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Behavioural Brain Research, ISSN 0166-4328, 11/2019, Volume 373, p. 112086
Previous studies have highlighted interactions between serotonergic systems and adverse early life experience as important gene x environment determinants of... 
Htr1a | Maternal separation | Crhr2 | Gene expression | Slc6a4 | Slc22a3
Journal Article
Hypertension (Dallas, Tex. : 1979), ISSN 0194-911X, 10/2018, Volume 72, Issue 4, pp. 994 - 1001
This study tested the hypothesis that corticotropin-releasing hormone (CRH) receptors in the nucleus of the solitary tract (NTS) contribute to the hypertension... 
CRFR2 | CRF | CRH | NTS | intermittent hypoxia | hypertension | CRHR2
Journal Article
Cellular Signalling, ISSN 0898-6568, 06/2019, Volume 58, pp. 119 - 130
Clinical studies have elucidated the negative correlation between microtubules-associated protein 1 light chain 3-B (LC3B) protein expression and overall... 
CRHR1&CRHR2 | Corticortropin-releasing hormone family | LC3B | Autophagy | Migration | Research | Hormones | G proteins | Oncology, Experimental | Cancer | Membrane proteins
Journal Article
Molecular Metabolism, ISSN 2212-8778, 2016, Volume 5, Issue 7, pp. 449 - 458
Abstract Objective Complex local crosstalk amongst endocrine cells within the islet ensures tight coordination of their endocrine output. This is illustrated... 
Endocrinology & Metabolism | Delta cell | Alpha cell | Ghrelin | Somatostatin release | Transcriptome | Beta cell | RNA | INSULIN-SECRETION | MOUSE | RECEPTOR | PROLIFERATION | ENDOCRINE PANCREAS | GROWTH-HORMONE | GLUCOSE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | GLUCAGON
Journal Article
by Jin, L and Li, CH and Li, R and Sun, ZX and Fang, XJ and Li, SN
JOURNAL OF MOLECULAR ENDOCRINOLOGY, ISSN 0952-5041, 06/2014, Volume 52, Issue 3, pp. 255 - 267
Peripheral corticotropin-releasing hormone receptors (CRHRs) are G protein-coupled receptors that play different roles depending on tissue types. Previously,... 
ARACHIDONIC-ACID RELEASE | ACTIVATION | ADENOCARCINOMA | apoptosis | cPLA | CRHR1 | FIBROBLASTS | CRHR2 | CUSHINGS-SYNDROME | IN-VITRO | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | migration | TUMOR-GROWTH | EXPRESSION | UROCORTIN
Journal Article
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, ISSN 1552-4841, 01/2013, Volume 162, Issue 1, pp. 78 - 85
Major depressive disorder (MDD) and panic disorder (PD) are common and disabling medical disorders with stress and genetic components. Dysregulation of the... 
major depressive disorder | SNP | panic disorder | CRHR1 | CRHR2 | Major depressive disorder | Panic disorder | Panic attacks | Panic disorders | Genes
Journal Article
International Journal of Cancer, ISSN 0020-7136, 01/2018, Volume 142, Issue 2, pp. 334 - 346
Journal Article
Journal of Affective Disorders, ISSN 0165-0327, 2007, Volume 104, Issue 1, pp. 83 - 90
Abstract Background Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been observed in major depression. Normalization of HPA axis has been... 
Psychiatry | Follow-up study | SSRIs | Major depression | HPA axis | CRH-BP | Clinical response | CRHR1 | CRHR2 | FKBP5 | HORMONE-BINDING PROTEIN | ANXIETY | PSYCHIATRY | AFFECTIVE-DISORDERS | GLUCOCORTICOID-RECEPTOR GENE | HIGH FAMILIAL RISK | POLYMORPHISM | follow-up study | CRH TEST | CLINICAL NEUROLOGY | clinical response | CORTICOTROPIN-RELEASING-FACTOR | RECURRENT | PITUITARY-ADRENOCORTICAL REGULATION | major depression | Citalopram - pharmacology | Humans | Suicide, Attempted - statistics & numerical data | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Antidepressive Agents, Second-Generation - therapeutic use | Case-Control Studies | Adult | Female | Surveys and Questionnaires | Seasons | Hypothalamo-Hypophyseal System - physiopathology | Depressive Disorder, Major - drug therapy | Depressive Disorder, Major - physiopathology | Hypothalamo-Hypophyseal System - drug effects | Pituitary-Adrenal System - physiopathology | Pituitary-Adrenal System - drug effects | Risk Factors | Antidepressive Agents, Second-Generation - pharmacology | Tacrolimus Binding Proteins - genetics | Carrier Proteins - genetics | Depressive Disorder, Major - genetics | Alleles | Citalopram - therapeutic use | Polymorphism, Genetic - genetics | Genetic Variation - genetics | Genome, Human | Genetic research | Serotonin uptake inhibitors | Major depressive disorder
Journal Article
Journal of Cancer, ISSN 1837-9664, 2014, Volume 5, Issue 6, pp. 465 - 471
Background: Lung cancer still remains the leading cause of cancer for men after prostate cancer and breast cancer for women. Angiogenesis is considered a major... 
