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Seminars in cell & developmental biology, ISSN 1084-9521, 05/2019
CRISPR-Cas9 is an RNA guided endonuclease that has revolutionized the ability to edit genome and introduce desired manipulations in the target genomic... 
Journal Article
NATURE BIOTECHNOLOGY, ISSN 1087-0156, 08/2018, Volume 36, Issue 8, pp. 765 - 765
CRISPR-Cas9 is poised to become the gene editing tool of choice in clinical contexts. Thus far, exploration of Cas9-induced genetic alterations has been... 
CRISPR/CAS9 | SPECIFICITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DNA | EMBRYONIC STEM-CELLS | RNAS | CAS9 | MUTATIONS | NUCLEASES
Journal Article
Development Genes and Evolution, ISSN 0949-944X, 12/2014, Volume 225, Issue 1, pp. 55 - 62
Journal Article
Nature Communications, ISSN 2041-1723, 02/2017, Volume 8, Issue 1, p. 14454
Gene replacement therapies utilizing adeno-associated viral (AAV) vectors hold great promise for treating Duchenne muscular dystrophy (DMD). A related approach... 
CRISPR-CAS9 | SKELETAL | EXPRESSION | VECTORS | MULTIDISCIPLINARY SCIENCES | MDX MICE
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 03/2019, Volume 18, Issue 3, pp. 1054 - 1063
The CRISPR-Cas9 system is a genomic editing tool widely used in basic research and under investigation for potential applications in gene therapies for human... 
Proteome | Phosphoproteome | AP-MS | CRISPR-Cas9 | Transcriptome
Journal Article
BioTechniques, ISSN 0736-6205, 04/2019, Volume 66, Issue 4, pp. 198 - 201
The CRISPR/Cas9 system has recently emerged as a powerful tool for functional genomic studies and has been adopted for many organisms, including . Previously,... 
genome editing | CRISPR/Cas9 | homologous recombination
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2018, Volume 500, Issue 2, pp. 177 - 183
Nuclear receptor coactivator 5 (NCOA5) plays important roles in the development of a variety of malignancies. However, the underlying mechanisms remain... 
HCC | CRISPR/cas9 | NCOA5 | EMT
Journal Article
Insect Biochemistry and Molecular Biology, ISSN 0965-1748, 06/2019, Volume 109, pp. 43 - 51
The spermatogenesis of animal is essential for the reproduction and a very large number of genes participate in this procession. The ( ) is identified... 
Bombyx mori | CRISPR/Cas9 | Spermatogenesis | Maelstrom
Journal Article
Trends in Cardiovascular Medicine, ISSN 1050-1738, 2019
The CRISPR/Cas9 system is a precisely targeted bacterial defense system, used to control invading viruses. This technology has many potential applications... 
CRISPR/Cas9 | Cardiovascular disease | Genome editing
Journal Article
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 05/2017, Volume 376, Issue 21, pp. 2094 - 2094
Journal Article
Frontiers in genetics, ISSN 1664-8021, 2018, Volume 9, p. 233
Tylosis with esophageal cancer syndrome (TOC) is a rare autosomal dominant proliferative skin disease caused by missense mutations in the rhomboid 5 homolog 2... 
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2019, Volume 520, Issue 1, pp. 60 - 66
Journal Article
Nature communications, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2019 - 1
The original version of this Article contained an error in Figure 5. In the panel c, the right bar chart was inadvertently replaced with a duplicate of the... 
Journal Article
Small, ISSN 1613-6810, 09/2019, Volume 15, Issue 38, pp. 1970205 - n/a
In article number 1902686, Jie Wang, Fengmin Lu, and co‐workers indicate the potential of exosomes as a safe and effective delivery vehicle of functional gRNA... 
CRISPR/Cas9 | exosomes | delivery systems | Proteins | Genetic modification
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 12/2019, Volume 306, pp. 62 - 70
The CRISPR-Cas9 system is a new tool that has been extensively used for genome editing. The system is composed of a Cas9 endonuclease, which has the function... 
Batch cultivation | CRISPR-Cas9 | Defined medium | Cas9 endonuclease
Journal Article
Trends in molecular medicine, ISSN 1471-4914, 08/2019
Since its emergence, the application of CRISPR-associated nuclease 9 (Cas9) technology in cancer research has accelerated studies to investigate many aspects... 
Journal Article
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