X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (541) 541
cremophor el (467) 467
pharmacology & pharmacy (360) 360
humans (336) 336
paclitaxel (292) 292
animals (289) 289
cremophor-el (258) 258
oncology (201) 201
female (192) 192
male (184) 184
mice (160) 160
paclitaxel - administration & dosage (158) 158
pharmacokinetics (158) 158
taxol (148) 148
paclitaxel - pharmacokinetics (130) 130
cancer (124) 124
glycerol - analogs & derivatives (119) 119
rats (113) 113
in-vitro (104) 104
antineoplastic agents, phytogenic - administration & dosage (102) 102
antineoplastic agents, phytogenic - pharmacokinetics (89) 89
drug delivery systems (88) 88
p-glycoprotein (86) 86
nanoparticles (84) 84
middle aged (83) 83
paclitaxel - chemistry (83) 83
adult (77) 77
solubility (76) 76
chemotherapy (74) 74
micelles (74) 74
chemistry, multidisciplinary (72) 72
aged (66) 66
formulation (65) 65
neoplasms - drug therapy (65) 65
paclitaxel - pharmacology (64) 64
particle size (64) 64
tissue distribution (64) 64
cell line, tumor (63) 63
dose-response relationship, drug (63) 63
administration, oral (61) 61
nonlinear pharmacokinetics (61) 61
multidrug-resistance (60) 60
paclitaxel - therapeutic use (60) 60
paclitaxel - adverse effects (59) 59
area under curve (57) 57
docetaxel (57) 57
drugs (57) 57
chemistry, pharmaceutical (56) 56
rats, sprague-dawley (54) 54
liposomes (51) 51
pharmacology/toxicology (51) 51
pharmacy (51) 51
analysis (50) 50
bioavailability (50) 50
cell survival - drug effects (49) 49
drug-delivery (49) 49
glycerol - pharmacology (49) 49
phase-i (49) 49
polyethylene glycols - chemistry (47) 47
drug carriers - chemistry (45) 45
doxorubicin (44) 44
antineoplastic agents, phytogenic - chemistry (43) 43
delivery (43) 43
antineoplastic agents - pharmacokinetics (42) 42
hypersensitivity reactions (42) 42
antineoplastic agents - administration & dosage (41) 41
antineoplastic agents, phytogenic - therapeutic use (41) 41
biological availability (41) 41
chemistry, medicinal (41) 41
cyclosporine (41) 41
infusions, intravenous (41) 41
vehicles (41) 41
therapy (40) 40
time factors (40) 40
antineoplastic agents, phytogenic - adverse effects (39) 39
breast-cancer (39) 39
emulsions (39) 39
toxicity (39) 39
drug stability (37) 37
glycerol - chemistry (37) 37
ovarian-cancer (37) 37
absorption (36) 36
antineoplastic agents, phytogenic - pharmacology (36) 36
biochemistry & molecular biology (36) 36
drug delivery (36) 36
surface active agents (36) 36
surface-active agents - chemistry (36) 36
vehicle (36) 36
nanoscience & nanotechnology (35) 35
surfactants (35) 35
cyclosporine-a (34) 34
nanoparticles - chemistry (34) 34
biomedicine (33) 33
metastatic breast-cancer (33) 33
antitumor-activity (32) 32
breast neoplasms - drug therapy (32) 32
cells (32) 32
cytotoxicity (32) 32
permeability (32) 32
plasma (32) 32
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (723) 723
French (5) 5
Korean (4) 4
Chinese (2) 2
German (2) 2
Portuguese (2) 2
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Drug Delivery, ISSN 1071-7544, 01/2019, Volume 26, Issue 1, pp. 354 - 362
The lipophilic prodrug of hydrophobic drugs with well-designed molecular structures can form stable pure prodrug nanoparticles (NPs), but rapid NPs aggregation... 
nanomedicine | Cremophor EL | PEGylation | SN38 | lipophilic prodrug
Journal Article
Drug Delivery, ISSN 1071-7544, 01/2019, Volume 26, Issue 1, pp. 354 - 362
The lipophilic prodrug of hydrophobic drugs with well-designed molecular structures can form stable pure prodrug nanoparticles (NPs), but rapid NPs aggregation... 
nanomedicine | Cremophor EL | PEGylation | SN38 | lipophilic prodrug | Index Medicus
Journal Article
by Kang H and Cha KH and Cho W and Park J and Park HJ and Sun BK and Hyun SM and Hwang SJ
International Journal of Nanomedicine, ISSN 1178-2013, 06/2016, Volume 2016, Issue default, pp. 2921 - 2933
Han Kang,1,2 Kwang-Ho Cha,1 Wonkyung Cho,1 Junsung Park,1 Hee Jun Park,1 Bo Kyung Sun,1,2 Sang-Min Hyun,1,2 Sung-Joo Hwang1,2 1Yonsei Institute of... 
micelle solution | Cremophor EL | Restasis | cyclosporin A | dry eyes
Journal Article
Polymer Chemistry, ISSN 1759-9954, 09/2017, Volume 8, Issue 34, pp. 5033 - 5038
Physical encapsulation of hydrophobic compounds into nanocarriers that are stable in aqueous medium is of high interest as it can increase solubilization of... 
