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Circulation: Arrhythmia and Electrophysiology, ISSN 1941-3149, 06/2015, Volume 8, Issue 3, pp. 633 - 642
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 03/2012, Volume 4, Issue 3, pp. 180 - 191
Coordinated release of calcium (Ca2+) from the sarcoplasmic reticulum (SR) through cardiac ryanodine receptor (RYR2) channels is essential for cardiomyocyte... 
ryanodine receptor 2 | dantrolene | induced pluripotent stem cells | CPVT | disease modelling | Disease modelling | Dantrolene | Ryanodine receptor 2 | Induced pluripotent stem cells | MEDICINE, RESEARCH & EXPERIMENTAL | MALIGNANT HYPERTHERMIA | POSTULATED ROLE | DOMAIN INTERACTIONS | CARDIAC RYANODINE RECEPTOR | LONG-QT SYNDROME | IN MOUSE MODEL | FAILING HEARTS | THERAPEUTIC AGENT | CA2+ CHANNEL REGULATION | CALCIUM-RELEASE | Induced Pluripotent Stem Cells - drug effects | Calcium - metabolism | Sarcoplasmic Reticulum - drug effects | Tachycardia, Ventricular - drug therapy | Humans | Cells, Cultured | Ryanodine Receptor Calcium Release Channel - metabolism | Dantrolene - pharmacology | Myocytes, Cardiac - drug effects | Ryanodine Receptor Calcium Release Channel - genetics | Models, Biological | Tachycardia, Ventricular - metabolism | Myocytes, Cardiac - metabolism | Tachycardia, Ventricular - genetics | Adult | Female | Ion Transport - drug effects | Sarcoplasmic Reticulum - metabolism | Induced Pluripotent Stem Cells - metabolism | Heart | Analysis | Central nervous system depressants | Stem cells | Ventricular tachycardia | Models | Calcium-binding proteins | Cardiac arrhythmia | Arrhythmia | Pathogenesis | Genes | Ryanodine receptors | Amino acids | Myocytes | Experiments | Calcium signalling | Sarcoplasmic reticulum | Fibroblasts | Age | Calsequestrin | Phenotypes | Cardiac muscle | Malignant hyperthermia | Mortality | Cardiomyocytes | Patients | Hereditary diseases | Tachycardia | Mutation | Ventricle | Hyperthermia | Pluripotency | Evacuations & rescues | Calcium (reticular) | Inhibitory postsynaptic potentials
Journal Article
Journal of Arrhythmia, ISSN 1880-4276, 2015, Volume 32, Issue 5, pp. 344 - 351
Abstract Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotions or exercise in patients without organic heart disease and may be... 
Cardiovascular | Ryanodine (RyR2) | Left cardiac sympathetic denervation | Catecholaminergic polymorphic ventricular tachycardia (CPVT) | Calsequestrine (CASQ2) | Delayed after depolarization | Ventricular tachycardia | Usage | Diagnosis | Gene mutations | Gene therapy | Analysis | Electrocardiography | Mutation | Kinases | Catheters | Review
Journal Article
Circulation Research, ISSN 0009-7330, 11/2007, Volume 101, Issue 10, pp. 1039 - 1048
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 08/2012, Volume 111, Issue 6, pp. 708 - 717
Journal Article
Journal of Cardiovascular Electrophysiology, ISSN 1045-3873, 10/2019, Volume 30, Issue 10, pp. 1923 - 1929
Introduction Risk stratification tools for catecholaminergic polymorphic ventricular tachycardia (CPVT) are limited. The exercise stress test (EST) is the most... 
ventricular arrhythmia | heart rate | chronotropic incompetence | CPVT | exercise stress test | Heart | Heart beat | Exercise | Cardiac patients | Anti-arrhythmia drugs | Ventricular tachycardia | Stress (Physiology) | Children | Health aspects | Cardiac arrhythmia | Therapy | Signs and symptoms | Young adults | Arrhythmia | Risk | Heart rate | Tachycardia | Syncope | Electrocardiography | Blood pressure | Diagnostic systems | Ventricle
Journal Article
Cell Death and Disease, ISSN 2041-4889, 10/2013, Volume 4, Issue 10, pp. e843 - e843
Induced pluripotent stem cells (iPSC) offer a unique opportunity for developmental studies, disease modeling and regenerative medicine approaches in humans.... 
Cardiomyocytes | Calcium/calmodulin pathway | CPVT | Diseases modeling | Induced pluripotent stem cells | ARRHYTHMOGENESIS | BETA-ADRENERGIC STIMULATION | DEFINED FACTORS | FLECAINIDE | INHERITED ARRHYTHMIAS | CELL BIOLOGY | cardiomyocytes | PLURIPOTENT STEM-CELLS | diseases modeling | RYANODINE RECEPTOR | MOUSE MODEL | induced pluripotent stem cells | DYSFUNCTION | calcium/calmodulin pathway | Tachycardia, Ventricular - enzymology | Calcium - metabolism | Humans | Child, Preschool | Molecular Sequence Data | Male | Arrhythmias, Cardiac - pathology | Base Sequence | HEK293 Cells | Adult | Female | Induced Pluripotent Stem Cells - cytology | Receptors, Adrenergic, beta - metabolism | Child | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Induced Pluripotent Stem Cells - metabolism | Tachycardia, Ventricular - complications | Induced Pluripotent Stem Cells - drug effects | Tachycardia, Ventricular - drug therapy | Sulfonamides - pharmacology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Myocytes, Cardiac - pathology | Arrhythmias, Cardiac - drug therapy | Phenotype | Animals | Myocytes, Cardiac - drug effects | Ryanodine Receptor Calcium Release Channel - genetics | Sulfonamides - therapeutic use | Cell Differentiation - drug effects | Pedigree | Protein Kinase Inhibitors - therapeutic use | Adolescent | Arrhythmias, Cardiac - enzymology | Myocytes, Cardiac - metabolism | Tachycardia, Ventricular - pathology | Arrhythmias, Cardiac - complications | Mice | Protein Kinase Inhibitors - pharmacology | Benzylamines - pharmacology | Benzylamines - therapeutic use | calcium | calmodulin pathway | Original
Journal Article
Circulation: Cardiovascular Genetics, ISSN 1942-325X, 10/2013, Volume 6, Issue 5, pp. 481 - 489
Journal Article