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Nature Chemical Biology, ISSN 1552-4450, 02/2018, Volume 14, Issue 3, pp. 201 - 202
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2015, Volume 108, Issue 2, pp. 342a - 342a
Journal Article
NATURE, ISSN 0028-0836, 06/2011, Volume 474, Issue 7352, pp. 521 - U154
Adenosine receptors and beta-adrenoceptors are G-protein-coupled receptors (GPCRs) that activate intracellular G proteins on binding the agonists adenosine(1)... 
CRYSTALLIZATION | ADRENOCEPTOR | COMPLEX | ANTAGONIST | CRYSTAL-STRUCTURE | THERMOSTABILIZATION | STABILITY | MULTIDISCIPLINARY SCIENCES | RHODOPSIN | PROTEIN-COUPLED RECEPTORS | BINDING
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2017, Volume 174, Issue S1, pp. S272 - S359
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective... 
PHARMACOLOGY & PHARMACY | Enzymes | Pharmacology | G protein-coupled receptors | Nomenclature | Ion channels (ligand-gated) | Ligands | Ions | Ion channels | Nuclear receptors | Index Medicus | The Concise Guide to Pharmacology 2017
Journal Article
NATURE, ISSN 0028-0836, 04/2015, Volume 520, Issue 7547, pp. 317 - 317
In response to adenosine 59-diphosphate, the P2Y(1) receptor (P2Y(1)R) facilitates platelet aggregation, and thus serves as an important antithrombotic drug... 
COMPLEX | NUCLEOTIDE RECEPTORS | RECOGNITION | SMALL-MOLECULE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | PROTEIN-COUPLED RECEPTORS | PURINERGIC RECEPTORS | ANTAGONISTS | DISCOVERY | AGONIST
Journal Article
03/2012
A large number of G-protein-coupled receptors (GPCRs) show varying degrees of basal or constitutive activity. This constitutive activity is usually minimal in... 
Constitutive activity | inverse agonists | G-protein-coupled receptors | inverse agonism
Web Resource
Nature communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 554 - 1
The original version of this Article omitted a declaration from the Competing Interests statement, which should have included the following: 'J.D.B. is a... 
Engineering | G protein-coupled receptors | Human communication
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2017, Volume 174, Issue S1, pp. S360 - S446
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective... 
Pharmacology | G protein-coupled receptors | Nomenclature | Ion channels (ligand-gated) | Ligands | Ions | Ion channels | Nuclear receptors | Index Medicus | The Concise Guide to Pharmacology 2017
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2017, Volume 174, Issue S1, pp. S225 - S271
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective... 
PHARMACOLOGY & PHARMACY | Pharmacology | G protein-coupled receptors | Nomenclature | Ion channels (ligand-gated) | Ligands | Ions | Ion channels | Nuclear receptors | Index Medicus | The Concise Guide to Pharmacology 2017
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 08/2015, Volume 58, Issue 16, pp. 6653 - 6664
Fragment screening of a thermostabilized mGlu(5) receptor using a high-concentration radioligand binding assay enabled the identification of moderate affinity,... 
GLUTAMATE-RECEPTOR 5 | DEPRESSION | DESIGN | CHEMISTRY, MEDICINAL | SAR | CLINICAL DEVELOPMENT | PHARMACOLOGY | BASIMGLURANT | DOUBLE-BLIND | PROTEIN-COUPLED RECEPTORS | IDENTIFICATION
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2017, Volume 174, Issue S1, pp. S17 - S129
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective... 
HIGH-AFFINITY | PHARMACOLOGY & PHARMACY | POTENT | SERIES | ANTAGONISTS | AGONIST | Pharmacology | G proteins | G protein-coupled receptors | Nomenclature | Ion channels (ligand-gated) | Ligands | Ions | Ion channels | Nuclear receptors | Index Medicus | The Concise Guide to Pharmacology 2017
Journal Article