ELASTOMER | ACTIVATION | POLYMER SCIENCE | POLYMER | CREMOPHOR-EL | MICELLES | FORMULATION | SELECTION | NANOGELS | DELIVERY
Journal Article
ACS Macro Letters, ISSN 2161-1653, 2017, Volume 6, Issue 3, pp. 272 - 276
Acid-sensitive paclitaxel (PTX) polymer conjugates were designed by applying a grafting-from-drug RAFT approach. PTX was linked through either a cyclic or a... 
ACTIVATION | POLYMER SCIENCE | VEHICLES | EFFICACY | DRUG-DELIVERY | PRODRUGS | CREMOPHOR-EL | ACETALS | FORMULATION
Journal Article
ANNALS OF ONCOLOGY, ISSN 0923-7534, 02/2010, Volume 21, Issue 2, pp. 382 - 388
Background: The aim of this study was to determine the maximum tolerated dose (MTD) and the pharmacokinetic profile of Genexol-PM in Asian cancer patients.... 
POLYMERIC MICELLE FORMULATION | Genexol-PM | VEHICLE | PHENOTYPE | weekly regime | Asian | CANCER | phase 1 | ONCOLOGY | TAXOL | pharmacokinetics | INFUSIONS | HYPERSENSITIVITY REACTIONS | ABSORPTION | CREMOPHOR EL
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 01/2018, Volume 536, Issue 1, pp. 95 - 107
Combination strategy involving cyclodextrin (CD) complexation and liposomal system was investigated for Paclitaxel (PTX) to improve loading. Complexation was... 
Complexation | Cyclodextrin | Double loading | Paclitaxel | Cytotoxicity | Liposomes | Pharmacokinetic | SYSTEM | DRUG-DELIVERY | STABILITY | COMPLEXES | FORMULATION | ANTITUMOR | SOLUBILITY | NANOPARTICLES | PHARMACOLOGY & PHARMACY | IN-VIVO EVALUATION | CREMOPHOR EL | Thin films | Analysis | Pharmacy | Drugstores | Cyclodextrins | Dielectric films | Index Medicus
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 08/2019, Volume 136, pp. 104968 - 104968
The pulmonary route is a non-invasive administration route that receives growing attention. The challenge for formulation development of orally inhaled... 
Respiratory toxicity | Cytotoxicity | Inhalation therapy | Emulsifier | Macrophages | Lipid nanoparticles | CELLS | FORMULATION | CARRIERS | DELIVERY | EXCIPIENTS CREMOPHOR EL | IN-VITRO | PHARMACOLOGY & PHARMACY
Journal Article
Drug Delivery, ISSN 1071-7544, 01/2019, Volume 26, Issue 1, pp. 281 - 289
The existing of avidity cancer stem cells (CSCs) made it an optical strategy to kill cancer cells and CSCs at the same time. Here, we constructed a CSCs... 
Nanostructured lipid carriers | combined therapy | paclitaxel | salinomycin | active targeting | NANOPARTICLES | SMALL PEPTIDE | PHARMACOLOGY & PHARMACY | FORMULATION | CREMOPHOR EL
Journal Article
Molecules, ISSN 1420-3049, 02/2019, Volume 24, Issue 4, p. 728
Dantrolene sodium (DS) is the only drug specifically used for the treatment of malignant hyperthermia. Nevertheless, its clinical application is significantly... 
Mixed micelle | Cremophor EL | Pharmacokinetics | Drug safety | Dantrolene sodium | dantrolene sodium | DRUG | MALIGNANT HYPERTHERMIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | drug safety | pharmacokinetics | mixed micelle | CHEMISTRY, MULTIDISCIPLINARY | BIOAVAILABILITY | PACLITAXEL
Journal Article
Journal of Pharmacy and Pharmaceutical Sciences, ISSN 1482-1826, 2018, Volume 21, Issue 1S, pp. 177s - 191s
PURPOSE: The aim of this study was to assess the pharmacokinetics of methoxy poly(ethylene oxide)-block-poly(epsilon-caprolactone) (PEO-b-PCL) micellar... 
SOLUBILIZATION | IN-VIVO | DRUGS | PHARMACOLOGY & PHARMACY | BIODISTRIBUTION | INTESTINAL BARRIER | POLYMERIC MICELLES | FORMULATION | BIOAVAILABILITY | CREMOPHOR EL | DELIVERY
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2009, Volume 133, Issue 1, pp. 11 - 17
Journal Article
Clinical Biochemistry, ISSN 0009-9120, 04/2018, Volume 54, pp. 123 - 130
Paclitaxel (PCT) is a chemotherapeutic drug widely used for the treatment of several types of tumors, and its use is associated with severe adverse events,... 
Therapeutic drug monitoring | Liquid chromatography | Dried blood spots | Mass spectrometry | Paclitaxel | PHARMACOKINETICS | PHARMACOLOGY | MEDICAL LABORATORY TECHNOLOGY | CANCER | CREMOPHOR EL | Index Medicus
Journal Article
Analyst, ISSN 0003-2654, 08/2018, Volume 143, Issue 16, pp. 3808 - 3813
Journal Article