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science & technology (1106) 1106
life sciences & biomedicine (871) 871
crispr (536) 536
humans (527) 527
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biochemistry & molecular biology (421) 421
animals (407) 407
crispr-associated proteins - genetics (393) 393
crispr-associated proteins - metabolism (379) 379
clustered regularly interspaced short palindromic repeats (332) 332
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crispr-associated protein 9 - metabolism (294) 294
gene editing - methods (294) 294
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rna, guide - genetics (278) 278
crispr-associated protein 9 - genetics (258) 258
deoxyribonucleic acid--dna (237) 237
mutation (231) 231
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science & technology - other topics (225) 225
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base sequence (216) 216
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clustered regularly interspaced short palindromic repeats - genetics (189) 189
rna, guide - metabolism (175) 175
genetic engineering (165) 165
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cas9 (158) 158
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research (141) 141
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genetic aspects (133) 133
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hek293 cells (128) 128
bacterial proteins - metabolism (127) 127
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genome (121) 121
analysis (112) 112
endonucleases - metabolism (112) 112
genome editing (109) 109
endonucleases - genetics (105) 105
microbiology (104) 104
dna - genetics (100) 100
dna - metabolism (95) 95
genetics (94) 94
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biology (92) 92
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genetic research (83) 83
molecular sequence data (83) 83
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protein binding (77) 77
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nuclease (76) 76
science (74) 74
gene targeting (73) 73
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crispr-associated proteins (72) 72
mutagenesis (70) 70
plasmids (70) 70
nucleases (68) 68
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plasmids - genetics (63) 63
dna cleavage (61) 61
bacterial proteins - chemistry (59) 59
cell line, tumor (58) 58
dna - chemistry (57) 57
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nucleic acid conformation (56) 56
biochemical research methods (55) 55
dna sequencing (53) 53
gene targeting - methods (52) 52
nucleotide sequence (52) 52
stem cells (52) 52
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gene deletion (50) 50
gene knockout techniques (50) 50
mice, inbred c57bl (50) 50
nucleotide sequencing (50) 50
substrate specificity (50) 50
rna, bacterial - metabolism (49) 49
dna repair (48) 48
life sciences (48) 48
bacteria - genetics (47) 47
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Nature (London), ISSN 1476-4687, 12/2014, Volume 517, Issue 7536, pp. 583 - 588
Journal Article
Nature (London), ISSN 0028-0836, 06/2019, Volume 571, Issue 7764, pp. 219 - 225
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 04/2014, Volume 111, Issue 18, pp. 6618 - 6623
Journal Article
Molecular cell, ISSN 1097-2765, 04/2017, Volume 66, Issue 2, pp. 221 - 233.e4
Journal Article
Annual review of genetics, ISSN 0066-4197, 12/2011, Volume 45, Issue 1, pp. 273 - 297
Journal Article