229 - 237
Abstract We investigated the response of human cervix adenocarcinoma HeLa cells to Corosolic acid (CRA) treatment. Our results showed that CRA significantly... 
Hematology, Oncology and Palliative Medicine | Caspase | Cervix adenocarcinoma | Mitochondria | Corosolic acid | Apoptosis | CANCER-CELLS | TRITERPENOIDS | DEATH | CYTOCHROME-C | URSOLIC ACID | ARREST | ONCOLOGY | GROWTH | TARGETS | STRESS | Adenocarcinoma | Cytochrome c | Medical colleges | Chemotherapy | Membrane potentials | Fluorescein | Fluorescence | Mitochondrial DNA | Cancer | Chinese medicine | Acids | Cell cycle | Cytotoxicity | Experiments
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2006, Volume 14, Issue 16, pp. 5673 - 5677
Journal Article