FIGF | FLT4 | Lung cancer | KDR | Carcinoid | HIF1A | CRHR2 | SURVIVAL | PLACEBO | METASTASIS | TUMOR ANGIOGENESIS | carcinoid | CHEMOTHERAPY | lung cancer | CELL LUNG-CANCER | TRIAL | ONCOLOGY | DOUBLE-BLIND | OBSERVER VARIATION | PLUS ERLOTINIB
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2000, Volume 24, Issue 4, pp. 403 - 409
The actions of corticotropin-releasing hormone (Crh), a mediator of endocrine and behavioural responses to stress, and the related hormone urocortin (Ucn) are... 
HEART | CELLS | ANXIETY | FOOD-INTAKE | CARDIAC MYOCYTES | GENETICS & HEREDITY | RATS | NEUROPEPTIDE | EXPRESSION | PEPTIDE | UROCORTIN | Adaptation, Psychological - physiology | Urocortins | Receptors, Corticotropin-Releasing Hormone - metabolism | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Anorexia - genetics | Receptors, Corticotropin-Releasing Hormone - deficiency | Hypertension - blood | Heart Rate - drug effects | Cardiovascular System - physiopathology | Adaptation, Physiological - genetics | Female | Corticosterone - blood | Hypertension - genetics | Hypothalamo-Hypophyseal System - physiopathology | Adrenocorticotropic Hormone - blood | Exploratory Behavior | Gene Targeting | Pituitary-Adrenal System - physiopathology | Echocardiography | Pituitary-Adrenal System - metabolism | Stress, Physiological - genetics | Ventricular Function, Left - drug effects | Corticotropin-Releasing Hormone - metabolism | Hypothalamo-Hypophyseal System - metabolism | Corticotropin-Releasing Hormone - pharmacology | Mice, Knockout | Eating - drug effects | Animals | Grooming | Cardiovascular System - metabolism | Anorexia - chemically induced | Mice | Corticotropin releasing hormone | Hormone receptors | Physiological aspects | Genetic aspects | Diagnosis | Research | Cardiovascular diseases | Risk factors | urocortin | Crhr2 gene | corticosterone | hypophagia | Crhr gene
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2000, Volume 24, Issue 4, pp. 415 - 419
Corticotropin-releasing hormone (Crh), a 41-residue polypeptide, activates two G-protein-coupled receptors, Crhr1 (refs 3-5) and Crhr2 (refs 6-9), causing... 
HEART | ANXIETY | IMPAIRED STRESS-RESPONSE | MOUSE | NEUROENDOCRINE | GENETICS & HEREDITY | MICE | RAT-BRAIN | IDENTIFICATION | EXPRESSION | SAUVAGINE | Phosphorylation | Receptors, Corticotropin-Releasing Hormone - metabolism | Edema - genetics | Injections, Intraventricular | Motor Activity - drug effects | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Brain - metabolism | Gene Deletion | Stress, Physiological - metabolism | Female | Restraint, Physical | Corticotropin-Releasing Hormone - administration & dosage | Corticosterone - blood | Hypothalamo-Hypophyseal System - physiology | Weight Gain | Adrenocorticotropic Hormone - blood | Pituitary-Adrenal System - physiology | Hot Temperature - adverse effects | Maze Learning - physiology | Mice, Inbred C57BL | Proto-Oncogene Proteins c-fos - metabolism | Stress, Physiological - physiopathology | Corticotropin-Releasing Hormone - metabolism | Feeding Behavior - physiology | Mice, Knockout | Anxiety - genetics | Animals | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Stress, Physiological - blood | Cyclic AMP Response Element-Binding Protein - metabolism | Sex Factors | Anxiety Disorders - genetics | Mice | Corticotropin releasing hormone | Hormone receptors | Gene mutations | Physiological aspects | Genetic aspects | Research | Health aspects | Crhr2 gene | Crhr1 gene
Journal Article