X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1335) 1335
biochemistry & molecular biology (1314) 1314
animals (1220) 1220
creb-binding protein (946) 946
index medicus (767) 767
mice (610) 610
cell biology (594) 594
nuclear proteins - metabolism (567) 567
creb-binding protein - metabolism (549) 549
protein binding (535) 535
trans-activators - metabolism (503) 503
creb-binding-protein (461) 461
transcriptional activation (440) 440
transcription factors - metabolism (435) 435
cell line (400) 400
acetylation (375) 375
phosphorylation (367) 367
transcription, genetic (365) 365
cbp (321) 321
gene-expression (310) 310
protein structure, tertiary (299) 299
molecular sequence data (294) 294
promoter regions, genetic (289) 289
proteins (266) 266
binding sites (262) 262
transfection (261) 261
amino acid sequence (260) 260
activation (252) 252
creb-binding protein - genetics (251) 251
nuclear proteins - genetics (249) 249
dna-binding proteins - metabolism (247) 247
signal transduction (246) 246
transcription (246) 246
trans-activators - genetics (237) 237
male (236) 236
histone acetyltransferases (228) 228
rats (227) 227
gene expression (224) 224
gene expression regulation (224) 224
transcription factors - genetics (216) 216
mutation (214) 214
p300 (213) 213
cells, cultured (212) 212
article (204) 204
histones - metabolism (195) 195
research (194) 194
hela cells (192) 192
expression (190) 190
transcription factors (186) 186
genetics & heredity (173) 173
dna-binding (166) 166
histone acetyltransferase (165) 165
cell line, tumor (160) 160
biophysics (159) 159
nf-kappa-b (159) 159
base sequence (156) 156
transcriptional regulation (155) 155
acetyltransferases - metabolism (152) 152
female (151) 151
cyclic amp response element-binding protein - metabolism (148) 148
cell nucleus - metabolism (144) 144
creb (143) 143
chromatin (141) 141
in-vivo (140) 140
nuclear proteins - chemistry (139) 139
neurosciences (138) 138
recombinant fusion proteins - metabolism (137) 137
trans-activators - chemistry (137) 137
coactivator (129) 129
gene (129) 129
creb-binding protein - chemistry (128) 128
dna-binding proteins - genetics (127) 127
oncology (126) 126
rna-polymerase-ii (123) 123
analysis (121) 121
apoptosis (120) 120
models, molecular (120) 120
multidisciplinary sciences (119) 119
genes, reporter (118) 118
blotting, western (110) 110
creb binding-protein (108) 108
genetic aspects (107) 107
cos cells (106) 106
transcription factor (105) 105
transcription factors - chemistry (105) 105
cancer (102) 102
trans-activators - physiology (102) 102
genes (101) 101
chromatin - metabolism (99) 99
biology (98) 98
nuclear proteins - physiology (98) 98
tumor cells, cultured (97) 97
biochemistry (95) 95
complex (95) 95
dna - metabolism (94) 94
physiological aspects (94) 94
binding (91) 91
models, biological (91) 91
research article (91) 91
ligands (90) 90
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Biological Chemistry, ISSN 0021-9258, 03/2016, Volume 291, Issue 13, pp. 6714 - 6722
The transcriptional coactivators CREB-binding protein (CBP) and p300 undergo a particularly rich set of interactions with disordered and partly ordered... 
