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Journal of Cellular Physiology, ISSN 0021-9541, 09/2019, Volume 234, Issue 9, pp. 14422 - 14431
Cre/loxP technology is an important tool for studying cell type‐specific gene functions. Cre recombinase mouse lines, including Agc1‐CreERT2, Col2a1‐Cre;... 
intervertebral disc | annulus fibrosus | nucleus pulposus | Cre recombinase
Journal Article
PLoS Genetics, 11/2013, Volume 9, Issue 11
Oct4 is a widely recognized pluripotency factor as it maintains Embryonic Stem (ES) cells in a pluripotent state, and, in vivo, prevents the inner cell mass... 
Cre recombinase
Journal Article
Chembiochem : a European journal of chemical biology, ISSN 1439-4227, 6/2018, Volume 19, Issue 12, pp. 1239 - 1243
Optical control over protein expression could provide a means to interrogate a range of biological processes. One approach has employed caged ligands of the... 
Cyanine | Near-IR | Gene expression | Caging | Cre-Recombinase
Journal Article
PLoS ONE, 04/2013, Volume 8, Issue 4
The study of axis extension and somitogenesis has been greatly advanced through the use of genetic tools such as the TCre mouse line. In this line, Cre is... 
Cre recombinase
Journal Article
DIABETES, ISSN 0012-1797, 11/2015, Volume 64, Issue 11, pp. 3798 - 3807
There is growing concern over confounding artifacts associated with beta-cell-specific Cre-recombinase transgenic models, raising questions about their general... 
5-HYDROXYTRYPTAMINE RELEASE | POTENTIATION | INSULIN-SECRETION | MOUSE | ENDOCRINOLOGY & METABOLISM | PANCREATIC BETA-CELL | GENERATION | KNOCKOUT | MODEL | PROMOTER | CRE-RECOMBINASE
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 09/2019, Volume 234, Issue 9, pp. 14422 - 14431
Cre/loxP technology is an important tool for studying cell type-specific gene functions. Cre recombinase mouse lines, including Agc1-CreER.sup.T2, Col2a1-Cre;... 
Tamoxifen | Analysis | Recombination | Hedgehog protein | Fluorescence | Homeostasis | Bones | Recombinase | Nucleus pulposus | Tissues | Intervertebral discs | Cre recombinase
Journal Article
Nature Neuroscience, ISSN 1097-6256, 01/2012, Volume 15, Issue 1, pp. 163 - 170
Recent advances in optogenetics have improved the precision with which defined circuit elements can be controlled optically in freely moving mammals; in... 
HIPPOCAMPUS | RECORDINGS | CORTEX | IN-VIVO | LIGHT | CRE RECOMBINASE | NEURONS | POPULATIONS | NEURAL CIRCUITRY | NEUROSCIENCES | TRANSGENIC MICE | Genetic Techniques - instrumentation | Mice | Animals | Equipment Design | Neuroimaging | Electrophysiology | Neural circuitry | Research | Analysis | Methods
Journal Article
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 12/2018, Volume 59, Issue 6, pp. 706 - 712
Journal Article
Molecular and cellular biology, ISSN 0270-7306, 12/2018, Volume 38, Issue 23
Deficiency of huntingtin-interacting protein 1 (Hip1) results in degenerative phenotypes. Here we generated a deficiency allele where a floxed transcriptional... 
HIP1 | phosphocholine | kypholordosis | endocytosis | GDPD3 | Cre recombinase | GDE7
Journal Article
Developmental Dynamics, ISSN 1058-8388, 11/2015, Volume 244, Issue 11, pp. 1394 - 1403
Background: Neural crest cells play an important role in craniofacial morphogenesis and many other developmental processes. The formation of neural crest cells... 
craniofacial development | lineage tracing | neural crest | Cre recombinase | Craniofacial development | Lineage tracing | Neural crest | Genetic engineering
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 1 - 8
The Cre/loxP recombination system has revolutionized the ability to genetically manipulate animal genomes in order to conditionally control gene expression.... 
MULTIDISCIPLINARY SCIENCES | LACZ | Recombination | Genomes | Recombinase | Gene expression | Rodents | Cre recombinase
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 03/2002, Volume 90, Issue 4, pp. 458 - 464
Integrins link the extracellular matrix to the cellular cytoskeleton and serve important roles in cell growth, differentiation, migration, and survival.... 
Heart | Extracellular matrix | Positron emission tomography | Homologous recombination | Cre recombinase
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8
The BRAF(V600E) mutation is the most prevalent driver mutation of sporadic papillary thyroid cancers (PTC). It was previously shown that prenatal or postnatal... 
INITIATION | MULTIDISCIPLINARY SCIENCES | CRE RECOMBINASE | MOLECULAR PATHOGENESIS | BRAF | SENESCENCE | MICE | EXPRESSION | CARCINOMA | PROGRESSION | PTEN/MMAC1
Journal Article
eLife, ISSN 2050-084X, 11/2015, Volume 4, Issue 2015
Dopamine is released in the striatum during development and impacts the activity of Protein Kinase A (PKA) in striatal spiny projection neurons (SPNs). We... 
PATHWAYS | BIOLOGY | GENE-EXPRESSION | CRE RECOMBINASE | DARPP-32 | SEROTONIN | DOPAMINE-RECEPTORS
Journal Article