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PloS one, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0175329 - e0175329
Teriparatide [human parathyroid hormone (1-34)], which exerts an anabolic effect on bone, is used for the treatment of osteoporosis in patients who are at a high risk for fracture... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Osteogenesis - physiology | X-Ray Microtomography | Bone and Bones - drug effects | Dose-Response Relationship, Drug | Collagen - drug effects | Bone and Bones - diagnostic imaging | Bone and Bones - metabolism | Biomechanical Phenomena - drug effects | Bone Resorption - metabolism | Female | Models, Animal | Bone Resorption - chemically induced | Porosity - drug effects | Imaging, Three-Dimensional | Bone and Bones - cytology | Rabbits | Bone Density Conservation Agents - adverse effects | Drug Administration Schedule | Teriparatide - administration & dosage | Teriparatide - blood | Osteogenesis - drug effects | Bone Density Conservation Agents - administration & dosage | Microscopy, Interference | Bone Density Conservation Agents - blood | Collagen - metabolism | Animals | Bone Resorption - pathology | Teriparatide - adverse effects | Microscopy, Fluorescence | Adaptations | Animal models | Spine | Bone (trabecular) | Bisphosphonates | Clinical outcomes | Bone resorption | Proteins | Osteoporosis | Alendronic acid | Bone growth | Computed tomography | Fibrous dysplasia | Bone marrow | Bone dysplasia | Tunneling | Skeleton | Bone density | Bone loss | Bone (cortical) | Drug therapy | Bone strength | Drug dosages | Age | Bone remodelling | Rats | Risk reduction | Endocrine therapy | Pharmacology | Frost | Bone turnover | Metabolism | Bone mass | Fractures | Osteodystrophy | Mice | Bone mineral density | Mutation | Porosity | Pharmacokinetics | Risk management | Kidney transplantation | Bone (cancellous) | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e92368 - e92368
.... Germ-free mice have increased bone mass associated with reduced bone resorption indicating that the GM also regulates bone mass. Ovariectomy (ovx... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Bone and Bones - pathology | Ovariectomy - adverse effects | T-Lymphocytes, Regulatory - metabolism | RANK Ligand - metabolism | Body Weight - drug effects | Bone and Bones - drug effects | Lactobacillus - drug effects | Bone Marrow - metabolism | Bone and Bones - metabolism | Inflammation Mediators - metabolism | Female | Minerals - metabolism | Bone Marrow - drug effects | Bone Resorption - etiology | Bone Resorption - blood | Cytokines - metabolism | Mice, Inbred C57BL | Bone Resorption - drug therapy | Biomarkers - blood | Probiotics - pharmacology | Lactobacillus - metabolism | Bone Resorption - prevention & control | Organ Size - drug effects | T-Lymphocytes, Regulatory - drug effects | Animals | Bone Marrow - pathology | Probiotics - therapeutic use | Mice | Osteoprotegerin - metabolism | Transforming Growth Factor beta - metabolism | Probiotics | Ovariectomy | Microbiota (Symbiotic organisms) | Physiological aspects | Bones | T cells | Density | Drinking water | Calcium | Lymphocytes T | Genomes | Arthritis | Immune status | Osteoprotegerin | Bone resorption | Osteoporosis | Microorganisms | Biomedical materials | Microbiota | Lymphocytes | Bone marrow | Bacteria | Tumor necrosis factor-TNF | Biocompatibility | Bone density | Bone loss | Bone (cortical) | Bone composition | Food | Immune system | Calcium (urinary) | Excretion | Gnotobiotics | Cytokines | Nutrition | Immunoregulation | Rheumatology | Inflammation | Tumor necrosis factor-α | IL-1β | Metabolism | Gene expression | Bone mineral content | Medicine | Serum levels | Osteoclastogenesis | Bone mass | Antibiotics | Womens health | Ligands | Index Medicus | Endokrinologi och diabetes | Endocrinology and Diabetes
Journal Article
Journal of bone and mineral research, ISSN 0884-0431, 10/2017, Volume 32, Issue 10, pp. 2010 - 2021
Journal Article
PloS one, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, pp. e0177416 - e0177416
To improve the safe use of allograft bone, decellularization techniques may be utilized to produce acellular scaffolds... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Proliferation | Age Factors | Humans | Middle Aged | Transcriptome | Culture Media, Conditioned - pharmacology | Male | Tissue Scaffolds | Cell Differentiation - genetics | Bone and Bones - diagnostic imaging | Bone and Bones - metabolism | Mesenchymal Stem Cells - cytology | Mesenchymal Stem Cells - drug effects | Aged, 80 and over | Adult | Female | Mesenchymal Stem Cells - metabolism | Osteogenesis - genetics | Bone Density | Bone Regeneration | Radiography | Cell Differentiation - drug effects | Bone Transplantation | Biomarkers | Aged | Tissue Donors | Culture Media, Conditioned - metabolism | Bones | Bone-grafting | Growth | Health aspects | Patient outcomes | Osseointegration | Health services | Carbon dioxide | Bone (trabecular) | Bone surgery | Blood | Proteins | Osteoporosis | Pore size | Bone growth | Surgery | Topography | Bone marrow | Aging | Bone (cortical) | Bone matrix | Bone composition | Autografts | Longevity | Bone healing | Bioavailability | Metabolism | Insulin | Chemicals | Studies | Immunogenicity | Quality control | Stem cells | Osteoarthritis | Endocrinology | Age composition | Bone (cancellous) | Adherent cells | Osteoprogenitor cells | Animal models | Calcium | Biology | Arthritis | Insulin-like growth factors | Engineering | Allografts | Rodents | Extracellular matrix | Bone loss | Age | Immune response | Bone morphogenetic protein 2 | Tissue engineering | Complications | Bioassays | Feasibility studies | Hip | Medicine | Skin & tissue grafts | Porosity | Bone morphogenetic protein 9 | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e95144 - e95144