ACTIVATION DOMAIN | UNSTRUCTURED PROTEINS | viral oncoprotein | intrinsically disordered protein | coupled folding and binding | intrinsically disordered region | BIOCHEMISTRY & MOLECULAR BIOLOGY | structure-function | STAT transcription factor | C-MYB | transcriptional coactivator | VIRAL-PROTEINS | transcriptional activation | P53 TRANSACTIVATION DOMAIN | COMPLEX-FORMATION | cAMP response element-binding protein (CREB) | hypoxia-inducible factor (HIF) | IDP | STRUCTURAL BASIS | IDR | KIX DOMAIN | TAZ2 DOMAIN | PEPTIDE MOTIFS | protein-protein interaction | Humans | E1A-Associated p300 Protein - genetics | STAT Transcription Factors - metabolism | CREB-Binding Protein - chemistry | NF-kappa B - metabolism | E1A-Associated p300 Protein - metabolism | NF-kappa B - chemistry | Viral Proteins - metabolism | Tumor Suppressor Protein p53 - genetics | CREB-Binding Protein - genetics | CREB-Binding Protein - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - chemistry | Transcription, Genetic | Protein Interaction Domains and Motifs | Protein Structure, Secondary | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Viral Proteins - chemistry | E1A-Associated p300 Protein - chemistry | Tumor Suppressor Protein p53 - metabolism | Models, Molecular | Viral Proteins - genetics | Intrinsically Disordered Proteins - genetics | Protein Folding | STAT Transcription Factors - genetics | NF-kappa B - genetics | Intrinsically Disordered Proteins - chemistry | Protein Binding | STAT Transcription Factors - chemistry | Tumor Suppressor Protein p53 - chemistry | Intrinsically Disordered Proteins - metabolism | Minireviews
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7337, pp. 189 - 196
B-cell non-Hodgkin's lymphoma comprises biologically and clinically distinct diseases the pathogenesis of which is associated with genetic lesions affecting... 
CBP | RUBINSTEIN-TAYBI SYNDROME | HISTONE ACETYLTRANSFERASES | ACETYLATION | P300 | MULTIDISCIPLINARY SCIENCES | CREB-BINDING-PROTEIN | CYCLE ARREST | ACUTE MYELOID-LEUKEMIA | TRANSCRIPTIONAL COACTIVATOR | P53 | Histone Acetyltransferases - deficiency | Recurrence | Acetyltransferases - metabolism | Histone Acetyltransferases - chemistry | Humans | E1A-Associated p300 Protein - genetics | Gene Expression Regulation, Neoplastic | Histone Acetyltransferases - genetics | CREB-Binding Protein - chemistry | E1A-Associated p300 Protein - metabolism | Lymphoma, B-Cell - genetics | Acetyltransferases - genetics | Mutation, Missense - genetics | CREB-Binding Protein - genetics | DNA-Binding Proteins - metabolism | CREB-Binding Protein - metabolism | Lymphoma, Follicular - genetics | Acetyltransferases - deficiency | Base Sequence | Histone Acetyltransferases - metabolism | Lymphoma, B-Cell - enzymology | HEK293 Cells | Acetylation | CREB-Binding Protein - deficiency | Lymphoma, Large B-Cell, Diffuse - pathology | Lymphoma, Follicular - pathology | Cells, Cultured | E1A-Associated p300 Protein - chemistry | Lymphoma, Large B-Cell, Diffuse - enzymology | Tumor Suppressor Protein p53 - metabolism | Protein Structure, Tertiary - genetics | Mutation - genetics | Acetyl Coenzyme A - metabolism | Acetyltransferases - chemistry | Animals | Lymphoma, B-Cell - pathology | Polymorphism, Single Nucleotide - genetics | Protein Binding | Lymphoma, Follicular - enzymology | Mice | E1A-Associated p300 Protein - deficiency | Lymphoma, Large B-Cell, Diffuse - genetics | Proto-Oncogene Proteins c-bcl-6 | Sequence Deletion - genetics | Lymphomas | Genetic aspects | B cells | Gene mutations | Health aspects | Abnormalities | Proteins | Congenital diseases | Pathogenesis | Genes | Cell cycle | Genomes | Genetic engineering | Mutation | Binding sites
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2016, Volume 291, Issue 13, pp. 6689 - 6695
Intrinsically disordered proteins (IDPs) are characterized by a lack of persistent structure. Since their identification more than a decade ago, many questions... 
