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JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 07/2019, Volume 203, Issue 1, pp. 6 - 10
Proteins binding the third component of complement (C3) were isolated by affinity chromatography from surface-labeled solubilized membranes of human peripheral... 
COMPLEMENT | C3B RECEPTOR | ANTICOMPLEMENTARY AGENT | POLYMORPHISM | IMMUNOLOGY | MACROPHAGE RECEPTOR | C3B/C4B RECEPTOR | CR-1 | HUMAN-ERYTHROCYTE | HUMAN-MONOCYTES | LYMPHOCYTES
Journal Article
by Hollingworth, P and Harold, D and Sims, R and Gerrish, A and Lambert, J.C and Carrasquillo, M.M and Abraham, R and Hamshere, M.L and Pahwa, J.S and Moskvina, V and Dowzell, K and Jones, N and Stretton, A and Thomas, C and Richards, A and Ivanov, D and Widdowson, C and Chapman, J and Lovestone, S and Powell, J and Proitsi, P and Lupton, M.K and Brayne, C and Rubinsztein, D.C and Gill, M and Lawlor, B and Lynch, A and Brown, K.S and Passmore, P.A and Craig, D and McGuinness, B and Todd, S and Holmes, C and Mann, D and Smith, A.D and Beaumont, H and Warden, D and Wilcock, G and Love, S and Kehoe, P.G and Hooper, N.M and Vardy, E.R.L.C and Hardy, J and Mead, S and Fox, N.C and Rossor, M and Collinge, J and Maier, W and Jessen, F and Ruther, E and Schurmann, B and Heun, R and Kolsch, H and van den Bussche, H and Heuser, I and Kornhuber, J and Wiltfang, J and Dichgans, M and Frolich, L and Hampel, H and Gallacher, J and Hull, M and Rujescu, D and Giegling, I and Goate, A.M and Kauwe, J.S.K and Cruchaga, C and Nowotny, P and Morris, J.C and Mayo, K and Sleegers, K and Bettens, K and Engelborghs, S and de Deyn, P.P and Van Broeckhoven, C and Livingston, G and Bass, N.J and Gurling, H and McQuillin, A and Gwilliam, R and Deloukas, P and Al-Chalabi, A and Shaw, C.E and Tsolaki, M and Singleton, A.B and Guerreiro, R and Muhleisen, T. W and Nothen, M. M and Moebus, S and Jockel, K.H and Klopp, N and Wichmann, H. E and Pankratz, V.S and Sando, S.B and Aasly, J.O and Barcikowska, M and Wszolek, Z.K and Dickson, D.W and Graff-Radford, N.R. and others and Alzheimer's Dis Neuroimaging and EADI1 Consortium and CHARGE Consortium and Alzheimer's Disease Neuroimaging Initiative and EADI1 consortium and CHARGE consortium and the Alzheimer's Disease Neuroimaging Initiative
Nature Genetics, ISSN 1061-4036, 2011, Volume 43, Issue 5, pp. 429 - 435
Journal Article
by Han, ZJ and Qu, JJ and Zhao, JH and Zou, X
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2018, Volume 8, Issue 1, pp. 11062 - 11062
Clusterin (CLU) is considered one of the most important roles for pathogenesis of Alzheimer's Disease (AD). The early genome-wide association studies (GWAS)... 
IDENTIFIES VARIANTS | GENOTYPE | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | PICALM POLYMORPHISMS | CLUSTERIN | RISK SCORE | CR-1 | MEDICINE | GENE POLYMORPHISMS | GENOME-WIDE ASSOCIATION
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2011, Volume 108, Issue 32, pp. 13236 - 13240
Activation of C3, deposition of C3b on the target surface, and subsequent amplification by formation of a C3-cleaving enzyme (C3-convertase; C3bBb) triggers... 
PROVIDES INSIGHTS | CONVERTASE FORMATION | ACTIVATION | CONFORMATIONAL-CHANGES | FACTOR-B | MULTIDISCIPLINARY SCIENCES | RECEPTOR | FACTOR-H | FACTOR-I | CR-1 | COMPLEMENT COMPONENT C3
Journal Article
JOURNAL OF ALZHEIMERS DISEASE, ISSN 1387-2877, 2019, Volume 69, Issue 1, pp. 37 - 48
It is an open issue whether blood biomarkers serve to diagnose Alzheimer's disease (AD) or monitor its progression over time from prodromal stages. Here, we... 
clinical trial | clusterin | biomarkers | Amnesic mild cognitive impairment | RISK | CR-1 | amyloid-beta peptide | CLU | NEUROSCIENCES | prodromal Alzheimer's disease | CSF | ASSOCIATION | PharmaCog project
Journal Article
Annals of Neurology, ISSN 0364-5134, 03/2018, Volume 83, Issue 3, pp. 544 - 552
Journal Article
Nature, ISSN 0028-0836, 2006, Volume 444, Issue 7116, pp. 213 - 216
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 07/2019, Volume 129, pp. 162 - 168
Treatment of many inflammatory diseases involves a chronic use of NSAIDs in large doses increasing acute kidney injury risk. This study was designed to... 
