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Journal Article
2003, ISBN 9780080441986, xxviii, 1171
The International Handbook on Innovation is the most comprehensive and authoritative account available of what innovation is, how it is measured, how it is... 
Technological innovations | Creative ability | Social aspects | Creative thinking | Creative ability in business | Interdisciplinary studies
Book
The FEBS Journal, ISSN 1742-464X, 10/2017, Volume 284, Issue 19, pp. 3262 - 3277
The rat is an important laboratory animal for physiological, toxicological and pharmacological studies. Clustered regularly interspaced short palindromic... 
Rosa26 | CRISPR | Cre reporter | rat | Cre | loxP | Cas9 | CRISPR/Cas9 | Cre–loxP | RECOMBINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | WOLFRAM-SYNDROME | MOUSE | Cre-loxP | ESTROGEN-RECEPTOR | GENE | EMBRYONIC STEM-CELLS | MOUTH-DISEASE VIRUS | MICE | EXPRESSION | KNOCKOUT RATS | Dependovirus - genetics | RNA, Guide - genetics | RNA, Untranslated - metabolism | Embryo, Mammalian | RNA, Guide - metabolism | Male | Green Fluorescent Proteins - genetics | Genetic Loci | RNA, Untranslated - genetics | Myocardium - metabolism | Female | Integrases - metabolism | Genes, Reporter | Gene Targeting | Green Fluorescent Proteins - metabolism | Dependovirus - metabolism | Genetic Vectors - chemistry | Rats, Transgenic | Liver - metabolism | Gene Expression Regulation | Genetic Vectors - metabolism | Rats | Gene Knock-In Techniques | Animals | CRISPR-Cas Systems | Luminescent Proteins - genetics | Gene Editing - methods | Integrases - genetics | Crosses, Genetic | Luminescent Proteins - metabolism | Muscles | Genetic engineering | Journalists | Genetically modified organisms | Liver | Genetic resources | Transgenic | Trinucleotide repeats | Viruses | Pharmacology | Recombinase | Gene expression | Promoters | Cre recombinase | Skeletal muscle | Major histocompatibility complex | Rodents | In vivo methods and tests | Laboratory animals | Index Medicus
Journal Article
KLIMIK Dergisi, ISSN 1301-143X, 04/2018, Volume 31, Issue 1, p. 50
Amaç: Bu çalışmada, karbapeneme dirençli enterik bakteri (KDE)’lerin direnç özelliklerinin belirlenmesi ve ileriye yönelik alternatif tedavi seçeneklerinin... 
CRE bacteria
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 68, Issue 100, pp. 66 - 77
Abstract Rett syndrome (RTT) is a rare neurodevelopmental disorder affecting almost exclusively females, caused in the overwhelming majority of the cases by... 
Neurology | Lipid peroxidation | Oxidative stress | Brain damage | Neurodevelopmental disorder | Murine models | Rett syndrome | IRON | CPG-BINDING PROTEIN-2 | NEUROSCIENCES | CHOLESTEROL-METABOLISM | MECP2 MUTANT MICE | MOUSE MODEL | DISEASE | ANIMAL-MODELS | DISORDER | DYSFUNCTION | STRESS | Arachidonic Acid - metabolism | Rett Syndrome - complications | Gas Chromatography-Mass Spectrometry | Mice, Inbred C57BL | Neuroprostanes - metabolism | Oxidative Stress - physiology | Male | Mice, Transgenic | Aldehydes - metabolism | Mutation - genetics | Methyl-CpG-Binding Protein 2 - genetics | Animals | Isoprostanes - metabolism | Analysis of Variance | Nestin - genetics | Brain Injuries - blood | Female | Mice | Brain Injuries - etiology | Rett Syndrome - blood | Rett Syndrome - genetics | Brain Injuries - pathology | Disease Models, Animal | Docosahexaenoic Acids - metabolism | Models | Analysis | Protein binding | Index Medicus | Organic chemistry | Chemical Sciences | OS, oxidative stress | Mecp2 | y, hemizygous null mice | NPBI, non-protein-bound iron | Mecp2, methyl-CpG-binding protein 2 — mouse protein | CRE, Cre-Recombinase | AdA, adrenic acid | AUs, arbitrary units | ARA, arachidonic acid | 4-HNE PAs, 4-HNE protein adducts | PSV, Preserved Speech Variant | Mecp2, methyl-CpG-binding protein 2 — mouse gene | wt, wild type | wt-Cre, wild type expressing Cre recombinase | MECP2, methyl-CpG-binding protein 2 — human gene | y, symptomatic Mecp2 308-mutated hemizygous males | ROS, reactive oxygen species | F2-IsoPs, F2-isoprostanes | MeCP2, methyl-CpG-binding protein 2 — human protein | y, Lox | F2-dihomo-IsoPs, F2-dihomo-isoprostanes | 4-HNE PAs, 4-hydroxy-2-nonenal protein adducts | Mecp2 stop | y NestinCre, rescued Lox | ASDs, autism spectrum disorders | F4-NeuroPs, F4-neuroprostanes | Mecp2 308 | stop pre-symptomatic hemizygous mice | x, symptomatic Mecp2 308-mutated females | DHA, docosahexaenoic acid | PUFAs, polyunsaturated fatty acids | BDNF, brain-derived neurotrophic factor | IsoPs, isoprostanes | RTT, Rett syndrome | stop mice (Mecp2 reactivated in the nervous tissue) | 4-HNE, 4-hydroxy-2-nonenal
Journal Article
Diagnostic Microbiology and Infectious Disease, ISSN 0732-8893, 06/2019
Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of... 
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 11/2017, Volume 8, pp. 1618 - 1618
Conditional and inducible Cre-loxP systems are used to target gene deletion to specific cell lineages and tissues through promoter-restricted expression of the... 
CD68-rtTA | Csf1r-Cre | Lung | Cre | CX3CR1-estrogen receptor-Cre | Conditional | LysM-Cre | Macrophage | RECRUITED MACROPHAGES | conditional | LYMPH-NODES | macrophage | IMMUNOLOGY | MAMMALIAN-CELLS | lung | MURINE LUNG | PROTECTIVE ROLE | GENE-EXPRESSION | ALVEOLAR MACROPHAGES | TISSUE MACROPHAGES | STEADY-STATE | MONONUCLEAR PHAGOCYTES | Genetic engineering | Promoters (Genetics) | Macrophages | Properties | Health aspects | Methods
Journal Article
Frontiers in Cellular Neuroscience, ISSN 1662-5102, 03/2013, Volume 7, pp. 26 - 26
Microglial cells in brain and spinal cord are characterized by high expression of the chemokine receptor CX3CR1. Expression of the sole CX3CR1 ligand, the... 
Cre-loxP knock-in mice | CR1 | Neuroimmunology | Neuropathology | Microglia | Spinal cord | Neurons | Homeostasis | Parenchyma | CX3CR1 protein | Gene expression | Proteins | Brain research | Pain | Microscopy | Microglial cells | Ligands | Fractalkine | Localization | Chemokines | CX3CR1 | neuroimmunology | Cre-loxP knok-In mice
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 2019
Objective: Intimal hyperplasia (IH) is the main cause of therapeutic failure after vascular and endovascular surgery. However, there is currently no targeted... 
Decoy | Gene therapy | Intimal hyperplasia | CRE
Journal Article
JOURNAL OF IMMUNOLOGICAL METHODS, ISSN 0022-1759, 09/2016, Volume 436, pp. 54 - 57
The B6.Cg-Tg(Cd1-cre)1Cwi line expresses CRE recombinase under the control of the promoter and regulatory elements of the Cd4 gene. Here we show that CRE... 
CRE toxicity | CELLS | CRE recombinase | Genotyping | GENE | Whole genome sequencing | Transgene localisation | BIOCHEMICAL RESEARCH METHODS | SITES | IMMUNOLOGY | CD4 cre | MAMMALIAN GENOMES
Journal Article