signaling | residual structure | electrostatics | coupled folding and binding | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein electrostatics | C-MYB | TRANSITION-STATE | INDUCED FIT | protein-protein interactions | INTRINSICALLY DISORDERED PROTEINS | LINEAGE LEUKEMIA PROTEIN | IDP | MOLECULAR RECOGNITION | KIX DOMAIN | SEQUENCE | protein folding | phi-value | TRANSACTIVATION DOMAIN | kinetics | biophysics | protein dynamic | CONFORMATIONAL SELECTION | Cyclic AMP Response Element-Binding Protein - chemistry | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | CREB-Binding Protein - chemistry | Proto-Oncogene Proteins - chemistry | CREB-Binding Protein - genetics | CREB-Binding Protein - metabolism | Thermodynamics | Apoptosis Regulatory Proteins - genetics | Myeloid Cell Leukemia Sequence 1 Protein - chemistry | Protein Interaction Domains and Motifs | Proto-Oncogene Proteins - metabolism | Signal Transduction | Apoptosis Regulatory Proteins - chemistry | Proto-Oncogene Proteins - genetics | Static Electricity | Intrinsically Disordered Proteins - genetics | Molecular Dynamics Simulation | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Protein Folding | Apoptosis Regulatory Proteins - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Intrinsically Disordered Proteins - chemistry | Cyclic AMP Response Element-Binding Protein - metabolism | Hydrophobic and Hydrophilic Interactions | Protein Binding | Kinetics | Intrinsically Disordered Proteins - metabolism | Minireviews
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2014, Volume 136, Issue 26, pp. 9308 - 9319
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 11/2016, Volume 17, Issue 11, pp. 1874 - 1874
Journal Article
Journal Article
Science, ISSN 0036-8075, 4/2009, Volume 324, Issue 5924, pp. 213 - 215
Structure-based drug design traditionally uses static protein models as inspirations for focusing on "active" site targets. Allosteric regulation of biological... 
Proteins | Molecules | Enzymes | Perspective | Allosteric regulation | Active sites | Drug interactions | Macromolecules | Medical treatment | Ligands | Drug design | ALLOSTERIC REGULATION | BINDING MODES | IN-VITRO | HIGH-AFFINITY LIGANDS | MECHANISM | NMR-SPECTROSCOPY | MULTIDISCIPLINARY SCIENCES | DYNAMICS | PROTEIN-PROTEIN INTERACTIONS | INHIBITORS | ANTAGONISTS | Apoproteins - chemistry | Cyclic AMP Response Element-Binding Protein - chemistry | Allosteric Regulation | Protein Multimerization | CREB-Binding Protein - chemistry | Piperazines - metabolism | Proto-Oncogene Proteins c-mdm2 - chemistry | Pyrimidines - metabolism | CREB-Binding Protein - metabolism | Thermodynamics | Enzyme Inhibitors - chemistry | Drug Design | Nuclear Magnetic Resonance, Biomolecular | Proto-Oncogene Proteins c-mdm2 - metabolism | Apoproteins - metabolism | Catalytic Domain | Signal Transduction | Enzyme Inhibitors - pharmacology | Tumor Suppressor Protein p53 - metabolism | Pyrimidines - pharmacology | Drug Discovery | Imatinib Mesylate | Piperazines - pharmacology | Proteins - metabolism | Small Molecule Libraries | Allosteric Site | Cyclic AMP Response Element-Binding Protein - metabolism | Protein Binding | Protein Conformation | Tumor Suppressor Protein p53 - chemistry | Benzamides | Proteins - chemistry | Proteins - antagonists & inhibitors | Protein-Tyrosine Kinases - antagonists & inhibitors | Drug delivery devices | Evaluation | Molecular dynamics | Nuclear magnetic resonance spectroscopy | Design and construction | Research | Structure | Methods | Pharmacology | Biomedical research | Molecular biology | Binding sites
Journal Article