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Seminars in cell & developmental biology, ISSN 1084-9521, 05/2019
CRISPR-Cas9 is an RNA guided endonuclease that has revolutionized the ability to edit genome and introduce desired manipulations in the target genomic... 
Journal Article
NATURE BIOTECHNOLOGY, ISSN 1087-0156, 08/2018, Volume 36, Issue 8, pp. 765 - 765
CRISPR-Cas9 is poised to become the gene editing tool of choice in clinical contexts. Thus far, exploration of Cas9-induced genetic alterations has been... 
CRISPR/CAS9 | SPECIFICITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DNA | EMBRYONIC STEM-CELLS | RNAS | CAS9 | MUTATIONS | NUCLEASES
Journal Article
Development Genes and Evolution, ISSN 0949-944X, 12/2014, Volume 225, Issue 1, pp. 55 - 62
Journal Article
Nature Communications, ISSN 2041-1723, 02/2017, Volume 8, Issue 1, p. 14454
Gene replacement therapies utilizing adeno-associated viral (AAV) vectors hold great promise for treating Duchenne muscular dystrophy (DMD). A related approach... 
CRISPR-CAS9 | SKELETAL | EXPRESSION | VECTORS | MULTIDISCIPLINARY SCIENCES | MDX MICE
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 03/2019, Volume 18, Issue 3, pp. 1054 - 1063
The CRISPR-Cas9 system is a genomic editing tool widely used in basic research and under investigation for potential applications in gene therapies for human... 
Proteome | Phosphoproteome | AP-MS | CRISPR-Cas9 | Transcriptome
Journal Article
BioTechniques, ISSN 0736-6205, 04/2019, Volume 66, Issue 4, pp. 198 - 201
The CRISPR/Cas9 system has recently emerged as a powerful tool for functional genomic studies and has been adopted for many organisms, including . Previously,... 
genome editing | CRISPR/Cas9 | homologous recombination
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2018, Volume 500, Issue 2, pp. 177 - 183
Nuclear receptor coactivator 5 (NCOA5) plays important roles in the development of a variety of malignancies. However, the underlying mechanisms remain... 
HCC | CRISPR/cas9 | NCOA5 | EMT
Journal Article
Insect Biochemistry and Molecular Biology, ISSN 0965-1748, 06/2019, Volume 109, pp. 43 - 51
The spermatogenesis of animal is essential for the reproduction and a very large number of genes participate in this procession. The ( ) is identified... 
Bombyx mori | CRISPR/Cas9 | Spermatogenesis | Maelstrom
Journal Article
Trends in Cardiovascular Medicine, ISSN 1050-1738, 2019
The CRISPR/Cas9 system is a precisely targeted bacterial defense system, used to control invading viruses. This technology has many potential applications... 
CRISPR/Cas9 | Cardiovascular disease | Genome editing
Journal Article
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 05/2017, Volume 376, Issue 21, pp. 2094 - 2094
Journal Article
Frontiers in genetics, ISSN 1664-8021, 2018, Volume 9, p. 233
Tylosis with esophageal cancer syndrome (TOC) is a rare autosomal dominant proliferative skin disease caused by missense mutations in the rhomboid 5 homolog 2... 
Journal Article
Nature communications, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2019 - 1
The original version of this Article contained an error in Figure 5. In the panel c, the right bar chart was inadvertently replaced with a duplicate of the... 
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2019
Journal Article
Small, ISSN 1613-6810, 09/2019, Volume 15, Issue 38, pp. 1970205 - n/a
In article number 1902686 , Jie Wang, Fengmin Lu, and co‐workers indicate the potential of exosomes as a safe and effective delivery vehicle of functional gRNA... 
CRISPR/Cas9 | exosomes | delivery systems | Proteins | Genetic modification
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 12/2019, Volume 306, pp. 62 - 70
The CRISPR-Cas9 system is a new tool that has been extensively used for genome editing. The system is composed of a Cas9 endonuclease, which has the function... 
Batch cultivation | CRISPR-Cas9 | Defined medium | Cas9 endonuclease
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 01/2020, Volume 499, p. 110593
In the present study, Amh was found to be abundantly expressed in the granulosa cells of the primary growth follicles, and Amhr2 in the granulosa cells,... 
Folliculogenesis arrest | Anti-Müllerian hormone | CRISPR/Cas9 | Fertility | Ovary hypertrophy
Journal Article
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