Adult Ibsp-knockout mice (BSP-/-) display shorter stature, lower bone turnover and higher trabecular bone mass than wild type, the latter resulting from impaired bone resorption... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Osteopontin - blood | Osteopontin - genetics | Osteopontin - deficiency | Male | Insulin-Like Growth Factor I - genetics | Mice, 129 Strain | Growth Plate - growth & development | Behavior, Animal | Hedgehog Proteins - genetics | Bone Resorption - genetics | Gene Expression Regulation, Developmental | Female | Tibia - growth & development | Tibia - metabolism | Femur - growth & development | Osteogenesis - genetics | Animals, Newborn | Femur - metabolism | Growth Plate - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Osteoclasts - metabolism | Mice, Knockout | Animals | Bone Development - genetics | Osteoblasts - metabolism | Bones | Growth | Density | Analysis | Neonates | Femur | Insulin-like growth factor I | Bone sialoprotein | Insulin-like growth factors | Birth | Bone (trabecular) | Accumulation | Bone resorption | Cartilage | Genotype & phenotype | Reproductive behavior | Biomedical materials | Bone growth | Mineralization | Tibia | Rodents | Sutures | Biocompatibility | Bone (cortical) | Bone (endochondral) | Genotypes | Cbfa-1 protein | Heredity | Bone turnover | Gene expression | Mutants | Childbirth & labor | Bone mass | Hedgehog protein | Skull | Bone mineral density | Adults | Mice | Bone (long) | Osteogenesis | Index Medicus | Life Sciences
Journal Article
Bone, ISSN 8756-3282, 2016, Volume 93, pp. 86 - 96
Abstract Odanacatib (ODN) a selective and reversible cathepsin K inhibitor, inhibits bone resorption, increases bone mass and reduces fracture risk in women with osteoporosis. A 16-month... 
Orthopedics | Osteoporosis | Odanacatib | Bone remodeling | Alendronate | Bone strength | Cathepsin K inhibitor | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Bone and Bones - pathology | Femur - pathology | Tomography, X-Ray Computed | Cancellous Bone - drug effects | Cortical Bone - pathology | Femur - diagnostic imaging | Biphenyl Compounds - therapeutic use | Bone Remodeling - drug effects | Bone and Bones - drug effects | Bone Diseases, Metabolic - drug therapy | Cancellous Bone - diagnostic imaging | Biphenyl Compounds - pharmacology | Bone and Bones - diagnostic imaging | Cancellous Bone - pathology | Female | Lumbar Vertebrae - physiopathology | Disease Models, Animal | Biomarkers - metabolism | Rabbits | Cancellous Bone - physiopathology | Bone Diseases, Metabolic - diagnostic imaging | Ovariectomy | Cortical Bone - physiopathology | Lumbar Vertebrae - drug effects | Femur - physiopathology | Withholding Treatment | Absorptiometry, Photon | Regression Analysis | Biomechanical Phenomena | Bone Density - drug effects | Bone and Bones - physiopathology | Organ Size - drug effects | Animals | Lumbar Vertebrae - pathology | Bone Diseases, Metabolic - physiopathology | Cortical Bone - diagnostic imaging | Cathepsins | Aluminum compounds | Bones | Density | Analysis | Index Medicus
Journal Article
Osteoporosis international, ISSN 0937-941X, 3/2018, Volume 29, Issue 3, pp. 685 - 697
Abaloparatide, a novel PTH1 receptor agonist, increased bone formation in osteopenic ovariectomized cynomolgus monkeys while increasing cortical and trabecular bone mass... 
Osteoporosis | Abaloparatide | Medicine & Public Health | Orthopedics | Rheumatology | Bone quality | PTH1R | Bone strength | Endocrinology | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Bone Resorption - physiopathology | Osteogenesis - physiology | Bone Density - physiology | Ovariectomy | Osteogenesis - drug effects | Bone Density Conservation Agents - therapeutic use | Macaca fascicularis | Procollagen - blood | Biomarkers - blood | Receptor, Parathyroid Hormone, Type 1 - agonists | X-Ray Microtomography - methods | Bone Density Conservation Agents - pharmacology | Parathyroid Hormone-Related Protein - pharmacology | Parathyroid Hormone-Related Protein - therapeutic use | Bone Resorption - prevention & control | Bone Density - drug effects | Animals | Peptide Fragments - blood | Absorptiometry, Photon - methods | Female | Lumbar Vertebrae - physiopathology | Bone resorption | Bones | Care and treatment | Density | Analysis | Femur | Calcium | Bone (trabecular) | Diaphysis | Bone histomorphometry | Bone growth | Calcium (blood) | Vitamin D | Computed tomography | Surgery | Bone density | Densitometry | Bone (cortical) | Dual energy X-ray absorptiometry | Vertebrae | Bone turnover | Post-menopause | Bone mass | Parathyroid hormone | Porosity | Humerus | Osteogenesis | Index Medicus | Original
Journal Article
Journal of bone and mineral research, ISSN 0884-0431, 05/2017, Volume 32, Issue 5, pp. 1062 - 1071
Journal Article