MCP-1 | Nephropathy | CR-1 | Caspase-3 | Gum acacia | Diclofenac | FIBROSIS | ACTIVATION | SENEGAL | FOOD SCIENCE & TECHNOLOGY | INJURY | REGULATORY PROTEINS | EPITHELIAL-CELLS | RENAL-FAILURE | TOXICOLOGY | TISSUES | KIDNEY | EXPRESSION | Antioxidants | Interleukins | Pharmacy | Drugstores | Kidney diseases | Nonsteroidal anti-inflammatory drugs | Apoptosis
Journal Article
by Varatharajah, Yogatheesan and Ramanan, Vijay K and Iyer, Ravishankar and Vemuri, Prashanthi and Weiner, Michael W and Aisen, Paul and Petersen, Ronald and Jack, Clifford R and Saykin, Andrew J and Jagust, William and Trojanowki, John Q and Toga, Arthur W and Beckett, Laurel and Green, Robert C and Morris, John and Shaw, Leslie M and Khachaturian, Zaven and Sorensen, Greg and Carrillo, Maria and Kuller, Lew and Raichle, Marc and Paul, Steven and Davies, Peter and Fillit, Howard and Hefti, Franz and Holtzman, David and Mesulam, M. Marcel and Potter, William and Snyder, Peter and Schwartz, Adam and Montine, Tom and Thomas, Ronald G and Donohue, Michael and Walter, Sarah and Gessert, Devon and Sather, Tamie and Jiminez, Gus and Balasubramanian, Archana B and Mason, Jennifer and Sim, Iris and Harvey, Danielle and Bernstein, Matthew and Fox, Nick and Thompson, Paul and Schuff, Norbert and DeCArli, Charles and Borowski, Bret and Gunter, Jeff and Senjem, Matt and Jones, David and Kantarci, Kejal and Ward, Chad and Koeppe, Robert A and Foster, Norm and Reiman, Eric M and Chen, Kewei and Mathis, Chet and Landau, Susan and Cairns, Nigel J and Franklin, Erin and Taylor-Reinwald, Lisa and Lee, Virginia and Korecka, Magdalena and Figurski, Michal and Crawford, Karen and Neu, Scott and Foroud, Tatiana M and Potkin, Steven and Faber, Kelley and Kim, Sungeun and Nho, Kwangsik and Thal, Leon and Buckholtz, Neil and Albert, Marilyn and Frank, Richard and Hsiao, John and Kaye, Jeffrey and Quinn, Joseph and Silbert, Lisa and Lind, Betty and Carter, Raina and Dolen, Sara and Schneider, Lon S and Pawluczyk, Sonia and Beccera, Mauricio and Teodoro, Liberty and Spann, Bryan M and Brewer, James and Vanderswag, Helen and Fleisher, Adam and Heidebrink, Judith L and Lord, Joanne L and Mason, Sara S and Albers, Colleen S and Knopman, David and Johnson, Kris and Doody, Rachelle S and Villanueva-Meyer, Javier and Pavlik, Valory and Shibley, Victoria and ... and Alzheimers Dis Neuroimaging Initia and Alzheimer’s Disease Neuroimaging Initiative and For the Alzheimer’s Disease Neuroimaging Initiative
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 2235 - 15
In the Alzheimer's disease (AD) continuum, the prodromal state of mild cognitive impairment (MCI) precedes AD dementia and identifying MCI individuals at risk... 
MICROGLIAL ACTIVATION | F-18-FLORBETAPIR PET | DEMENTIA | VARIANTS | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | CR-1 | ASSOCIATION | CLU | IMPAIRMENT | DECLINE | Neuroimaging | Complement receptors | Learning algorithms | Demography | Tau protein | Cognitive ability | Dementia disorders | Amyloid | Genetic factors | Cerebrospinal fluid | Alzheimer's disease
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 02/2007, Volume 104, Issue 8, pp. 2767 - 2772
We report results of a megabase-scale phylogenomic analysis of the Reptilia, the sister group of mammals. Large-scale end-sequence scanning of genomic clones... 
retroelement | BAC | MITOCHONDRIAL | MULTIDISCIPLINARY SCIENCES | SIZE | AVIAN GENOME | EVOLUTIONARY DYNAMICS | CR-1 | isochore | MOLECULAR PHYLOGENY | VERTEBRATE EVOLUTION | intron | TURTLES | SEQUENCE | MICROSATELLITES | Reptilia
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 40, pp. 17327 - 17332
Journal Article